| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capivasertib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capivasertib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.129986 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.117044 |
| SDC4 | syndecan 4 | 0.0928001 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0915373 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0908614 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0856552 |
| CADM1 | cell adhesion molecule 1 | 0.0759169 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0752554 |
| FAM13A | family with sequence similarity 13, member A | 0.0707159 |
| FN1 | fibronectin 1 | 0.0678258 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0671839 |
| HIP1 | huntingtin interacting protein 1 | 0.0601127 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.058641 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0577006 |
| RNF145 | ring finger protein 145 | 0.0567392 |
| ZNF395 | zinc finger protein 395 | 0.0562817 |
| ATP13A3 | ATPase type 13A3 | 0.051668 |
| CD44 | CD44 molecule (Indian blood group) | 0.0501077 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0497971 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0496992 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0473351 |
| ANXA2 | annexin A2 | 0.0471814 |
| TMSB10 | thymosin beta 10 | 0.046034 |
| RTN4 | reticulon 4 | 0.0459463 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0453877 |
| ARRDC3 | arrestin domain containing 3 | 0.04437 |
| OGA | O-GlcNAcase | 0.0428971 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0428896 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0425406 |
| ECE1 | endothelin converting enzyme 1 | 0.0421224 |
| RLF | rearranged L-myc fusion | 0.0413621 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0413471 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0412329 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0399043 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0397815 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0397179 |
| NDRG1 | N-myc downstream regulated 1 | 0.039392 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.039042 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0383229 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0377953 |
| MYO9B | myosin IXB | 0.0377467 |
| DSCAM | Down syndrome cell adhesion molecule | 0.037574 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0368377 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0367579 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0366534 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0364211 |
| WASF2 | WAS protein family, member 2 | 0.0361619 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0359251 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0355792 |
| SQSTM1 | sequestosome 1 | 0.0352676 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.034625 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0344712 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0341959 |
| AHNAK | AHNAK nucleoprotein | 0.0341317 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0335047 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0330229 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0327328 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0320489 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0319013 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0317151 |
| XPO1 | exportin 1 | 0.0313873 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0312664 |
| AFF4 | AF4/FMR2 family, member 4 | 0.031246 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0304009 |
| SYNJ2 | synaptojanin 2 | 0.0303456 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0301354 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0299855 |
| RNF24 | ring finger protein 24 | 0.0298148 |
| RINT1 | RAD50 interactor 1 | 0.0297164 |
| PALLD | palladin, cytoskeletal associated protein | 0.0297143 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0295575 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0294863 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0291229 |
| HPCAL1 | hippocalcin-like 1 | 0.0290652 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0288621 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0287775 |
| MATR3 | matrin 3 | 0.0281391 |
| ACVR1 | activin A receptor, type I | 0.0279048 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0277408 |
| RBM39 | RNA binding motif protein 39 | 0.0276059 |
| RYBP | RING1 and YY1 binding protein | 0.0275862 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0275556 |
| COL1A1 | collagen, type I, alpha 1 | 0.0275264 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0273413 |
| SP100 | SP100 nuclear antigen | 0.0273344 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0271764 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0271734 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.0271733 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0271045 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0270926 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0270511 |
| SRP54 | signal recognition particle 54kDa | 0.027036 |
| CLIC4 | chloride intracellular channel 4 | 0.0270356 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0267935 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0267542 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0265367 |
