| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capmatinib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capmatinib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD9 | sterile alpha motif domain containing 9 | 0.0844707 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.067154 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0668738 |
| LMO7 | LIM domain 7 | 0.0633392 |
| SULF1 | sulfatase 1 | 0.0600051 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.056682 |
| KRT17 | keratin 17, type I | 0.0544223 |
| CLU | clusterin | 0.0541801 |
| IFI44L | interferon-induced protein 44-like | 0.0520145 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0495203 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0456643 |
| DOK5 | docking protein 5 | 0.044908 |
| FOXO1 | forkhead box O1 | 0.0445771 |
| TXNIP | thioredoxin interacting protein | 0.042764 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0412968 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0403672 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0401952 |
| MEF2A | myocyte enhancer factor 2A | 0.0399929 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0392114 |
| RIGI | RNA sensor RIG-I | 0.038543 |
| LDHA | lactate dehydrogenase A | 0.0385396 |
| NEK7 | NIMA-related kinase 7 | 0.0382253 |
| MX1 | MX dynamin-like GTPase 1 | 0.0380105 |
| MYOF | myoferlin | 0.0378313 |
| EHF | ets homologous factor | 0.0375162 |
| MEF2C | myocyte enhancer factor 2C | 0.0365149 |
| PALLD | palladin, cytoskeletal associated protein | 0.035061 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0336138 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0326057 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0322285 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0321537 |
| AOPEP | aminopeptidase O (putative) | 0.0315572 |
| MX2 | MX dynamin-like GTPase 2 | 0.0315568 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0315274 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0314535 |
| NRG1 | neuregulin 1 | 0.0312488 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0311609 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0307198 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.030683 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0306649 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0305718 |
| MSN | moesin | 0.030214 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0297188 |
| ANXA1 | annexin A1 | 0.0295814 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0294342 |
| ARRDC3 | arrestin domain containing 3 | 0.0290254 |
| KRT6A | keratin 6A, type II | 0.0286569 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.0285679 |
| FOXP1 | forkhead box P1 | 0.0276818 |
| MECOM | MDS1 and EVI1 complex locus | 0.0275586 |
| SEPTIN9 | septin 9 | 0.0275197 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0274385 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0273057 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0269905 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0266278 |
| BCL2L1 | BCL2-like 1 | 0.0265216 |
| MT1E | metallothionein 1E | 0.0261895 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0261511 |
| VPS35 | vacuolar protein sorting 35 homolog (S. cerevisiae) | 0.0259997 |
| TJP1 | tight junction protein 1 | 0.0257234 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0255675 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0253083 |
| APP | amyloid beta (A4) precursor protein | 0.0252517 |
| GBP4 | guanylate binding protein 4 | 0.0250888 |
| STAG2 | stromal antigen 2 | 0.0249511 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0248787 |
| OSMR | oncostatin M receptor | 0.0247484 |
| IFI44 | interferon-induced protein 44 | 0.0242878 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0239881 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.0237271 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0236781 |
| PLPP6 | phospholipid phosphatase 6 | 0.023674 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0235861 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0235792 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0232539 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0231905 |
| PLPP1 | phospholipid phosphatase 1 | 0.0230566 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0229743 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0225254 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0223757 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.022212 |
| JAG1 | jagged 1 | 0.021864 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0215755 |
| PLAT | plasminogen activator, tissue | 0.0215442 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.021541 |
| DSPP | dentin sialophosphoprotein | 0.0210609 |
| RPS4X | ribosomal protein S4, X-linked | 0.0207708 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0207244 |
| TAGLN2 | transgelin 2 | 0.0206639 |
| PCM1 | pericentriolar material 1 | 0.0205706 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa | 0.020487 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0204489 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0202096 |
| TXNRD1 | thioredoxin reductase 1 | 0.0199129 |
| RLIM | ring finger protein, LIM domain interacting | 0.0198432 |
| YBX3 | Y box binding protein 3 | 0.0197077 |
| TGM2 | transglutaminase 2 | 0.0196319 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.0195025 |
