| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capmatinib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capmatinib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RNF213 | ring finger protein 213 | 0.101375 |
| LCN2 | lipocalin 2 | 0.0941557 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0906575 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0866574 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0759042 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0696627 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0694265 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0676399 |
| INTS6 | integrator complex subunit 6 | 0.0657833 |
| SMAD3 | SMAD family member 3 | 0.065103 |
| DST | dystonin | 0.057319 |
| PDZD8 | PDZ domain containing 8 | 0.056385 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0545123 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0533585 |
| PLSCR2 | phospholipid scramblase 2 | 0.053163 |
| HKDC1 | hexokinase domain containing 1 | 0.0472631 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0466321 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0461185 |
| LMO7 | LIM domain 7 | 0.0451521 |
| SP100 | SP100 nuclear antigen | 0.0443182 |
| MX1 | MX dynamin-like GTPase 1 | 0.0372525 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0363822 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0359519 |
| VCL | vinculin | 0.0348418 |
| KYNU | kynureninase | 0.0347097 |
| MYO5B | myosin VB | 0.0344781 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.034438 |
| MX2 | MX dynamin-like GTPase 2 | 0.0344336 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0339506 |
| DPP4 | dipeptidyl-peptidase 4 | 0.033887 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0309893 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0296076 |
| SERINC5 | serine incorporator 5 | 0.0292803 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0291475 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0287319 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0283539 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0279049 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0277583 |
| IFNGR1 | interferon gamma receptor 1 | 0.027747 |
| MCU | mitochondrial calcium uniporter | 0.0277287 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.027181 |
| SIK3 | SIK family kinase 3 | 0.0271614 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0269452 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.026894 |
| APP | amyloid beta (A4) precursor protein | 0.0258756 |
| YAP1 | Yes-associated protein 1 | 0.0258626 |
| CREBBP | CREB binding protein | 0.0255879 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0254668 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0250287 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0249438 |
| ASPH | aspartate beta-hydroxylase | 0.02491 |
| TJP1 | tight junction protein 1 | 0.0247647 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0246289 |
| SMYD3 | SET and MYND domain containing 3 | 0.0244398 |
| POF1B | premature ovarian failure, 1B | 0.0242547 |
| WWOX | WW domain containing oxidoreductase | 0.0241565 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0239171 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0238055 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0237921 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0236976 |
| BCL2L1 | BCL2-like 1 | 0.0236633 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0230936 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0224161 |
| TXNRD1 | thioredoxin reductase 1 | 0.022108 |
| LIMA1 | LIM domain and actin binding 1 | 0.0220575 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0219095 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0219068 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0218646 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0218563 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0218251 |
| CLOCK | clock circadian regulator | 0.0217318 |
| ACTN1 | actinin, alpha 1 | 0.0217236 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0216841 |
| TUFT1 | tuftelin 1 | 0.0214797 |
| MAP7 | microtubule-associated protein 7 | 0.0213232 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0213034 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0212594 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0210416 |
| TMEM65 | transmembrane protein 65 | 0.0208644 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0205057 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0203307 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0200148 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0199888 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0196789 |
| JMJD1C | jumonji domain containing 1C | 0.0196003 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0195416 |
| MED13 | mediator complex subunit 13 | 0.0194024 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0193995 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0193332 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0191294 |
| SET | SET nuclear proto-oncogene | 0.0188157 |
| RPS3 | ribosomal protein S3 | 0.0187338 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0183614 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0182939 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0182867 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0178122 |
| USP54 | ubiquitin specific peptidase 54 | 0.0177334 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0177101 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0171537 |
| FTL | ferritin, light polypeptide | 0.0170722 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.180258 |
| EGR1 | early growth response 1 | -0.168945 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.160987 |
| B2M | beta-2-microglobulin | -0.140042 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.120764 |
| EZR | ezrin | -0.117445 |
| H1-0 | H1.0 linker histone | -0.104054 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0981306 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0954807 |
| NDRG1 | N-myc downstream regulated 1 | -0.0928978 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0888745 |
| ITGA6 | integrin, alpha 6 | -0.0872829 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0844872 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0839372 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0825716 |
| SQSTM1 | sequestosome 1 | -0.0803532 |
| TXNIP | thioredoxin interacting protein | -0.0769122 |
| ANXA2 | annexin A2 | -0.076276 |
| PRKCA | protein kinase C, alpha | -0.0758871 |
| LYZ | lysozyme | -0.0742211 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0738576 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0714791 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0714739 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0705826 |
| CCNL1 | cyclin L1 | -0.0700227 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0696003 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0680048 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.066962 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0645762 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0639253 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0630876 |
| HLA-B | major histocompatibility complex, class I, B | -0.062559 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0624722 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0604965 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0592434 |
| IRF1 | interferon regulatory factor 1 | -0.0553548 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0547548 |
| ABHD2 | abhydrolase domain containing 2 | -0.0530053 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0527894 |
| PTMA | prothymosin, alpha | -0.0523056 |
| AHI1 | Abelson helper integration site 1 | -0.0518841 |
| NPSR1 | neuropeptide S receptor 1 | -0.0514649 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0509155 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0508965 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0502064 |
| HLA-E | major histocompatibility complex, class I, E | -0.047883 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0463496 |
| S100A6 | S100 calcium binding protein A6 | -0.0455748 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0453929 |
| ABLIM1 | actin binding LIM protein 1 | -0.0449652 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0448001 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.044688 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0443407 |
| WDR45B | WD repeat domain 45B | -0.0438298 |
| RBM39 | RNA binding motif protein 39 | -0.0430992 |
| RNF149 | ring finger protein 149 | -0.0421318 |
| PERP | PERP, TP53 apoptosis effector | -0.0420745 |
| PTEN | phosphatase and tensin homolog | -0.0419369 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0413453 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.041132 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0406425 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0395929 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0394971 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0393862 |
| PLSCR1 | phospholipid scramblase 1 | -0.0390191 |
| RUNX1 | runt-related transcription factor 1 | -0.0387787 |
| PKM | pyruvate kinase, muscle | -0.0384739 |
| SSH2 | slingshot protein phosphatase 2 | -0.037856 |
| ATP11A | ATPase, class VI, type 11A | -0.0378167 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0376701 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.03737 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0366792 |
| ADIPOR2 | adiponectin receptor 2 | -0.0365497 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0365069 |
| AGR2 | anterior gradient 2 | -0.035913 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0355892 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0353949 |
| HLA-A | major histocompatibility complex, class I, A | -0.0351979 |
| FDPS | farnesyl diphosphate synthase | -0.0351927 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0351199 |
| SPATA13 | spermatogenesis associated 13 | -0.0350055 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0348651 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0346336 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0345755 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0343953 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0343311 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.034331 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0339865 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0338714 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0338168 |
| ZNF395 | zinc finger protein 395 | -0.0330241 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0329362 |
| JUN | jun proto-oncogene | -0.0328408 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0327673 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0327655 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0325883 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0325317 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0319537 |
| MXD1 | MAX dimerization protein 1 | -0.0319125 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.031906 |
