| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capmatinib perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capmatinib_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.289708 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.123857 |
| PODXL | podocalyxin-like | 0.10268 |
| CDH13 | cadherin 13 | 0.0894965 |
| CALR | calreticulin | 0.0833715 |
| HDAC9 | histone deacetylase 9 | 0.0716418 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0714791 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0678621 |
| S100A10 | S100 calcium binding protein A10 | 0.0590907 |
| DST | dystonin | 0.0582602 |
| LDHA | lactate dehydrogenase A | 0.0580535 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0564691 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0547321 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0524929 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.050905 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0508138 |
| COL5A1 | collagen, type V, alpha 1 | 0.047856 |
| CSTB | cystatin B (stefin B) | 0.0476229 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0472506 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0462349 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0447382 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0446562 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0438129 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0431224 |
| RND3 | Rho family GTPase 3 | 0.0427905 |
| LMNA | lamin A/C | 0.0427779 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0422161 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0420289 |
| SQSTM1 | sequestosome 1 | 0.0406292 |
| PTMA | prothymosin, alpha | 0.0402584 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0390884 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0387204 |
| NDRG1 | N-myc downstream regulated 1 | 0.038371 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0381568 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0381035 |
| CANX | calnexin | 0.0365055 |
| BCL2L1 | BCL2-like 1 | 0.0360244 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0339552 |
| NAV2 | neuron navigator 2 | 0.0333115 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0327183 |
| RPL37A | ribosomal protein L37a | 0.031973 |
| FLNA | filamin A, alpha | 0.0306491 |
| FLNB | filamin B, beta | 0.0295376 |
| FSTL1 | follistatin-like 1 | 0.0293653 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0291453 |
| EGFR | epidermal growth factor receptor | 0.0287235 |
| ANXA1 | annexin A1 | 0.0274482 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0271825 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0271129 |
| DSPP | dentin sialophosphoprotein | 0.0267949 |
| TLE4 | transducin-like enhancer of split 4 | 0.0266597 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0261485 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0247913 |
| ANKRD30B | ankyrin repeat domain 30B | 0.0247613 |
| TPM4 | tropomyosin 4 | 0.0243297 |
| RASAL2 | RAS protein activator like 2 | 0.0238698 |
| APP | amyloid beta (A4) precursor protein | 0.0235439 |
| FMN2 | formin 2 | 0.0232606 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0231664 |
| SP100 | SP100 nuclear antigen | 0.0226279 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0225542 |
| RPS3 | ribosomal protein S3 | 0.0224235 |
| INTS6 | integrator complex subunit 6 | 0.0223763 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0223392 |
| ENO1 | enolase 1, (alpha) | 0.022242 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0217067 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0214357 |
| CYTH3 | cytohesin 3 | 0.0213892 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0213631 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.021104 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0207616 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0205193 |
| KRT18 | keratin 18, type I | 0.0204897 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0203973 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.020123 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0199624 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0198686 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0198028 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0196245 |
| ACTN1 | actinin, alpha 1 | 0.0195452 |
| ACTG1 | actin gamma 1 | 0.0195304 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.019522 |
| PKM | pyruvate kinase, muscle | 0.0193658 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0193411 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0193045 |
| ASPH | aspartate beta-hydroxylase | 0.0192865 |
| TUFT1 | tuftelin 1 | 0.0192605 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0192502 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0192117 |
| RPS12 | ribosomal protein S12 | 0.0191784 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) | 0.0191176 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0190076 |
| ERBIN | erbb2 interacting protein | 0.0189132 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0188315 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0186594 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0184674 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.0182107 |
| RPS2 | ribosomal protein S2 | 0.0181605 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0181221 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0181144 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.251936 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.194927 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.190049 |
| LOX | lysyl oxidase | -0.174515 |
| FBN1 | fibrillin 1 | -0.139929 |
| VIM | vimentin | -0.103633 |
| PLAT | plasminogen activator, tissue | -0.100079 |
| COL1A2 | collagen, type I, alpha 2 | -0.0918794 |
| MT2A | metallothionein 2A | -0.089408 |
| NAV1 | neuron navigator 1 | -0.0884314 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0859373 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0820288 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0818999 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0788671 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0763655 |
| CD44 | CD44 molecule (Indian blood group) | -0.0762412 |
| LOXL2 | lysyl oxidase-like 2 | -0.0751453 |
| COL5A2 | collagen, type V, alpha 2 | -0.0741752 |
| STC1 | stanniocalcin 1 | -0.0686272 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0653523 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0649854 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0612237 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0563238 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0559245 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0551561 |
| MX2 | MX dynamin-like GTPase 2 | -0.0546439 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0525332 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0519924 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.050686 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0498877 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.04861 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.048556 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0474948 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0466619 |
| GLIS3 | GLIS family zinc finger 3 | -0.0452971 |
| SP3 | Sp3 transcription factor | -0.0451648 |
| SUCNR1 | succinate receptor 1 | -0.0437996 |
| FRMD4A | FERM domain containing 4A | -0.0423466 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0418953 |
| UBC | ubiquitin C | -0.0410278 |
| THBS2 | thrombospondin 2 | -0.0400347 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.037188 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.036848 |
| PRSS23 | protease, serine, 23 | -0.0366858 |
| ANXA2 | annexin A2 | -0.0355704 |
| SBF2 | SET binding factor 2 | -0.0354751 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0353453 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0351796 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0347274 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0341728 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0337841 |
| TAGLN2 | transgelin 2 | -0.033657 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0329956 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0329044 |
| MYADM | myeloid-associated differentiation marker | -0.0327584 |
| GPC6 | glypican 6 | -0.0316592 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0308468 |
| RUNX1 | runt-related transcription factor 1 | -0.0305583 |
| RTN4 | reticulon 4 | -0.0304174 |
| TMSB10 | thymosin beta 10 | -0.0293233 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0293026 |
| EHBP1 | EH domain binding protein 1 | -0.029293 |
| SVIL | supervillin | -0.0290508 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0290028 |
| ATP13A3 | ATPase type 13A3 | -0.0283463 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0280759 |
| TMOD1 | tropomodulin 1 | -0.0278228 |
| COL3A1 | collagen, type III, alpha 1 | -0.0276416 |
| AFAP1 | actin filament associated protein 1 | -0.0276217 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0274684 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0274129 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0273739 |
| AUTS2 | autism susceptibility candidate 2 | -0.0268972 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0266983 |
| PXDN | peroxidasin | -0.0265859 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0264201 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0261294 |
| FRMD5 | FERM domain containing 5 | -0.025779 |
| OGA | O-GlcNAcase | -0.025592 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0252649 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0249573 |
| CLU | clusterin | -0.0244767 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0244155 |
| CD99 | CD99 molecule | -0.0244012 |
| MTSS1 | metastasis suppressor 1 | -0.0241458 |
| PGK1 | phosphoglycerate kinase 1 | -0.0241394 |
| MT1X | metallothionein 1X | -0.0234074 |
| B2M | beta-2-microglobulin | -0.0233805 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0231156 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0231025 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0228234 |
| WTAP | Wilms tumor 1 associated protein | -0.0223667 |
| TDRD7 | tudor domain containing 7 | -0.0218379 |
| LRRC49 | leucine rich repeat containing 49 | -0.0215512 |
| RNF145 | ring finger protein 145 | -0.0215171 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0213571 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0213197 |
| JAZF1 | JAZF zinc finger 1 | -0.0212118 |
| SDC4 | syndecan 4 | -0.021031 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0209603 |
