| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capivasertib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capivasertib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0601309 |
| INTS6 | integrator complex subunit 6 | 0.0549571 |
| SMAD3 | SMAD family member 3 | 0.047545 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0388963 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0338394 |
| DSCAM | Down syndrome cell adhesion molecule | 0.033396 |
| PRKCA | protein kinase C, alpha | 0.0317927 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0309641 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0295642 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0285764 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0285344 |
| SMYD3 | SET and MYND domain containing 3 | 0.0264303 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0250662 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0239377 |
| PCNX4 | pecanex 4 | 0.0231003 |
| ANO6 | anoctamin 6 | 0.0225647 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0186239 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0183272 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.017938 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0175764 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0173639 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0173262 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0173082 |
| SIK2 | salt-inducible kinase 2 | 0.0172954 |
| ZNF638 | zinc finger protein 638 | 0.0171747 |
| NABP1 | nucleic acid binding protein 1 | 0.0170906 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0169717 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.016844 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0161519 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0160972 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0160386 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0157822 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0157567 |
| CAB39 | calcium binding protein 39 | 0.0155179 |
| WDR33 | WD repeat domain 33 | 0.015124 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0149743 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0148576 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0147607 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.014738 |
| NRDC | nardilysin convertase | 0.0147358 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0144532 |
| RCOR1 | REST corepressor 1 | 0.0142171 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0140691 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0139882 |
| NLRP1 | NLR family, pyrin domain containing 1 | 0.0139613 |
| MTMR3 | myotubularin related protein 3 | 0.0139529 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0139418 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0138056 |
| HPCAL1 | hippocalcin-like 1 | 0.0137961 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | 0.013552 |
| NOTCH2 | notch 2 | 0.0134462 |
| METTL15 | methyltransferase like 15 | 0.0134453 |
| GOSR2 | golgi SNAP receptor complex member 2 | 0.0132728 |
| MB21D2 | Mab-21 domain containing 2 | 0.0129578 |
| GLRX | glutaredoxin (thioltransferase) | 0.0129201 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0129028 |
| HLA-B | major histocompatibility complex, class I, B | 0.0128518 |
| PLPP1 | phospholipid phosphatase 1 | 0.0128277 |
| RBM12 | RNA binding motif protein 12 | 0.0128229 |
| ZNF655 | zinc finger protein 655 | 0.0127988 |
| JAK1 | Janus kinase 1 | 0.0127921 |
| STPG4 | sperm-tail PG-rich repeat containing 4 | 0.012639 |
| FAM177A1 | family with sequence similarity 177, member A1 | 0.012442 |
| FOXO1 | forkhead box O1 | 0.0124385 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0124312 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0124073 |
| RNF34 | ring finger protein 34, E3 ubiquitin protein ligase | 0.0123351 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0123215 |
| RPL3 | ribosomal protein L3 | 0.012298 |
| COL5A1 | collagen, type V, alpha 1 | 0.0122608 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 0.0121708 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0121116 |
| FKBP15 | FK506 binding protein 15, 133kDa | 0.0121012 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0120781 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0120678 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | 0.0120529 |
| CAPRIN2 | caprin family member 2 | 0.0120274 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0119157 |
| FNIP1 | folliculin interacting protein 1 | 0.0118819 |
| HDAC9 | histone deacetylase 9 | 0.011764 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0117298 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0115973 |
| RPS2 | ribosomal protein S2 | 0.0115767 |
| NPTN | neuroplastin | 0.0115306 |
| OPHN1 | oligophrenin 1 | 0.0115078 |
| BRD2 | bromodomain containing 2 | 0.0115005 |
| ELOVL7 | ELOVL fatty acid elongase 7 | 0.0114441 |
| GPC5 | glypican 5 | 0.011422 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0114064 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0113914 |
| ENSA | endosulfine alpha | 0.0113448 |
| GUK1 | guanylate kinase 1 | 0.0113291 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.011325 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0113179 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0112653 |
| HEATR5B | HEAT repeat containing 5B | 0.0111407 |
| OSBP2 | oxysterol binding protein 2 | 0.0110605 |