| ZNF292 | zinc finger protein 292 | 0.0262279 |
| CCNI | cyclin I | 0.0262202 |
| NRXN3 | neurexin 3 | 0.0261388 |
| SEPTIN7 | septin 7 | 0.0257544 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.152449 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.140885 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0880117 |
| MT2A | metallothionein 2A | -0.0880104 |
| EGFR | epidermal growth factor receptor | -0.0763132 |
| CDH13 | cadherin 13 | -0.0762033 |
| IL6 | interleukin 6 | -0.0636591 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0612519 |
| VIM | vimentin | -0.0593756 |
| RPL37A | ribosomal protein L37a | -0.0581687 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0568947 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0543791 |
| DST | dystonin | -0.0530279 |
| RPS6 | ribosomal protein S6 | -0.0453694 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0447695 |
| TNS3 | tensin 3 | -0.0446904 |
| ACTG1 | actin gamma 1 | -0.043253 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0432283 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0426222 |
| EXOC4 | exocyst complex component 4 | -0.0421181 |
| RPS8 | ribosomal protein S8 | -0.0408068 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0403114 |
| RPS12 | ribosomal protein S12 | -0.0397701 |
| RAD51B | RAD51 paralog B | -0.0375984 |
| ASPH | aspartate beta-hydroxylase | -0.0363815 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0363078 |
| B2M | beta-2-microglobulin | -0.0362819 |
| EFNA5 | ephrin-A5 | -0.0359978 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0348265 |
| RPLP2 | ribosomal protein, large, P2 | -0.0337651 |
| SMYD3 | SET and MYND domain containing 3 | -0.0329572 |
| RORA | RAR-related orphan receptor A | -0.032749 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0322357 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0317433 |
| WWOX | WW domain containing oxidoreductase | -0.0315819 |
| RPL11 | ribosomal protein L11 | -0.0314501 |
| COL5A2 | collagen, type V, alpha 2 | -0.0314061 |
| RPL28 | ribosomal protein L28 | -0.0307438 |
| LMO7 | LIM domain 7 | -0.0302465 |
| INHBA | inhibin, beta A | -0.0299345 |
| VDAC1 | voltage-dependent anion channel 1 | -0.029055 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0286622 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0283324 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.027989 |
| RPS3 | ribosomal protein S3 | -0.0275852 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0271811 |
| RPS27A | ribosomal protein S27a | -0.0268909 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0268145 |
| VCL | vinculin | -0.0267471 |
| RPS16 | ribosomal protein S16 | -0.0267434 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0267188 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.026659 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0262773 |
| TENM3 | teneurin transmembrane protein 3 | -0.0261955 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0259597 |
| RAI14 | retinoic acid induced 14 | -0.0259472 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0257943 |
| MAGT1 | magnesium transporter 1 | -0.0251959 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0251462 |
| PRKCA | protein kinase C, alpha | -0.025094 |
| RPS29 | ribosomal protein S29 | -0.0249775 |
| ATXN1 | ataxin 1 | -0.024752 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0244599 |
| PDE10A | phosphodiesterase 10A | -0.0244267 |
| CCDC14 | coiled-coil domain containing 14 | -0.0244231 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0241298 |
| RPS11 | ribosomal protein S11 | -0.0240806 |
| DEK | DEK proto-oncogene | -0.0238106 |
| ATM | ATM serine/threonine kinase | -0.0236133 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.023401 |
| POTEF | POTE ankyrin domain family, member F | -0.0231046 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.022987 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0228545 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0228412 |
| RPL9 | ribosomal protein L9 | -0.0226225 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0223676 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.02225 |
| COL5A1 | collagen, type V, alpha 1 | -0.022209 |
| RACK1 | receptor for activated C kinase 1 | -0.0219957 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0219812 |
| RPL38 | ribosomal protein L38 | -0.0219242 |
| FLNB | filamin B, beta | -0.0216602 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0216377 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0214746 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0214274 |
| TCF12 | transcription factor 12 | -0.0210052 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0209463 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0209261 |
| MCL1 | myeloid cell leukemia 1 | -0.020778 |
| RPS10 | ribosomal protein S10 | -0.0207068 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0206903 |
| RPL23 | ribosomal protein L23 | -0.0206666 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0204333 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0204048 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0201787 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0201165 |
| PYGL | phosphorylase, glycogen, liver | -0.0200094 |
| CHD6 | chromodomain helicase DNA binding protein 6 | -0.0199705 |
| RASAL2 | RAS protein activator like 2 | -0.0198869 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0198797 |
