| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capmatinib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capmatinib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI44L | interferon-induced protein 44-like | 0.0820962 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0734897 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0629525 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.056745 |
| ANGPTL4 | angiopoietin-like 4 | 0.0554228 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0521915 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0480464 |
| LDHA | lactate dehydrogenase A | 0.0449992 |
| INTS6 | integrator complex subunit 6 | 0.0421559 |
| NDRG1 | N-myc downstream regulated 1 | 0.0407712 |
| CA12 | carbonic anhydrase XII | 0.0369819 |
| NAV2 | neuron navigator 2 | 0.0362256 |
| EXT1 | exostosin glycosyltransferase 1 | 0.036089 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0360347 |
| B2M | beta-2-microglobulin | 0.0351061 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0341717 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0341086 |
| SP100 | SP100 nuclear antigen | 0.0327555 |
| MX1 | MX dynamin-like GTPase 1 | 0.0324669 |
| RNF213 | ring finger protein 213 | 0.0305416 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0304852 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0303876 |
| RPS12 | ribosomal protein S12 | 0.0291887 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.028773 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0287532 |
| PRELID2 | PRELI domain containing 2 | 0.0284941 |
| APP | amyloid beta (A4) precursor protein | 0.0283428 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0283077 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0282529 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0280087 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0272336 |
| RPL37 | ribosomal protein L37 | 0.0267157 |
| SQSTM1 | sequestosome 1 | 0.0259719 |
| PCDH7 | protocadherin 7 | 0.0259603 |
| MX2 | MX dynamin-like GTPase 2 | 0.0258915 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0253275 |
| RACK1 | receptor for activated C kinase 1 | 0.0248617 |
| WWOX | WW domain containing oxidoreductase | 0.0244232 |
| RPS4X | ribosomal protein S4, X-linked | 0.024053 |
| RPS8 | ribosomal protein S8 | 0.02322 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0231861 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0223604 |
| ENO1 | enolase 1, (alpha) | 0.0222031 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0218511 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0209919 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0209537 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0208403 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0204534 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0204313 |
| SFTPA2 | surfactant protein A2 | 0.0203857 |
| RPS17 | ribosomal protein S17 | 0.0203549 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0202828 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0202614 |
| TRIM25 | tripartite motif containing 25 | 0.0202301 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0201367 |
| RPL23 | ribosomal protein L23 | 0.0194162 |
| RPL31 | ribosomal protein L31 | 0.0191973 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0188178 |
| IRF1 | interferon regulatory factor 1 | 0.0185501 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0184477 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.018359 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0182982 |
| MXI1 | MAX interactor 1, dimerization protein | 0.018252 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0181793 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0181499 |
| RPS3 | ribosomal protein S3 | 0.0181246 |
| LOXL2 | lysyl oxidase-like 2 | 0.0180765 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0179151 |
| IFI44 | interferon-induced protein 44 | 0.0178849 |
| AUTS2 | autism susceptibility candidate 2 | 0.0177752 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0177496 |
| NEBL | nebulette | 0.0177411 |
| ASPH | aspartate beta-hydroxylase | 0.0175722 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0168838 |
| NEGR1 | neuronal growth regulator 1 | 0.0168825 |
| DST | dystonin | 0.0167801 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0166934 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0166769 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | 0.0165787 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0164369 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0162686 |
| ADAR | adenosine deaminase, RNA-specific | 0.0161956 |
| SLFN5 | schlafen family member 5 | 0.0161484 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.016068 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0160402 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.015981 |
| GPHN | gephyrin | 0.0158033 |
| HLA-E | major histocompatibility complex, class I, E | 0.0157854 |
| GPR176 | G protein-coupled receptor 176 | 0.0156636 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0155608 |
| ARFGEF3 | ARFGEF family member 3 | 0.0155468 |
| PALLD | palladin, cytoskeletal associated protein | 0.0154656 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0152253 |
| ZNF638 | zinc finger protein 638 | 0.0151793 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0151353 |
| RPL5 | ribosomal protein L5 | 0.0151271 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0151131 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0149771 |
| RPL37A | ribosomal protein L37a | 0.014858 |
| SEPTIN9 | septin 9 | 0.0148392 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.17582 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.139362 |
| CD44 | CD44 molecule (Indian blood group) | -0.135123 |
| FNDC3B | fibronectin type III domain containing 3B | -0.111645 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.109563 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.100046 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.099673 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0984826 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0977301 |
| OSMR | oncostatin M receptor | -0.095253 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0939929 |
| RBM39 | RNA binding motif protein 39 | -0.0925078 |
| HMGA2 | high mobility group AT-hook 2 | -0.089336 |
| GOLGA4 | golgin A4 | -0.083688 |
| CDH13 | cadherin 13 | -0.0818679 |
| EFNA5 | ephrin-A5 | -0.0761632 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0759307 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0758839 |
| STC1 | stanniocalcin 1 | -0.0755742 |
| TMSB10 | thymosin beta 10 | -0.0711489 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0670873 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0640429 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0636178 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0628311 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0620909 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0600021 |
| VMP1 | vacuole membrane protein 1 | -0.0574174 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0572159 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0570123 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0555689 |
| SETD5 | SET domain containing 5 | -0.0551353 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0546212 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0541801 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0534641 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0532384 |
| LOX | lysyl oxidase | -0.0530312 |
| ATP13A3 | ATPase type 13A3 | -0.0524594 |
| JMJD1C | jumonji domain containing 1C | -0.0493195 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0489423 |
| EGR1 | early growth response 1 | -0.048406 |
| USP34 | ubiquitin specific peptidase 34 | -0.0474688 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0464491 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0451203 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0441249 |
| ANXA2 | annexin A2 | -0.0435415 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0430966 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0428209 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0427738 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0423064 |
| ETV6 | ets variant 6 | -0.0419396 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0418318 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0411602 |
| DNER | delta/notch-like EGF repeat containing | -0.040864 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0406233 |
| SPAG9 | sperm associated antigen 9 | -0.0404932 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0399155 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0398582 |
| OGA | O-GlcNAcase | -0.039555 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0395009 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0390721 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0388822 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0388476 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0386874 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0382989 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0378953 |
| SRP54 | signal recognition particle 54kDa | -0.037495 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0374158 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0370019 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.036797 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0367778 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0364604 |
| SBF2 | SET binding factor 2 | -0.0364258 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0363596 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0362941 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0360654 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.036062 |
| COPA | coatomer protein complex, subunit alpha | -0.0356757 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0350062 |
| PARD3 | par-3 family cell polarity regulator | -0.0349076 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0346302 |
| RAB1A | RAB1A, member RAS oncogene family | -0.034288 |
| CLMP | CXADR-like membrane protein | -0.0342296 |
| PCNX1 | pecanex 1 | -0.0340944 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0340301 |
| CD109 | CD109 molecule | -0.0339874 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0338603 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0335976 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | -0.0334283 |
| MTSS1 | metastasis suppressor 1 | -0.0334087 |
| EXOC4 | exocyst complex component 4 | -0.0330693 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0330063 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0330006 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0329693 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0328927 |
| VRK2 | vaccinia related kinase 2 | -0.0328779 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0326294 |
| LUZP1 | leucine zipper protein 1 | -0.0324435 |
| CDCP1 | CUB domain containing protein 1 | -0.0324093 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0323387 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.031932 |