| TRIM24 | tripartite motif containing 24 | 0.0110552 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.011051 |
| AGRN | agrin | 0.0110175 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.232859 |
| VIM | vimentin | -0.206204 |
| TMSB10 | thymosin beta 10 | -0.142741 |
| PTMA | prothymosin, alpha | -0.121415 |
| LDHA | lactate dehydrogenase A | -0.0780406 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0762384 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0651746 |
| CD44 | CD44 molecule (Indian blood group) | -0.0643166 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0629027 |
| RBM39 | RNA binding motif protein 39 | -0.061769 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0604314 |
| PKM | pyruvate kinase, muscle | -0.0576981 |
| YBX3 | Y box binding protein 3 | -0.0538498 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0500112 |
| POTEF | POTE ankyrin domain family, member F | -0.049986 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0479456 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0470734 |
| DEK | DEK proto-oncogene | -0.046651 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0446775 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0441666 |
| NDRG1 | N-myc downstream regulated 1 | -0.0429151 |
| RPLP1 | ribosomal protein, large, P1 | -0.0427126 |
| IGF2 | insulin-like growth factor 2 | -0.0422489 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0394372 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0390824 |
| TPX2 | TPX2, microtubule-associated | -0.0390713 |
| TPM4 | tropomyosin 4 | -0.0390009 |
| MATR3 | matrin 3 | -0.0385518 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0382745 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0382529 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0360236 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0358817 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0356004 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0352543 |
| IER3 | immediate early response 3 | -0.0346165 |
| DIAPH3 | diaphanous-related formin 3 | -0.0336287 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0336028 |
| MT2A | metallothionein 2A | -0.0332902 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0332187 |
| MKI67 | marker of proliferation Ki-67 | -0.0331974 |
| RAD51B | RAD51 paralog B | -0.0328354 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0328069 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0324474 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0320182 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0319102 |
| TPI1 | triosephosphate isomerase 1 | -0.0318614 |
| CENPF | centromere protein F, 350/400kDa | -0.0318569 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0313226 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0310574 |
| TMEM123 | transmembrane protein 123 | -0.0310535 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0304971 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0303146 |
| TXNRD1 | thioredoxin reductase 1 | -0.0303035 |
| PGK1 | phosphoglycerate kinase 1 | -0.0302088 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0300536 |
| SETD5 | SET domain containing 5 | -0.0297488 |
| NF1 | neurofibromin 1 | -0.0297287 |
| TUBA1B | tubulin, alpha 1b | -0.0294427 |
| RPL7 | ribosomal protein L7 | -0.0292213 |
| ANXA2 | annexin A2 | -0.0289292 |
| NUP58 | nucleoporin 58 | -0.0287916 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0287809 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0287309 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0283951 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0278459 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0275424 |
| MAP1B | microtubule-associated protein 1B | -0.0275199 |
| CCNI | cyclin I | -0.0274236 |
| ANXA1 | annexin A1 | -0.027355 |
| RPL35A | ribosomal protein L35a | -0.027283 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0272212 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0271206 |
| SPAG9 | sperm associated antigen 9 | -0.027112 |
| RTN4 | reticulon 4 | -0.0269831 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0269829 |
| DNER | delta/notch-like EGF repeat containing | -0.0268416 |
| RPS13 | ribosomal protein S13 | -0.0266697 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0266684 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0263208 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0263101 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0261998 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0261625 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0261365 |
| RPLP0 | ribosomal protein, large, P0 | -0.0259561 |
| FTL | ferritin, light polypeptide | -0.0258756 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0258578 |
| WAC | WW domain containing adaptor with coiled-coil | -0.025808 |
| MTDH | metadherin | -0.0257452 |
| EGR1 | early growth response 1 | -0.025694 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0254478 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0252376 |
| RPS23 | ribosomal protein S23 | -0.0251977 |
| PRR11 | proline rich 11 | -0.0251929 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0251897 |
| SEPTIN7 | septin 7 | -0.0244721 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0244151 |
| TPR | translocated promoter region, nuclear basket protein | -0.0243202 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0240506 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0237803 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0237743 |
