| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capmatinib perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Capmatinib_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RNF213 | ring finger protein 213 | 0.0819785 |
| TXNRD1 | thioredoxin reductase 1 | 0.0780023 |
| ENO1 | enolase 1, (alpha) | 0.0616588 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0581979 |
| LDHA | lactate dehydrogenase A | 0.0555695 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0544105 |
| GRAMD1B | GRAM domain containing 1B | 0.0528007 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.050691 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0476163 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0473877 |
| B2M | beta-2-microglobulin | 0.0473825 |
| RPS3 | ribosomal protein S3 | 0.0472527 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0463268 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0457987 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0445782 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0439194 |
| MYOF | myoferlin | 0.0362432 |
| RPS8 | ribosomal protein S8 | 0.0331589 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0330358 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0307743 |
| RPS4X | ribosomal protein S4, X-linked | 0.030091 |
| RPL37A | ribosomal protein L37a | 0.0298716 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.02958 |
| RPS12 | ribosomal protein S12 | 0.0292366 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.02903 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0290011 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0288302 |
| DST | dystonin | 0.0281299 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0274056 |
| KRT18 | keratin 18, type I | 0.0273148 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0271477 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0265451 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0262366 |
| PRDX1 | peroxiredoxin 1 | 0.0258789 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0254006 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0252358 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0245662 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0245092 |
| RAD51B | RAD51 paralog B | 0.0244899 |
| SP100 | SP100 nuclear antigen | 0.0243543 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0239453 |
| MX1 | MX dynamin-like GTPase 1 | 0.0235726 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0232892 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0229228 |
| PRELID2 | PRELI domain containing 2 | 0.0228256 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0211476 |
| HLA-B | major histocompatibility complex, class I, B | 0.0210832 |
| GOLGB1 | golgin B1 | 0.021034 |
| MKI67 | marker of proliferation Ki-67 | 0.0209102 |
| WWOX | WW domain containing oxidoreductase | 0.0206935 |
| RPS2 | ribosomal protein S2 | 0.0203961 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0203608 |
| CANX | calnexin | 0.0203498 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0201403 |
| RPS29 | ribosomal protein S29 | 0.0199096 |
| ADAR | adenosine deaminase, RNA-specific | 0.0191422 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0189613 |
| CUL4A | cullin 4A | 0.0188861 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0187538 |
| ANGPTL4 | angiopoietin-like 4 | 0.0187486 |
| TPI1 | triosephosphate isomerase 1 | 0.0186616 |
| DNASE1 | deoxyribonuclease I | 0.0184013 |
| RPS17 | ribosomal protein S17 | 0.0182796 |
| PMP22 | peripheral myelin protein 22 | 0.0181647 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.017619 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0175602 |
| RACK1 | receptor for activated C kinase 1 | 0.0172758 |
| CPE | carboxypeptidase E | 0.0170777 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0167735 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.016711 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0165774 |
| BPTF | bromodomain PHD finger transcription factor | 0.0162885 |
| IFI44L | interferon-induced protein 44-like | 0.0154955 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0154951 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0154518 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0153812 |
| ARGLU1 | arginine and glutamate rich 1 | 0.015242 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0151283 |
| SFTPA2 | surfactant protein A2 | 0.0151192 |
| ANKRD12 | ankyrin repeat domain 12 | 0.015068 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0147978 |
| YBX3 | Y box binding protein 3 | 0.0146902 |
| HMOX1 | heme oxygenase 1 | 0.014686 |
| DSPP | dentin sialophosphoprotein | 0.014624 |
| SMYD3 | SET and MYND domain containing 3 | 0.0146079 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0144283 |
| AHR | aryl hydrocarbon receptor | 0.0142976 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0141425 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0141042 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0140481 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0140312 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0138711 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0138652 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0138406 |
| RPS6 | ribosomal protein S6 | 0.0137887 |
| IFI44 | interferon-induced protein 44 | 0.0135856 |
| S100P | S100 calcium binding protein P | 0.0135492 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0135053 |
