| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capmatinib perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capmatinib_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.10804 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0904651 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0833992 |
| PDE10A | phosphodiesterase 10A | 0.0813175 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0758325 |
| AEBP2 | AE binding protein 2 | 0.0632352 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0593839 |
| HLA-B | major histocompatibility complex, class I, B | 0.0582794 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0575542 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0546845 |
| RNF213 | ring finger protein 213 | 0.053915 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0537932 |
| WWOX | WW domain containing oxidoreductase | 0.0513408 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0456184 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0449701 |
| INTS6 | integrator complex subunit 6 | 0.0416053 |
| ATXN1 | ataxin 1 | 0.0411749 |
| FNDC3B | fibronectin type III domain containing 3B | 0.040596 |
| RPS4X | ribosomal protein S4, X-linked | 0.0405322 |
| GOLGB1 | golgin B1 | 0.0401341 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0389018 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0378338 |
| DENND5B | DENN/MADD domain containing 5B | 0.0378098 |
| BMP5 | bone morphogenetic protein 5 | 0.0360878 |
| PRELID2 | PRELI domain containing 2 | 0.0360058 |
| RPS3 | ribosomal protein S3 | 0.0346439 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0345575 |
| VCL | vinculin | 0.0338063 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0332308 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0331435 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0329201 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.032829 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0327559 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0324325 |
| DST | dystonin | 0.0317086 |
| ATF6 | activating transcription factor 6 | 0.0312857 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0296249 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0294885 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0288371 |
| MACROD2 | MACRO domain containing 2 | 0.0286058 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.028112 |
| RPL37A | ribosomal protein L37a | 0.0280933 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0276775 |
| BPTF | bromodomain PHD finger transcription factor | 0.0276296 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0276036 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0271996 |
| RSU1 | Ras suppressor protein 1 | 0.0271147 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0268312 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0266607 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.026134 |
| RPS12 | ribosomal protein S12 | 0.025247 |
| SMYD3 | SET and MYND domain containing 3 | 0.0247044 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.024014 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0237217 |
| DSPP | dentin sialophosphoprotein | 0.0235491 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0235209 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0234731 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0233795 |
| SIK3 | SIK family kinase 3 | 0.022806 |
| PCNX4 | pecanex 4 | 0.0225999 |
| SFTPA2 | surfactant protein A2 | 0.0224891 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0224852 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0224537 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0223616 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0221194 |
| SSH2 | slingshot protein phosphatase 2 | 0.0211109 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0210971 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0209428 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0207343 |
| KIF1A | kinesin family member 1A | 0.0205754 |
| NEBL | nebulette | 0.0202609 |
| CALR | calreticulin | 0.0202368 |
| PCDH7 | protocadherin 7 | 0.0200461 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0199061 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0197061 |
| EFNA1 | ephrin-A1 | 0.0195945 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0194975 |
| MRTFA | myocardin related transcription factor A | 0.0193151 |
| ADA | adenosine deaminase | 0.019287 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0192471 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0191413 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0190833 |
| NRDC | nardilysin convertase | 0.0190298 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0189803 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0187273 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0187074 |
| PRKCE | protein kinase C, epsilon | 0.0185476 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0184249 |
| B2M | beta-2-microglobulin | 0.0184128 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0183036 |
| RPS8 | ribosomal protein S8 | 0.0182714 |
| SVIL | supervillin | 0.0182697 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0181468 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0181447 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0179041 |
| ETV6 | ets variant 6 | 0.017862 |
| MORF4L2 | mortality factor 4 like 2 | 0.0177567 |
| LOXL2 | lysyl oxidase-like 2 | 0.0175874 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0175628 |
| HDAC4 | histone deacetylase 4 | 0.0175521 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.223288 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.161307 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.128061 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.123871 |
| EGR1 | early growth response 1 | -0.0985842 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0917858 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0835841 |
| TXNRD1 | thioredoxin reductase 1 | -0.0818517 |
| RTN4 | reticulon 4 | -0.0757411 |
| PFN1 | profilin 1 | -0.0726065 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0661411 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0655594 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.065052 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0645219 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0636242 |
| PHIP | pleckstrin homology domain interacting protein | -0.0605507 |
| POTEF | POTE ankyrin domain family, member F | -0.059172 |
| TMSB10 | thymosin beta 10 | -0.0585717 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0584532 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0568858 |
| VIM | vimentin | -0.0533769 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0529198 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0525671 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0522607 |
| CCNL1 | cyclin L1 | -0.0497413 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0491401 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.047265 |
| RPLP0 | ribosomal protein, large, P0 | -0.0446743 |
| YBX3 | Y box binding protein 3 | -0.0443519 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0439599 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.043659 |
| PTMA | prothymosin, alpha | -0.0436295 |
| CDK17 | cyclin-dependent kinase 17 | -0.0419864 |
| HMGA1 | high mobility group AT-hook 1 | -0.0419124 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0416211 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0406647 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0404737 |
| LDHB | lactate dehydrogenase B | -0.0376826 |
| MMP12 | matrix metallopeptidase 12 | -0.0376755 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0375978 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0368096 |
| RRM2 | ribonucleotide reductase M2 | -0.0368061 |
| RUSC2 | RUN and SH3 domain containing 2 | -0.0365542 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0360243 |
| STC1 | stanniocalcin 1 | -0.0359629 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0357826 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0353342 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0351911 |
| TPI1 | triosephosphate isomerase 1 | -0.0350839 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0350449 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0342843 |
| SEPTIN7 | septin 7 | -0.0327624 |
| PCNX1 | pecanex 1 | -0.0324574 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.032084 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0320827 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0315892 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0315879 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.031546 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0313363 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0313306 |
| PCBP2 | poly(rC) binding protein 2 | -0.031244 |
| H1-0 | H1.0 linker histone | -0.0311323 |
| NABP1 | nucleic acid binding protein 1 | -0.0311276 |
| DIAPH3 | diaphanous-related formin 3 | -0.0309701 |
| RBM25 | RNA binding motif protein 25 | -0.0306945 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0306756 |
| TUBA1B | tubulin, alpha 1b | -0.030665 |
| XPO1 | exportin 1 | -0.0305775 |
| CDCP1 | CUB domain containing protein 1 | -0.030332 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0302716 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0302221 |
| BBX | bobby sox homolog (Drosophila) | -0.0302094 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.030018 |
| FMNL2 | formin-like 2 | -0.0298694 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.029235 |
| MCL1 | myeloid cell leukemia 1 | -0.0291549 |
| PGK1 | phosphoglycerate kinase 1 | -0.0289454 |
| WASF2 | WAS protein family, member 2 | -0.0289198 |
| SBF2 | SET binding factor 2 | -0.0287996 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0284295 |
| YBX1 | Y box binding protein 1 | -0.0283978 |
| MT2A | metallothionein 2A | -0.0283896 |
| RPS21 | ribosomal protein S21 | -0.0282406 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0281209 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0276437 |
| OGA | O-GlcNAcase | -0.0273851 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0272515 |
| SRPK2 | SRSF protein kinase 2 | -0.0271566 |
| SNX9 | sorting nexin 9 | -0.0271413 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0271335 |
| ACTG1 | actin gamma 1 | -0.0268728 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0268047 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0267735 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0265353 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0264627 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0263466 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0263168 |
| RASA2 | RAS p21 protein activator 2 | -0.0262644 |
| CENPF | centromere protein F, 350/400kDa | -0.026204 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.0260719 |
