| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capmatinib perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capmatinib_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.113793 |
| NDRG1 | N-myc downstream regulated 1 | 0.0952927 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0543566 |
| FHIT | fragile histidine triad | 0.0507711 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.0446086 |
| TUFT1 | tuftelin 1 | 0.0422296 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0407186 |
| ARRDC3 | arrestin domain containing 3 | 0.0384157 |
| RPS12 | ribosomal protein S12 | 0.0362751 |
| RNF213 | ring finger protein 213 | 0.0352475 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0345437 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0334356 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0314039 |
| PCBP2 | poly(rC) binding protein 2 | 0.0309493 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.030859 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0306418 |
| EXT1 | exostosin glycosyltransferase 1 | 0.030258 |
| RYBP | RING1 and YY1 binding protein | 0.0293852 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0292625 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0287012 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0285224 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0271034 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0269901 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0268046 |
| MX1 | MX dynamin-like GTPase 1 | 0.0251219 |
| SEPTIN11 | septin 11 | 0.0250274 |
| RACK1 | receptor for activated C kinase 1 | 0.0246495 |
| RAD51B | RAD51 paralog B | 0.0244978 |
| RPL9 | ribosomal protein L9 | 0.0242887 |
| RPS17 | ribosomal protein S17 | 0.0242456 |
| STEAP4 | STEAP family member 4 | 0.0242286 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0234566 |
| GPHN | gephyrin | 0.0233789 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0231646 |
| CCNL1 | cyclin L1 | 0.0230437 |
| PCM1 | pericentriolar material 1 | 0.0222127 |
| SMYD3 | SET and MYND domain containing 3 | 0.0221575 |
| KIAA1217 | KIAA1217 | 0.0218602 |
| RPS2 | ribosomal protein S2 | 0.021397 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0213654 |
| RPS3 | ribosomal protein S3 | 0.0206607 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0206537 |
| XPO1 | exportin 1 | 0.0206413 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0203775 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0203566 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0202749 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0198405 |
| SEPTIN9 | septin 9 | 0.0196754 |
| RPL5 | ribosomal protein L5 | 0.0191572 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0190905 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0189779 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0189266 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0187997 |
| RPL37A | ribosomal protein L37a | 0.0187748 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0187026 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0186047 |
| PALLD | palladin, cytoskeletal associated protein | 0.0185189 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0184947 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | 0.0183861 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0179972 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0176788 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0173182 |
| MSN | moesin | 0.0172833 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0172249 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0171653 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0170573 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0168854 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0168218 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0167961 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0165636 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0165078 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0164827 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0163913 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0163576 |
| INTS6 | integrator complex subunit 6 | 0.0162608 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0162388 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.01596 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0159493 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.015652 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0155224 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0152743 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.015246 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.015184 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0151094 |
| SGMS2 | sphingomyelin synthase 2 | 0.0149633 |
| IFI44L | interferon-induced protein 44-like | 0.0149537 |
| BRD2 | bromodomain containing 2 | 0.014804 |
| OCLN | occludin | 0.0147239 |
| EFNA1 | ephrin-A1 | 0.0147045 |
| NPTN | neuroplastin | 0.0146943 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0146675 |
| FUS | FUS RNA binding protein | 0.0146115 |
| WWC1 | WW and C2 domain containing 1 | 0.0145506 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0144973 |
| MKI67 | marker of proliferation Ki-67 | 0.0144933 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0144176 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0143537 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0143326 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.014192 |
| LGMN | legumain | 0.0141874 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.181516 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.149893 |
| LMO7 | LIM domain 7 | -0.147042 |
| ASPH | aspartate beta-hydroxylase | -0.145204 |
| ACTG1 | actin gamma 1 | -0.125666 |
| LAMB3 | laminin, beta 3 | -0.104521 |
| TMSB10 | thymosin beta 10 | -0.102028 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.097334 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0966523 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0889856 |
| PTMA | prothymosin, alpha | -0.0873945 |
| TOP1 | topoisomerase (DNA) I | -0.0867655 |
| TMSB4X | thymosin beta 4, X-linked | -0.0862524 |
| LAMC2 | laminin, gamma 2 | -0.083872 |
| PGK1 | phosphoglycerate kinase 1 | -0.0834178 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.081663 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.079353 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0782103 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0780643 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0766606 |
| CD2AP | CD2-associated protein | -0.0718571 |
| FN1 | fibronectin 1 | -0.0716748 |
| POTEF | POTE ankyrin domain family, member F | -0.069716 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.069423 |
| CCND1 | cyclin D1 | -0.0682653 |
| UBC | ubiquitin C | -0.0645911 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0641963 |
| S100A6 | S100 calcium binding protein A6 | -0.0635309 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0628689 |
| ANXA2 | annexin A2 | -0.0609644 |
| FAM3C | family with sequence similarity 3, member C | -0.0597036 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.059618 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0595488 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0560914 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0557533 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.055628 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0546301 |
| FTL | ferritin, light polypeptide | -0.0524663 |
| RAD21 | RAD21 homolog (S. pombe) | -0.052196 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0511411 |
| TPM4 | tropomyosin 4 | -0.0509433 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0507683 |
| EFNA5 | ephrin-A5 | -0.0481974 |
| TMEM263 | transmembrane protein 263 | -0.0472359 |
| ERBIN | erbb2 interacting protein | -0.0465925 |
| MYO6 | myosin VI | -0.0463665 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0454318 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0452584 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0451371 |
| CDCP1 | CUB domain containing protein 1 | -0.0450787 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0444853 |
| EPCAM | epithelial cell adhesion molecule | -0.0443398 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0442307 |
| S100A10 | S100 calcium binding protein A10 | -0.043482 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.04304 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0423295 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0421665 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.042158 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0421467 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0417673 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0404976 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0402822 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0402195 |
| CSTB | cystatin B (stefin B) | -0.0401009 |
| SLMAP | sarcolemma associated protein | -0.0400494 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0398533 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0391109 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0381995 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0381691 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0380306 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0377938 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0372927 |
| RASAL2 | RAS protein activator like 2 | -0.0372625 |
| PLAU | plasminogen activator, urokinase | -0.0368432 |
| JMJD1C | jumonji domain containing 1C | -0.0368216 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0364594 |
| DSG2 | desmoglein 2 | -0.0363824 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0363031 |
| ARF1 | ADP-ribosylation factor 1 | -0.0361164 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0359493 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0357908 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.03531 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0352585 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.035074 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0347096 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0345579 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0344307 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0343958 |
| KRT7 | keratin 7, type II | -0.0342558 |
| MXD1 | MAX dimerization protein 1 | -0.0336255 |
| FAM107B | family with sequence similarity 107, member B | -0.0333436 |
| GNAS | GNAS complex locus | -0.0332478 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0325859 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0321339 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0315438 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.031511 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0315099 |
| HMGB2 | high mobility group box 2 | -0.0313269 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0313236 |
| HDLBP | high density lipoprotein binding protein | -0.0312363 |
