| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capmatinib perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capmatinib_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.162423 |
| LMO7 | LIM domain 7 | 0.105647 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.101551 |
| BCL2L1 | BCL2-like 1 | 0.0893792 |
| AHR | aryl hydrocarbon receptor | 0.0796394 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0788828 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0785745 |
| RNF213 | ring finger protein 213 | 0.0757337 |
| SEPTIN9 | septin 9 | 0.0747428 |
| MYOF | myoferlin | 0.069633 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0646058 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0638021 |
| TJP1 | tight junction protein 1 | 0.0619775 |
| KRT18 | keratin 18, type I | 0.0603737 |
| MCU | mitochondrial calcium uniporter | 0.0550096 |
| TMC5 | transmembrane channel-like 5 | 0.0533977 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0527479 |
| LCN2 | lipocalin 2 | 0.0518038 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0517368 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0509517 |
| SP100 | SP100 nuclear antigen | 0.0505475 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0494782 |
| INTS6 | integrator complex subunit 6 | 0.0472157 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0461958 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0461269 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0439039 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0429745 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0428363 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0422593 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0415455 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0409874 |
| CREBBP | CREB binding protein | 0.0399697 |
| CALR | calreticulin | 0.0390724 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0380627 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0376922 |
| FNDC3B | fibronectin type III domain containing 3B | 0.037457 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.037 |
| DSPP | dentin sialophosphoprotein | 0.0367802 |
| POF1B | premature ovarian failure, 1B | 0.0367672 |
| MYO1E | myosin IE | 0.036425 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0364079 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0363468 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0362503 |
| VCL | vinculin | 0.0361878 |
| GPHN | gephyrin | 0.0361798 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0359576 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.035786 |
| ASPH | aspartate beta-hydroxylase | 0.0354509 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0352333 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0348921 |
| RASEF | RAS and EF-hand domain containing | 0.0346385 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0346144 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0333016 |
| ATM | ATM serine/threonine kinase | 0.0331432 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0331234 |
| WWOX | WW domain containing oxidoreductase | 0.0321247 |
| PLSCR1 | phospholipid scramblase 1 | 0.031785 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0317312 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0313156 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0312926 |
| KLF6 | Kruppel-like factor 6 | 0.0311627 |
| EFNB2 | ephrin-B2 | 0.0308115 |
| SMAD3 | SMAD family member 3 | 0.0307893 |
| RPS4X | ribosomal protein S4, X-linked | 0.0303522 |
| RBM47 | RNA binding motif protein 47 | 0.0300417 |
| NFIB | nuclear factor I/B | 0.0295792 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0294531 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0294401 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0291363 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0291092 |
| MACROD2 | MACRO domain containing 2 | 0.0288967 |
| CTBP2 | C-terminal binding protein 2 | 0.0288576 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0284461 |
| STK24 | serine/threonine kinase 24 | 0.0284014 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0281288 |
| LIPH | lipase, member H | 0.0279163 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | 0.0277657 |
| PHF14 | PHD finger protein 14 | 0.0276622 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0271625 |
| SIK3 | SIK family kinase 3 | 0.0271322 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.027088 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0269892 |
| SFTPA2 | surfactant protein A2 | 0.0267691 |
| RIGI | RNA sensor RIG-I | 0.026749 |
| TOB1 | transducer of ERBB2, 1 | 0.0266117 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0264554 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0261189 |
| AEBP2 | AE binding protein 2 | 0.026021 |
| DST | dystonin | 0.0255383 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0253033 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0251669 |
| BPTF | bromodomain PHD finger transcription factor | 0.0251398 |
| XAF1 | XIAP associated factor 1 | 0.0251086 |
| GDA | guanine deaminase | 0.0250608 |
| MX1 | MX dynamin-like GTPase 1 | 0.0247393 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0247008 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0240724 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0240353 |
| CFAP161 | cilia and flagella associated protein 161 | 0.023898 |
| CUX1 | cut-like homeobox 1 | 0.0238715 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.254983 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.114138 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.107768 |
| TMSB10 | thymosin beta 10 | -0.0940981 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0905136 |
| RPS6 | ribosomal protein S6 | -0.085794 |
| POTEF | POTE ankyrin domain family, member F | -0.0835316 |
| WDR45B | WD repeat domain 45B | -0.0737621 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0736501 |
| VEGFA | vascular endothelial growth factor A | -0.0733685 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0719352 |
| RPL35A | ribosomal protein L35a | -0.0701684 |
| NDRG1 | N-myc downstream regulated 1 | -0.0696535 |
| AGR2 | anterior gradient 2 | -0.06943 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0684315 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0657948 |
| GOLGA4 | golgin A4 | -0.0638093 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0625347 |
| HMGA1 | high mobility group AT-hook 1 | -0.062 |
| FTL | ferritin, light polypeptide | -0.0608227 |
| ITGB4 | integrin, beta 4 | -0.0587055 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0581698 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0559464 |
| S100A6 | S100 calcium binding protein A6 | -0.055623 |
| PTMA | prothymosin, alpha | -0.0546884 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0546882 |
| ZNF292 | zinc finger protein 292 | -0.0541316 |
| EMP1 | epithelial membrane protein 1 | -0.0534622 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0528211 |
| PGK1 | phosphoglycerate kinase 1 | -0.0522634 |
| FAM13A | family with sequence similarity 13, member A | -0.0513621 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0497534 |
| ITGA6 | integrin, alpha 6 | -0.0494546 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0490494 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0475516 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0455193 |
| CLDN7 | claudin 7 | -0.0452907 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0443712 |
| H1-0 | H1.0 linker histone | -0.0423544 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0422893 |
| ANLN | anillin, actin binding protein | -0.0418271 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.041105 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0405402 |
| AGR3 | anterior gradient 3 | -0.0400687 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0399646 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0398628 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.037576 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0375753 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0369108 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0364775 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0363521 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0360303 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0357768 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0352141 |
| SETD5 | SET domain containing 5 | -0.0349752 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0348645 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0343075 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0341327 |
| CCNY | cyclin Y | -0.0340513 |
| TPD52 | tumor protein D52 | -0.0335067 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0332462 |
| LYZ | lysozyme | -0.0331423 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0330357 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0329612 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0325079 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0323983 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0322533 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0320234 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0319762 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0319385 |
| RPLP1 | ribosomal protein, large, P1 | -0.0319244 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0315464 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0314473 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0312619 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0310482 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0307944 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0306303 |
| AUTS2 | autism susceptibility candidate 2 | -0.0303395 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0301442 |
| DEK | DEK proto-oncogene | -0.0295887 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0291186 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0290359 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0289536 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0287421 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0285561 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0283833 |
| PERP | PERP, TP53 apoptosis effector | -0.0282973 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0281643 |
| EHBP1 | EH domain binding protein 1 | -0.0280093 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.02771 |
| PTEN | phosphatase and tensin homolog | -0.0276553 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0272543 |
| PFN1 | profilin 1 | -0.0269445 |
| RBM39 | RNA binding motif protein 39 | -0.0266187 |
| ENO1 | enolase 1, (alpha) | -0.0264129 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0263933 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0262314 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.026222 |
| WASF2 | WAS protein family, member 2 | -0.0262121 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0261802 |