| FUS | FUS RNA binding protein | 0.0134305 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0134016 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.162226 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.149855 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.116434 |
| TMSB10 | thymosin beta 10 | -0.0990076 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0891457 |
| LAMC2 | laminin, gamma 2 | -0.0831095 |
| ASPH | aspartate beta-hydroxylase | -0.0730618 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0667323 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0666971 |
| EGR1 | early growth response 1 | -0.0640278 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0640034 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0605681 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0592827 |
| H1-0 | H1.0 linker histone | -0.058991 |
| WASF2 | WAS protein family, member 2 | -0.0550238 |
| TMEM165 | transmembrane protein 165 | -0.0544912 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0543446 |
| LMO7 | LIM domain 7 | -0.0521587 |
| FAM13A | family with sequence similarity 13, member A | -0.0515103 |
| SPAG9 | sperm associated antigen 9 | -0.0505117 |
| SCEL | sciellin | -0.0502569 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.050195 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0499729 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0497604 |
| UVRAG | UV radiation resistance associated | -0.048668 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0474991 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0474414 |
| ACTG1 | actin gamma 1 | -0.0461021 |
| ANXA2 | annexin A2 | -0.0455767 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0453801 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0448793 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0443696 |
| PDE8A | phosphodiesterase 8A | -0.0429272 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.04275 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0419699 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0415001 |
| NABP1 | nucleic acid binding protein 1 | -0.0412733 |
| PTMA | prothymosin, alpha | -0.0401342 |
| LAMA4 | laminin, alpha 4 | -0.039515 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.038816 |
| PKM | pyruvate kinase, muscle | -0.0384484 |
| NDRG1 | N-myc downstream regulated 1 | -0.0382102 |
| INTS6 | integrator complex subunit 6 | -0.0379002 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0375391 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0372472 |
| MCL1 | myeloid cell leukemia 1 | -0.0370282 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0367687 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0358894 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0354048 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0345061 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0341408 |
| HMGA1 | high mobility group AT-hook 1 | -0.0327485 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.032617 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0325557 |
| ATG7 | autophagy related 7 | -0.0320611 |
| RCOR1 | REST corepressor 1 | -0.0319089 |
| TPD52 | tumor protein D52 | -0.0319083 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0316124 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0305365 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0303094 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0302493 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0299925 |
| STC1 | stanniocalcin 1 | -0.0294314 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0294011 |
| NPTN | neuroplastin | -0.0291397 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0290467 |
| POTEF | POTE ankyrin domain family, member F | -0.0290387 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0289556 |
| RUNX1 | runt-related transcription factor 1 | -0.0288997 |
| LAMB3 | laminin, beta 3 | -0.0288468 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0284332 |
| RNF145 | ring finger protein 145 | -0.0284229 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0283648 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0283536 |
| HELZ | helicase with zinc finger | -0.0280852 |
| CCNL1 | cyclin L1 | -0.0280039 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0278134 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0271949 |
| OGA | O-GlcNAcase | -0.0270627 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0270428 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0260179 |
| USP3 | ubiquitin specific peptidase 3 | -0.0255633 |
| FBXO11 | F-box protein 11 | -0.0255345 |
| SETD5 | SET domain containing 5 | -0.025245 |
| EFNA5 | ephrin-A5 | -0.0244927 |
| SLMAP | sarcolemma associated protein | -0.0244643 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0242105 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0240626 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0238399 |
| ATP13A3 | ATPase type 13A3 | -0.0235392 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0235219 |
| MED13L | mediator complex subunit 13-like | -0.023281 |
| AHNAK | AHNAK nucleoprotein | -0.0231078 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0228301 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0228146 |
| SBF2 | SET binding factor 2 | -0.0226073 |
| PRKCA | protein kinase C, alpha | -0.0224641 |
| SRP54 | signal recognition particle 54kDa | -0.0223645 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0218681 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0218276 |
