| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capmatinib perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capmatinib_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| WSB1 | WD repeat and SOCS box containing 1 | 0.10999 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0968404 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0903826 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0804898 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0798078 |
| CALR | calreticulin | 0.0720404 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0689751 |
| APP | amyloid beta (A4) precursor protein | 0.0682822 |
| MED13L | mediator complex subunit 13-like | 0.0609104 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0603956 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.059253 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.059051 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0582227 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0575389 |
| FOXP2 | forkhead box P2 | 0.0572454 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0566461 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.055151 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.052604 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0520352 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0503114 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0500579 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.049508 |
| RCOR1 | REST corepressor 1 | 0.0493477 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0489691 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0481685 |
| B2M | beta-2-microglobulin | 0.0474405 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0460158 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0458108 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0450198 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.044597 |
| COL3A1 | collagen, type III, alpha 1 | 0.0433785 |
| RPL37 | ribosomal protein L37 | 0.0431884 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0425248 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0421629 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0413529 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0410713 |
| ATXN2 | ataxin 2 | 0.0399941 |
| RPL31 | ribosomal protein L31 | 0.0398717 |
| CDC14A | cell division cycle 14A | 0.0397282 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0394173 |
| GPHN | gephyrin | 0.039402 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.039384 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0393238 |
| RPS8 | ribosomal protein S8 | 0.0389488 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0374921 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0374736 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0372154 |
| PHIP | pleckstrin homology domain interacting protein | 0.0365169 |
| SQSTM1 | sequestosome 1 | 0.0363882 |
| DENND4A | DENN/MADD domain containing 4A | 0.0363684 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0360751 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.035748 |
| GOLGA4 | golgin A4 | 0.0356802 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0356273 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0353824 |
| RPS12 | ribosomal protein S12 | 0.0351006 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0349329 |
| RPL37A | ribosomal protein L37a | 0.0348127 |
| MORF4L2 | mortality factor 4 like 2 | 0.0341924 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0340227 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0339123 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.0338222 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0336195 |
| ARRDC3 | arrestin domain containing 3 | 0.033451 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0333895 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0332971 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0332111 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.032992 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0322291 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0322039 |
| RPL9 | ribosomal protein L9 | 0.0321812 |
| FBXO11 | F-box protein 11 | 0.0321256 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.032114 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0320006 |
| RPS3 | ribosomal protein S3 | 0.0316351 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0314557 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.031442 |
| RBM20 | RNA binding motif protein 20 | 0.0313001 |
| ITSN2 | intersectin 2 | 0.0311994 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.030921 |
| NCOA1 | nuclear receptor coactivator 1 | 0.0305696 |
| SRPK2 | SRSF protein kinase 2 | 0.0304858 |
| RREB1 | ras responsive element binding protein 1 | 0.0303773 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0303246 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0302421 |
| SPAG9 | sperm associated antigen 9 | 0.0301842 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.030174 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0299573 |
| INTS6 | integrator complex subunit 6 | 0.0299197 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0298037 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0295088 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0294815 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0293138 |
| LIN28B | lin-28 homolog B (C. elegans) | 0.0292485 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.029092 |
| XPO1 | exportin 1 | 0.0290226 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0289863 |
| OPHN1 | oligophrenin 1 | 0.0289099 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0288014 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0287267 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.150214 |
| ITGAV | integrin, alpha V | -0.146423 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.097685 |
| CADM2 | cell adhesion molecule 2 | -0.0957199 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0873014 |
| POTEF | POTE ankyrin domain family, member F | -0.080637 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0788512 |
| PFN1 | profilin 1 | -0.0785267 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0780877 |
| TMSB10 | thymosin beta 10 | -0.0761437 |
| FNDC3B | fibronectin type III domain containing 3B | -0.071266 |
| GPC3 | glypican 3 | -0.0697601 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0650068 |
| THBS1 | thrombospondin 1 | -0.062044 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0618824 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0599126 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0587928 |
| MKI67 | marker of proliferation Ki-67 | -0.0566288 |
| TMSB4X | thymosin beta 4, X-linked | -0.0565219 |
| DST | dystonin | -0.0557426 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0546651 |
| CENPF | centromere protein F, 350/400kDa | -0.0534168 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0523007 |
| H1-0 | H1.0 linker histone | -0.0517463 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0493253 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0487503 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0485427 |
| CBX3 | chromobox homolog 3 | -0.0415224 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0414207 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0402777 |
| EXOC4 | exocyst complex component 4 | -0.040157 |
| AHNAK | AHNAK nucleoprotein | -0.0399158 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0382992 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.038289 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.037527 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0374748 |
| PEG10 | paternally expressed 10 | -0.0374033 |
| NTM | neurotrimin | -0.037268 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0372168 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0364799 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0362034 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.03604 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0354855 |
| HMGA1 | high mobility group AT-hook 1 | -0.0352543 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0342611 |
| RAI1 | retinoic acid induced 1 | -0.034083 |
| RAD51B | RAD51 paralog B | -0.0340262 |
| CCN2 | cellular communication network factor 2 | -0.0336504 |
| DEK | DEK proto-oncogene | -0.033391 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0324455 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0324095 |
| PTMA | prothymosin, alpha | -0.0315721 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0313804 |
| TEX11 | testis expressed 11 | -0.0313258 |
| HMGB1 | high mobility group box 1 | -0.031182 |
| ANXA5 | annexin A5 | -0.0301709 |
| LDHB | lactate dehydrogenase B | -0.0301352 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0299706 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.029924 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0299086 |
| SHROOM3 | shroom family member 3 | -0.0298187 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0296463 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0291418 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0290052 |
| ACTG1 | actin gamma 1 | -0.0289752 |
| TPM3 | tropomyosin 3 | -0.0286658 |
| BSG | basigin (Ok blood group) | -0.0286508 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0286385 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.0286325 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0285715 |
| NPAS3 | neuronal PAS domain protein 3 | -0.028564 |
| UBXN4 | UBX domain protein 4 | -0.0284718 |
| PDGFC | platelet derived growth factor C | -0.0280163 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0275215 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.027416 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0274079 |
| YBX1 | Y box binding protein 1 | -0.027281 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0268818 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.0265407 |
| CAVIN1 | caveolae associated protein 1 | -0.0265273 |
| RTN4 | reticulon 4 | -0.0265137 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0264641 |
| PCBP2 | poly(rC) binding protein 2 | -0.0262522 |
| HMGA2 | high mobility group AT-hook 2 | -0.0258832 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0257586 |
| UPP1 | uridine phosphorylase 1 | -0.025754 |
| TUBA1B | tubulin, alpha 1b | -0.0249344 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0249117 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0249004 |
| EMP1 | epithelial membrane protein 1 | -0.0248377 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | -0.0248186 |
| WDR43 | WD repeat domain 43 | -0.0247759 |
| ZNF608 | zinc finger protein 608 | -0.024768 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0246689 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0246247 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0246002 |
| MAGT1 | magnesium transporter 1 | -0.0245714 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.024457 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0242133 |
| TPM4 | tropomyosin 4 | -0.0240759 |
