| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capmatinib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capmatinib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.144071 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.139946 |
| TLE4 | transducin-like enhancer of split 4 | 0.117802 |
| PLPP1 | phospholipid phosphatase 1 | 0.101674 |
| FMN1 | formin 1 | 0.098351 |
| RNF213 | ring finger protein 213 | 0.0913204 |
| LSAMP | limbic system-associated membrane protein | 0.0904369 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0831616 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0691809 |
| RIGI | RNA sensor RIG-I | 0.0645747 |
| GLCCI1 | glucocorticoid induced 1 | 0.0612984 |
| TPM1 | tropomyosin 1 (alpha) | 0.0602345 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0588512 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0537702 |
| SYNPO2 | synaptopodin 2 | 0.052962 |
| PDE10A | phosphodiesterase 10A | 0.0500214 |
| FERMT2 | fermitin family member 2 | 0.0480925 |
| STK38L | serine/threonine kinase 38 like | 0.0476119 |
| LPIN1 | lipin 1 | 0.0461816 |
| RPS12 | ribosomal protein S12 | 0.0460775 |
| KLHL13 | kelch-like family member 13 | 0.045404 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0433743 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0431965 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0430328 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0416759 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0414493 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.040509 |
| MYO1E | myosin IE | 0.0403943 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0403057 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0402189 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0397604 |
| MRTFA | myocardin related transcription factor A | 0.039126 |
| SIK2 | salt-inducible kinase 2 | 0.0389156 |
| TPM4 | tropomyosin 4 | 0.0384573 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0381147 |
| SP100 | SP100 nuclear antigen | 0.0379248 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0377254 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.037232 |
| FAM107B | family with sequence similarity 107, member B | 0.0370019 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0369407 |
| INTS6 | integrator complex subunit 6 | 0.0366356 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0361932 |
| SMYD3 | SET and MYND domain containing 3 | 0.0358937 |
| DST | dystonin | 0.0352088 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0351209 |
| ZNF804A | zinc finger protein 804A | 0.0345852 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.033842 |
| MX2 | MX dynamin-like GTPase 2 | 0.0335142 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0333425 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0332318 |
| AOPEP | aminopeptidase O (putative) | 0.033212 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0329256 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0315454 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0314441 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0309992 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0308603 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0298488 |
| TCF12 | transcription factor 12 | 0.0293936 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0293789 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0293084 |
| VMP1 | vacuole membrane protein 1 | 0.0292693 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0291859 |
| GPHN | gephyrin | 0.0290589 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0289867 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0288044 |
| NFIB | nuclear factor I/B | 0.0287932 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0287316 |
| MED13 | mediator complex subunit 13 | 0.0286057 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0278833 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.027479 |
| ACTN4 | actinin, alpha 4 | 0.0273907 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0272094 |
| STXBP4 | syntaxin binding protein 4 | 0.0272045 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0271796 |
| CUL3 | cullin 3 | 0.0270227 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0269188 |
| TUFT1 | tuftelin 1 | 0.0267129 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0264827 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0263018 |
| LMO7 | LIM domain 7 | 0.0262079 |
| RALYL | RALY RNA binding protein-like | 0.0261328 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0260964 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0258782 |
| AUTS2 | autism susceptibility candidate 2 | 0.0256052 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0254296 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0253069 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0252005 |
| FOXO3 | forkhead box O3 | 0.0250725 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0247949 |
| MED13L | mediator complex subunit 13-like | 0.0247826 |
| CREBBP | CREB binding protein | 0.024615 |
| PLSCR1 | phospholipid scramblase 1 | 0.0243768 |
| HOMER1 | homer scaffolding protein 1 | 0.0243251 |
| STOX2 | storkhead box 2 | 0.0242887 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0242442 |
| AHNAK | AHNAK nucleoprotein | 0.0241083 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0238999 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0236978 |
| SYT1 | synaptotagmin I | 0.0236696 |
| HDX | highly divergent homeobox | 0.0236681 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.337885 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.30764 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.206004 |
| NRG1 | neuregulin 1 | -0.128426 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.11586 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.101398 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0857259 |
| PLAT | plasminogen activator, tissue | -0.0819424 |
| VIM | vimentin | -0.0758519 |
| FAM13A | family with sequence similarity 13, member A | -0.0691852 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0687288 |
| MEF2A | myocyte enhancer factor 2A | -0.0662408 |
| GDF15 | growth differentiation factor 15 | -0.0576639 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0555026 |
| PTMA | prothymosin, alpha | -0.0552922 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0535144 |
| GPC5 | glypican 5 | -0.0515726 |
| STC1 | stanniocalcin 1 | -0.0509018 |
| MAP1B | microtubule-associated protein 1B | -0.0499356 |
| NDRG1 | N-myc downstream regulated 1 | -0.04881 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0473911 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0443558 |
| WDR45B | WD repeat domain 45B | -0.0425961 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0416207 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.041599 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0412627 |
| GOLGA4 | golgin A4 | -0.0407872 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0401059 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.039152 |
| CENPF | centromere protein F, 350/400kDa | -0.038891 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0388877 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0387897 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.038747 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0369104 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0353493 |
| SETD5 | SET domain containing 5 | -0.0349317 |
| DPH6 | diphthamine biosynthesis 6 | -0.0349216 |
| PGK1 | phosphoglycerate kinase 1 | -0.0339862 |
| ZNF292 | zinc finger protein 292 | -0.0333934 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0323996 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0320038 |
| SCG2 | secretogranin II | -0.0318716 |
| PKM | pyruvate kinase, muscle | -0.0316224 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0311676 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0310105 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0307883 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0306827 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0305878 |
| HMGA1 | high mobility group AT-hook 1 | -0.0302971 |
| FNBP1 | formin binding protein 1 | -0.0301495 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.029713 |
| RHOA | ras homolog family member A | -0.0295391 |
| AHR | aryl hydrocarbon receptor | -0.0294485 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0294287 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0291078 |
| ATRNL1 | attractin-like 1 | -0.0290258 |
| HMGA2 | high mobility group AT-hook 2 | -0.0285506 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0285473 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0283369 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0280004 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0278387 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0277367 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0274568 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0273281 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0272655 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0270175 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0264866 |
| ANGPT1 | angiopoietin 1 | -0.0263615 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0259492 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0253102 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0250015 |
| SMC4 | structural maintenance of chromosomes 4 | -0.024994 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0245905 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0242934 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0242746 |
| COL1A1 | collagen, type I, alpha 1 | -0.023952 |
| BSG | basigin (Ok blood group) | -0.0236587 |
| FRMD4A | FERM domain containing 4A | -0.0236581 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0235705 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0232646 |
| COPA | coatomer protein complex, subunit alpha | -0.0231344 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0231024 |
| RTN4 | reticulon 4 | -0.0230843 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0229822 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0228448 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0228208 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.0223677 |
| MTSS2 | MTSS I-BAR domain containing 2 | -0.0223221 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0221934 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0220624 |
| DIAPH2 | diaphanous-related formin 2 | -0.0219802 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0219641 |
| TPR | translocated promoter region, nuclear basket protein | -0.0218823 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0217561 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0216395 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0215746 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0215278 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0214813 |
| OGA | O-GlcNAcase | -0.0214578 |
| S100A6 | S100 calcium binding protein A6 | -0.0214195 |
