| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capivasertib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capivasertib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SDK1 | sidekick cell adhesion molecule 1 | 0.217445 |
| NAV2 | neuron navigator 2 | 0.121366 |
| CDH13 | cadherin 13 | 0.11055 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0985498 |
| FAM20C | family with sequence similarity 20, member C | 0.094493 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0931738 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0904643 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0887631 |
| MTSS1 | metastasis suppressor 1 | 0.0788251 |
| HMGA2 | high mobility group AT-hook 2 | 0.0748472 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0743777 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0741329 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0733868 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0724368 |
| GLCCI1 | glucocorticoid induced 1 | 0.0708696 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0686617 |
| IFI44L | interferon-induced protein 44-like | 0.0648889 |
| ANGPTL4 | angiopoietin-like 4 | 0.0647658 |
| EFNA5 | ephrin-A5 | 0.0600759 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0584081 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0569795 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.055013 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0542932 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0527534 |
| SEPTIN9 | septin 9 | 0.0521664 |
| PRELID2 | PRELI domain containing 2 | 0.0521267 |
| DTNA | dystrobrevin, alpha | 0.0512693 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0501388 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0482096 |
| INTS6 | integrator complex subunit 6 | 0.0440743 |
| RPL37A | ribosomal protein L37a | 0.0437629 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0437116 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0435701 |
| ZNF638 | zinc finger protein 638 | 0.043442 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0426372 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0418971 |
| PYGL | phosphorylase, glycogen, liver | 0.0416631 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0409285 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0399669 |
| NHSL1 | NHS-like 1 | 0.0387371 |
| RPS12 | ribosomal protein S12 | 0.0380773 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0374653 |
| FAM219A | family with sequence similarity 219, member A | 0.0372008 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0369249 |
| ATXN1 | ataxin 1 | 0.0366712 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0362497 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0355558 |
| SMAD3 | SMAD family member 3 | 0.0354194 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0348079 |
| EGFR | epidermal growth factor receptor | 0.0343607 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0343276 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0337092 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0336987 |
| SIK3 | SIK family kinase 3 | 0.03356 |
| ANXA10 | annexin A10 | 0.0332403 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0327772 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.0326376 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0325612 |
| PTK2 | protein tyrosine kinase 2 | 0.0322109 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0317895 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0315507 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.031531 |
| RPL37 | ribosomal protein L37 | 0.0305385 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0301861 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0301127 |
| TGM2 | transglutaminase 2 | 0.0300073 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0298569 |
| NAV1 | neuron navigator 1 | 0.0292331 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0289957 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.028747 |
| CDK14 | cyclin-dependent kinase 14 | 0.0283424 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0281653 |
| GRB10 | growth factor receptor-bound protein 10 | 0.028076 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0277966 |
| RCOR1 | REST corepressor 1 | 0.0270205 |
| VEGFC | vascular endothelial growth factor C | 0.0270064 |
| SLC44A5 | solute carrier family 44, member 5 | 0.0269953 |
| NLK | nemo-like kinase | 0.0269691 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.02696 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.026868 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0267876 |
| NRG1 | neuregulin 1 | 0.0267721 |
| AUTS2 | autism susceptibility candidate 2 | 0.0264968 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.026483 |
| PRKCA | protein kinase C, alpha | 0.0259965 |
| CMIP | c-Maf inducing protein | 0.025962 |
| STK38L | serine/threonine kinase 38 like | 0.0258386 |
| CTBP2 | C-terminal binding protein 2 | 0.0255132 |
| NOTCH2 | notch 2 | 0.0254648 |
| LOXL2 | lysyl oxidase-like 2 | 0.0253402 |
| NUMB | numb homolog (Drosophila) | 0.0252678 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0249966 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0242723 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0242151 |
| AVIL | advillin | 0.0239829 |
| ATF7 | activating transcription factor 7 | 0.0239249 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0238937 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0238795 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0236992 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0236464 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.223161 |
| CD44 | CD44 molecule (Indian blood group) | -0.141172 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.121286 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.091887 |
| RBM39 | RNA binding motif protein 39 | -0.083782 |
| TMSB10 | thymosin beta 10 | -0.0782808 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0701843 |
| VIM | vimentin | -0.0689619 |
| LOX | lysyl oxidase | -0.0673124 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0638022 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0611186 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.06078 |
| IER3 | immediate early response 3 | -0.0605553 |
| OSMR | oncostatin M receptor | -0.0583052 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0569657 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0549583 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0541826 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0523691 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0514772 |
| EGR1 | early growth response 1 | -0.0511124 |
| GOLGA4 | golgin A4 | -0.0507677 |
| PTMA | prothymosin, alpha | -0.0488476 |
| FN1 | fibronectin 1 | -0.0487006 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0462272 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0447924 |
| FTL | ferritin, light polypeptide | -0.044741 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0412397 |
| TNNC1 | troponin C type 1 (slow) | -0.0412035 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0402554 |
| SYAP1 | synapse associated protein 1 | -0.0379742 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0376936 |
| SBF2 | SET binding factor 2 | -0.0365315 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0357867 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0351068 |
| RPLP1 | ribosomal protein, large, P1 | -0.0348092 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0344826 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0342606 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0341475 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0338718 |
| YME1L1 | YME1-like 1 ATPase | -0.0323249 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0316359 |
| MORF4L2 | mortality factor 4 like 2 | -0.0310957 |
| SPAG9 | sperm associated antigen 9 | -0.0310253 |
| YBX3 | Y box binding protein 3 | -0.0305917 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0304502 |
| DST | dystonin | -0.0301372 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0300074 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0299176 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0295035 |
| MAP1B | microtubule-associated protein 1B | -0.0291176 |
| CANX | calnexin | -0.029008 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0287004 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0285685 |
| NTN4 | netrin 4 | -0.0282052 |
| TXNRD1 | thioredoxin reductase 1 | -0.027833 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0274894 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0272742 |
| TBC1D15 | TBC1 domain family, member 15 | -0.0272388 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0270976 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.027028 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0267924 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0267276 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0266981 |
| OGA | O-GlcNAcase | -0.0266308 |
| TMSB4X | thymosin beta 4, X-linked | -0.0266184 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0266151 |
| RIOK3 | RIO kinase 3 | -0.0263179 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0262054 |
| WDR45B | WD repeat domain 45B | -0.0259842 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0255932 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0253665 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0250933 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0246089 |
| KIF5B | kinesin family member 5B | -0.0244541 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0243119 |
| TMEM123 | transmembrane protein 123 | -0.0241035 |
| KYNU | kynureninase | -0.0240426 |
| ZFP91 | ZFP91 zinc finger protein | -0.0239406 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0233466 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0232645 |
| NF1 | neurofibromin 1 | -0.0230819 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0229214 |
| CDK17 | cyclin-dependent kinase 17 | -0.0227551 |
| CALR | calreticulin | -0.0225326 |
| OXSR1 | oxidative stress responsive 1 | -0.022113 |
| FOXP1 | forkhead box P1 | -0.0220262 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0219943 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0219147 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0218478 |
| AOPEP | aminopeptidase O (putative) | -0.0217586 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0216329 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0216242 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0214849 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0214242 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0213654 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0212425 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0212197 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0211502 |
| TPR | translocated promoter region, nuclear basket protein | -0.0210899 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0209182 |
