| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capmatinib perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capmatinib_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.163439 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0729558 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0581911 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0539573 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0510618 |
| CALR | calreticulin | 0.0473812 |
| STC1 | stanniocalcin 1 | 0.0448474 |
| APP | amyloid beta (A4) precursor protein | 0.038511 |
| ARRDC3 | arrestin domain containing 3 | 0.0363604 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0331242 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0331183 |
| TMSB10 | thymosin beta 10 | 0.0329676 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0309282 |
| RPS8 | ribosomal protein S8 | 0.0300812 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0286657 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0284019 |
| VEGFA | vascular endothelial growth factor A | 0.0278651 |
| LDHA | lactate dehydrogenase A | 0.0272301 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0257243 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0247884 |
| RPS4X | ribosomal protein S4, X-linked | 0.0238035 |
| RPS6 | ribosomal protein S6 | 0.0225182 |
| RPL5 | ribosomal protein L5 | 0.0223485 |
| YBX1 | Y box binding protein 1 | 0.0215743 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0207406 |
| CLIC4 | chloride intracellular channel 4 | 0.0204931 |
| HMGA2 | high mobility group AT-hook 2 | 0.0202459 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0201384 |
| RACK1 | receptor for activated C kinase 1 | 0.0201358 |
| RPL12 | ribosomal protein L12 | 0.0200423 |
| JMJD1C | jumonji domain containing 1C | 0.0197968 |
| MT1X | metallothionein 1X | 0.0196884 |
| RPS2 | ribosomal protein S2 | 0.0193718 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0192157 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0190577 |
| RPL36 | ribosomal protein L36 | 0.0190339 |
| RPL23 | ribosomal protein L23 | 0.0183908 |
| CD44 | CD44 molecule (Indian blood group) | 0.0182931 |
| RPL8 | ribosomal protein L8 | 0.0179959 |
| S100A9 | S100 calcium binding protein A9 | 0.0179606 |
| SDF4 | stromal cell derived factor 4 | 0.0175307 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0170743 |
| LAMB1 | laminin, beta 1 | 0.0169007 |
| SVIL | supervillin | 0.0167406 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0165631 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0165037 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0164198 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0160158 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0159854 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0157216 |
| IFI44 | interferon-induced protein 44 | 0.0153457 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0153215 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0152414 |
| PCBP2 | poly(rC) binding protein 2 | 0.0151874 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0151642 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0150335 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.014961 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0147154 |
| TUBB | tubulin, beta class I | 0.0146883 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0143815 |
| RBM25 | RNA binding motif protein 25 | 0.0143507 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0143357 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0142998 |
| SIK3 | SIK family kinase 3 | 0.0142931 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0141941 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0141422 |
| FAM107B | family with sequence similarity 107, member B | 0.0139177 |
| MLF1 | myeloid leukemia factor 1 | 0.013917 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0138629 |
| ATL1 | atlastin GTPase 1 | 0.0136865 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0135876 |
| SFTPA2 | surfactant protein A2 | 0.0135059 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0133462 |
| RPL7 | ribosomal protein L7 | 0.0132525 |
| RPL7A | ribosomal protein L7a | 0.0130862 |
| CSPP1 | centrosome and spindle pole associated protein 1 | 0.0129192 |
| MATR3 | matrin 3 | 0.0126738 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0126504 |
| RPL18 | ribosomal protein L18 | 0.0123857 |
| ACTN1 | actinin, alpha 1 | 0.0123819 |
| DUSP6 | dual specificity phosphatase 6 | 0.0122948 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0120585 |
| DSTN | destrin (actin depolymerizing factor) | 0.0120549 |
| RPS12 | ribosomal protein S12 | 0.0119418 |
| RPL35 | ribosomal protein L35 | 0.0117864 |
| NUP153 | nucleoporin 153kDa | 0.011736 |
| MED15 | mediator complex subunit 15 | 0.0117345 |
| SRPK2 | SRSF protein kinase 2 | 0.0116982 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0116458 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0116331 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0113906 |
| GBP4 | guanylate binding protein 4 | 0.0112607 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0112466 |
| ECE1 | endothelin converting enzyme 1 | 0.0112417 |
| HAS2 | hyaluronan synthase 2 | 0.0111414 |
| NRP1 | neuropilin 1 | 0.0110831 |
| VIM | vimentin | 0.0110211 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0108883 |
