| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capivasertib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capivasertib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDGFC | platelet derived growth factor C | 0.0862199 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0710847 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0613051 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0599724 |
| ZNF292 | zinc finger protein 292 | 0.0591093 |
| QKI | QKI, KH domain containing, RNA binding | 0.0578565 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0514185 |
| JMJD1C | jumonji domain containing 1C | 0.0506808 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.050231 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0493951 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0452415 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0418572 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0415272 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0403468 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0386952 |
| SETD5 | SET domain containing 5 | 0.0379486 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0370243 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0366933 |
| CDC73 | cell division cycle 73 | 0.0354199 |
| RPS2 | ribosomal protein S2 | 0.034506 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0343784 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.034364 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0334746 |
| TFG | TRK-fused gene | 0.0317753 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.031682 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0316513 |
| ANKRD17 | ankyrin repeat domain 17 | 0.030905 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0308806 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0302851 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0301671 |
| DENND4A | DENN/MADD domain containing 4A | 0.0287311 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0280943 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0280686 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0280144 |
| ATOSA | atos homolog A | 0.0274943 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0272331 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0268485 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0267169 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0266217 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0261075 |
| CYTH3 | cytohesin 3 | 0.0253371 |
| CRY1 | cryptochrome circadian clock 1 | 0.0252753 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0248294 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0246837 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0242362 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0239357 |
| RPL27 | ribosomal protein L27 | 0.0239226 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0238919 |
| MRTFA | myocardin related transcription factor A | 0.0232216 |
| FAM168A | family with sequence similarity 168, member A | 0.0230704 |
| NUP58 | nucleoporin 58 | 0.0230307 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.022936 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0229212 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0226671 |
| RPL28 | ribosomal protein L28 | 0.0226221 |
| ECT2 | epithelial cell transforming 2 | 0.0224295 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0220773 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0215908 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0215451 |
| USP24 | ubiquitin specific peptidase 24 | 0.0215215 |
| RBM39 | RNA binding motif protein 39 | 0.0213878 |
| RTN4 | reticulon 4 | 0.0213604 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0213468 |
| HELZ | helicase with zinc finger | 0.0212682 |
| HDAC9 | histone deacetylase 9 | 0.0211498 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0210145 |
| SESN2 | sestrin 2 | 0.020974 |
| CTBP2 | C-terminal binding protein 2 | 0.0209086 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.020893 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0204146 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0204065 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0203883 |
| SPPL3 | signal peptide peptidase like 3 | 0.0203229 |
| CCNL1 | cyclin L1 | 0.020081 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0196799 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0196413 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0196078 |
| USP15 | ubiquitin specific peptidase 15 | 0.0195194 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0195159 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0195002 |
| ATP9B | ATPase, class II, type 9B | 0.0194582 |
| TRAF3 | TNF receptor-associated factor 3 | 0.0194378 |
| MEF2A | myocyte enhancer factor 2A | 0.0190651 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | 0.0188339 |
| MTMR3 | myotubularin related protein 3 | 0.0186773 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0185958 |
| SLTM | SAFB-like, transcription modulator | 0.0185484 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0184846 |
| CUL3 | cullin 3 | 0.01846 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0183937 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0183691 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0183669 |
| CCNY | cyclin Y | 0.0182827 |
| NCKAP1 | NCK-associated protein 1 | 0.0181924 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0181239 |
| COG6 | component of oligomeric golgi complex 6 | 0.0180666 |
| RPS25 | ribosomal protein S25 | 0.0180374 |
| COG5 | component of oligomeric golgi complex 5 | 0.0180346 |
| OLA1 | Obg-like ATPase 1 | 0.0179627 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0179142 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.389755 |
| AHNAK | AHNAK nucleoprotein | -0.130028 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.126894 |
| BMP10 | bone morphogenetic protein 10 | -0.123511 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.111889 |
| TMSB4X | thymosin beta 4, X-linked | -0.104656 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0949386 |
| VCL | vinculin | -0.094562 |
| PKM | pyruvate kinase, muscle | -0.0922369 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0895935 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0886046 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0851626 |
| CCND1 | cyclin D1 | -0.080338 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0769892 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0751942 |
| FOXP1 | forkhead box P1 | -0.0715828 |
| NBEA | neurobeachin | -0.0701017 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0690655 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0633201 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0619481 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0607234 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0593742 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0563858 |
| RPLP1 | ribosomal protein, large, P1 | -0.0547074 |
| GLI3 | GLI family zinc finger 3 | -0.0539975 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0505162 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0500766 |
| TXNRD1 | thioredoxin reductase 1 | -0.0487642 |
| S100A4 | S100 calcium binding protein A4 | -0.0485622 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0481123 |
| MYO5C | myosin VC | -0.0461457 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0459819 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0456607 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.045146 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0435193 |
| S100A6 | S100 calcium binding protein A6 | -0.0433128 |
| ACTG1 | actin gamma 1 | -0.0421265 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0420719 |
| ENO1 | enolase 1, (alpha) | -0.0415055 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0404264 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.040147 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0401127 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0396704 |
| RPL4 | ribosomal protein L4 | -0.0394904 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0388356 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0386695 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0386036 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0385484 |
| ZNF438 | zinc finger protein 438 | -0.0385121 |
| CENPF | centromere protein F, 350/400kDa | -0.0384739 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0383028 |
| DUSP4 | dual specificity phosphatase 4 | -0.0381284 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.038024 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0377171 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0376959 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0373926 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0367961 |
| RPS27A | ribosomal protein S27a | -0.0365088 |
| RPL31 | ribosomal protein L31 | -0.0363215 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0361262 |
| MKI67 | marker of proliferation Ki-67 | -0.0360175 |
| RPLP0 | ribosomal protein, large, P0 | -0.0354756 |
| PYGB | phosphorylase, glycogen; brain | -0.0353068 |
| NEBL | nebulette | -0.0352408 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0350386 |
| EHBP1 | EH domain binding protein 1 | -0.0350365 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0350058 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0348456 |
| FLNB | filamin B, beta | -0.0343293 |
| EFNA5 | ephrin-A5 | -0.0341471 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0335267 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0335266 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0334387 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0333021 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0326699 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0324554 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0314637 |
| SQSTM1 | sequestosome 1 | -0.0311071 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0309629 |
| EZR | ezrin | -0.0306688 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0304458 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0303617 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0302745 |
| HMGB1 | high mobility group box 1 | -0.0298893 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0296066 |
| GSE1 | Gse1 coiled-coil protein | -0.0292807 |
| PGK1 | phosphoglycerate kinase 1 | -0.0292523 |
| RPL23 | ribosomal protein L23 | -0.0291334 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0288367 |
| NFIA | nuclear factor I/A | -0.0288073 |
| UBC | ubiquitin C | -0.0284506 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0284475 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0284282 |
| RPL34 | ribosomal protein L34 | -0.0283543 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0281644 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0280047 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0279969 |
| RPL19 | ribosomal protein L19 | -0.0276874 |
| GNAS | GNAS complex locus | -0.0274279 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0269543 |