| PTK2 | protein tyrosine kinase 2 | 0.0194472 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0192145 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.216231 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0983328 |
| MTSS1 | metastasis suppressor 1 | -0.0970101 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0921801 |
| RPL35A | ribosomal protein L35a | -0.0913352 |
| RPLP1 | ribosomal protein, large, P1 | -0.0842807 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0823089 |
| STC1 | stanniocalcin 1 | -0.0811277 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0730242 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0712278 |
| HMGA2 | high mobility group AT-hook 2 | -0.0707172 |
| INTS6 | integrator complex subunit 6 | -0.0652856 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0627732 |
| BLCAP | bladder cancer associated protein | -0.0621949 |
| RPLP2 | ribosomal protein, large, P2 | -0.0604839 |
| RPS24 | ribosomal protein S24 | -0.0598243 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0570838 |
| HM13 | histocompatibility (minor) 13 | -0.0568956 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0560477 |
| RPL36A | ribosomal protein L36a | -0.0555835 |
| CAVIN1 | caveolae associated protein 1 | -0.0553855 |
| RPS25 | ribosomal protein S25 | -0.0540499 |
| RPS13 | ribosomal protein S13 | -0.051844 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0509511 |
| EGR1 | early growth response 1 | -0.0506644 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0503684 |
| RPL31 | ribosomal protein L31 | -0.0491014 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0489695 |
| TMSB10 | thymosin beta 10 | -0.0484953 |
| HLA-B | major histocompatibility complex, class I, B | -0.0478091 |
| RPS21 | ribosomal protein S21 | -0.0477738 |
| RPL34 | ribosomal protein L34 | -0.0465846 |
| ANXA2 | annexin A2 | -0.0461998 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0454545 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0453905 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0445668 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0439072 |
| GNAS | GNAS complex locus | -0.0424474 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.0405377 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0398941 |
| S100A10 | S100 calcium binding protein A10 | -0.0398653 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0397582 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0388596 |
| RPS27A | ribosomal protein S27a | -0.038793 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0372988 |
| RPL37A | ribosomal protein L37a | -0.0369199 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0364164 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.035868 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0354791 |
| RPS27 | ribosomal protein S27 | -0.0353787 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0352792 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0351344 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0349759 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0348883 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0348659 |
| CUX1 | cut-like homeobox 1 | -0.0343618 |
| RUNX1 | runt-related transcription factor 1 | -0.0338701 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0337937 |
| ANKRD11 | ankyrin repeat domain 11 | -0.033563 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0334068 |
| IER3 | immediate early response 3 | -0.0329633 |
| FLNB | filamin B, beta | -0.0325942 |
| RPL12 | ribosomal protein L12 | -0.0319351 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0318699 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0318292 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0314013 |
| NUMB | numb homolog (Drosophila) | -0.0308525 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0305684 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0303774 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0303055 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0302281 |
| RAI14 | retinoic acid induced 14 | -0.0301094 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0299691 |
| CMIP | c-Maf inducing protein | -0.0297669 |
| RAD51B | RAD51 paralog B | -0.0295777 |
| ACTG1 | actin gamma 1 | -0.0294999 |
| NAV2 | neuron navigator 2 | -0.0294449 |
| CTBP2 | C-terminal binding protein 2 | -0.0292372 |
| CDK6 | cyclin-dependent kinase 6 | -0.0284928 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0282379 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0280306 |
| KIAA1217 | KIAA1217 | -0.0278038 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0273375 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0271921 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0271858 |
| TMEM165 | transmembrane protein 165 | -0.0270891 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0267652 |
| JUN | jun proto-oncogene | -0.0266966 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0266697 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0265522 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0264193 |
| S100A6 | S100 calcium binding protein A6 | -0.0262092 |
| SYN3 | synapsin III | -0.0262015 |
| RTN3 | reticulon 3 | -0.0258413 |
| ADIRF | adipogenesis regulatory factor | -0.0258257 |
| SULF2 | sulfatase 2 | -0.0257991 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0255779 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0254893 |
| FBXO11 | F-box protein 11 | -0.0253769 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0253489 |