| LUZP1 | leucine zipper protein 1 | 0.0107852 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0107751 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.29459 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.231782 |
| COL1A1 | collagen, type I, alpha 1 | -0.137158 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.128033 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.115868 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.101564 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0912157 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0869648 |
| CDH13 | cadherin 13 | -0.0806445 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0769071 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0685658 |
| LOX | lysyl oxidase | -0.0650934 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0631548 |
| FBN1 | fibrillin 1 | -0.061629 |
| COL5A1 | collagen, type V, alpha 1 | -0.0615583 |
| COL1A2 | collagen, type I, alpha 2 | -0.0596288 |
| NDRG1 | N-myc downstream regulated 1 | -0.0563849 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0558384 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0530784 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0528648 |
| LOXL2 | lysyl oxidase-like 2 | -0.0512826 |
| TPM4 | tropomyosin 4 | -0.0509561 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0507211 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0502258 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0472531 |
| PRELID2 | PRELI domain containing 2 | -0.0450674 |
| DST | dystonin | -0.0441098 |
| CALD1 | caldesmon 1 | -0.0420519 |
| ATXN1 | ataxin 1 | -0.0419935 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0403377 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0399237 |
| CADM1 | cell adhesion molecule 1 | -0.0367969 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0360087 |
| IER3 | immediate early response 3 | -0.0359325 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0357419 |
| ACTG1 | actin gamma 1 | -0.0354698 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0353467 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0351001 |
| AHNAK | AHNAK nucleoprotein | -0.0344608 |
| CAVIN1 | caveolae associated protein 1 | -0.0335109 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0324004 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0314062 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0313581 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0293211 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0288098 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0284205 |
| SEC24D | SEC24 family member D | -0.0281299 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0279363 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0277106 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0276325 |
| PGK1 | phosphoglycerate kinase 1 | -0.0275351 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0274394 |
| CA12 | carbonic anhydrase XII | -0.0274157 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0272738 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0271424 |
| BBX | bobby sox homolog (Drosophila) | -0.0271048 |
| CNTN5 | contactin 5 | -0.0267786 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0267354 |
| CD109 | CD109 molecule | -0.0267099 |
| MTDH | metadherin | -0.0264333 |
| STC2 | stanniocalcin 2 | -0.0262637 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.026174 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0259517 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0258 |
| TENM3 | teneurin transmembrane protein 3 | -0.0255899 |
| CANX | calnexin | -0.0253086 |
| GOLGA4 | golgin A4 | -0.0252845 |
| VCAN | versican | -0.0250697 |
| OXR1 | oxidation resistance 1 | -0.0244147 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0243581 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0241059 |
| PDE10A | phosphodiesterase 10A | -0.0234464 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0232204 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0231094 |
| CMIP | c-Maf inducing protein | -0.0230878 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0230228 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0229079 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0228542 |
| HYOU1 | hypoxia up-regulated 1 | -0.0227232 |
| IL6ST | interleukin 6 signal transducer | -0.0222615 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0222571 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0221113 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0218228 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0215493 |
| EGR1 | early growth response 1 | -0.0215275 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0213537 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0213111 |
| SQSTM1 | sequestosome 1 | -0.0207379 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0206155 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0206007 |
| SYNJ2 | synaptojanin 2 | -0.0205057 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0202007 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0201084 |
| RUNX1 | runt-related transcription factor 1 | -0.0200229 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.020005 |
| FBXO32 | F-box protein 32 | -0.0197276 |
| TMSB4X | thymosin beta 4, X-linked | -0.0195645 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0194349 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0194103 |
| YEATS2 | YEATS domain containing 2 | -0.0193975 |
