| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capmatinib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capmatinib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.0830638 |
| RPS4X | ribosomal protein S4, X-linked | 0.077355 |
| RPS12 | ribosomal protein S12 | 0.0562621 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0500476 |
| HLA-B | major histocompatibility complex, class I, B | 0.0423082 |
| RPS3 | ribosomal protein S3 | 0.0388279 |
| ARRDC3 | arrestin domain containing 3 | 0.0384312 |
| RPS2 | ribosomal protein S2 | 0.031793 |
| RPL37A | ribosomal protein L37a | 0.0316123 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0314495 |
| MORF4L2 | mortality factor 4 like 2 | 0.030924 |
| RPS8 | ribosomal protein S8 | 0.0305963 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0303899 |
| RPL23 | ribosomal protein L23 | 0.0289044 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0284812 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.026294 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0261133 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0260371 |
| RACK1 | receptor for activated C kinase 1 | 0.0257181 |
| RPL12 | ribosomal protein L12 | 0.0254133 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0237895 |
| KLF6 | Kruppel-like factor 6 | 0.0237774 |
| RPL26 | ribosomal protein L26 | 0.0237652 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0234192 |
| SFTPA2 | surfactant protein A2 | 0.0232476 |
| B2M | beta-2-microglobulin | 0.0232476 |
| RPL36 | ribosomal protein L36 | 0.0228321 |
| EZR | ezrin | 0.0220814 |
| LDHA | lactate dehydrogenase A | 0.0218773 |
| HSPA8 | heat shock 70kDa protein 8 | 0.021751 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0205078 |
| YBX1 | Y box binding protein 1 | 0.0195426 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0194481 |
| RPL5 | ribosomal protein L5 | 0.0189598 |
| RPS17 | ribosomal protein S17 | 0.0188925 |
| RPS19 | ribosomal protein S19 | 0.0187336 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0185127 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.017112 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.01688 |
| SERINC1 | serine incorporator 1 | 0.0167462 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0167425 |
| NONO | non-POU domain containing, octamer-binding | 0.0166814 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0165679 |
| RPS23 | ribosomal protein S23 | 0.0162815 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.016107 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.0158045 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0157627 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0155922 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0155006 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0154287 |
| SPAG9 | sperm associated antigen 9 | 0.0152939 |
| ANXA1 | annexin A1 | 0.0152887 |
| RPL11 | ribosomal protein L11 | 0.0150275 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0149568 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0148544 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0147587 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0146747 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0145985 |
| SQSTM1 | sequestosome 1 | 0.0145934 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0142145 |
| NDRG1 | N-myc downstream regulated 1 | 0.0141592 |
| RPS29 | ribosomal protein S29 | 0.0140256 |
| RPS6 | ribosomal protein S6 | 0.0140027 |
| SET | SET nuclear proto-oncogene | 0.0139501 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.01376 |
| APP | amyloid beta (A4) precursor protein | 0.0136449 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0135526 |
| RPL31 | ribosomal protein L31 | 0.0135281 |
| FLNA | filamin A, alpha | 0.0133117 |
| RPL9 | ribosomal protein L9 | 0.0130742 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0128452 |
| FTL | ferritin, light polypeptide | 0.0128235 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.012752 |
| MKI67 | marker of proliferation Ki-67 | 0.0127089 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.012249 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0121849 |
| RPL38 | ribosomal protein L38 | 0.0121316 |
| RPL14 | ribosomal protein L14 | 0.0121113 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0120254 |
| RPL7 | ribosomal protein L7 | 0.0119295 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0117137 |
| DUSP10 | dual specificity phosphatase 10 | 0.0116391 |
| RPL18 | ribosomal protein L18 | 0.0116381 |
| RPL35 | ribosomal protein L35 | 0.0116188 |
| JMJD1C | jumonji domain containing 1C | 0.0115606 |
| SDC4 | syndecan 4 | 0.0112758 |
| RPL36A | ribosomal protein L36a | 0.0112584 |
| PAPOLA | poly(A) polymerase alpha | 0.0111613 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0111609 |
| RPS27 | ribosomal protein S27 | 0.0111557 |
| SYAP1 | synapse associated protein 1 | 0.0109448 |
| BCL2L1 | BCL2-like 1 | 0.0109058 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0107147 |
| ENO1 | enolase 1, (alpha) | 0.0106459 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0105721 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0105349 |
| ATF3 | activating transcription factor 3 | 0.0105224 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0104876 |
| RPL37 | ribosomal protein L37 | 0.0104282 |
| TMF1 | TATA element modulatory factor 1 | 0.0101283 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | -0.229999 |
| FN1 | fibronectin 1 | -0.224536 |
| FRMD4A | FERM domain containing 4A | -0.209272 |
| VIM | vimentin | -0.155086 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.147147 |
| GLIS3 | GLIS family zinc finger 3 | -0.132187 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.111378 |
| PDE10A | phosphodiesterase 10A | -0.10855 |
| CADM1 | cell adhesion molecule 1 | -0.102069 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0966509 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0939443 |
| RAI14 | retinoic acid induced 14 | -0.0916524 |
| HMGA2 | high mobility group AT-hook 2 | -0.0906019 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0843662 |
| CDH13 | cadherin 13 | -0.0810124 |
| DST | dystonin | -0.0808208 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0802465 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0798985 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0793623 |
| DIAPH2 | diaphanous-related formin 2 | -0.0787479 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0778338 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0741744 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0686672 |
| VCAN | versican | -0.0685753 |
| CD44 | CD44 molecule (Indian blood group) | -0.0680152 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0678973 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0664555 |
| TNS3 | tensin 3 | -0.0648267 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0641905 |
| PLIN2 | perilipin 2 | -0.0630608 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0627304 |
| PGK1 | phosphoglycerate kinase 1 | -0.0625505 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0620274 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0619421 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0615086 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0603225 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0598496 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0583031 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0558432 |
| NAV1 | neuron navigator 1 | -0.0546188 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0516567 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0492605 |
| CTSD | cathepsin D | -0.0491799 |
| EGR1 | early growth response 1 | -0.048648 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0480413 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0470644 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0469131 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0454311 |
| VCL | vinculin | -0.0451061 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0450673 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0438982 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0431993 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0431483 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0427275 |
| MMP12 | matrix metallopeptidase 12 | -0.0426825 |
| ATXN1 | ataxin 1 | -0.0424701 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0422566 |
| AHNAK | AHNAK nucleoprotein | -0.0422388 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.042219 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0421231 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0418901 |
| EGFR | epidermal growth factor receptor | -0.0417567 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0415656 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0403917 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0399467 |
| QKI | QKI, KH domain containing, RNA binding | -0.0395443 |
| C3 | complement component 3 | -0.0390037 |
| PRR16 | proline rich 16 | -0.0377142 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0367969 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0365004 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0362624 |
| CLMP | CXADR-like membrane protein | -0.0360981 |
| LOX | lysyl oxidase | -0.0355724 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0355173 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0354393 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0353671 |
| SMAD3 | SMAD family member 3 | -0.034926 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0347555 |
| TPM4 | tropomyosin 4 | -0.0338359 |
| BNC2 | basonuclin 2 | -0.0337064 |
| TENM2 | teneurin transmembrane protein 2 | -0.0336168 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0335842 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0333968 |
| VEGFA | vascular endothelial growth factor A | -0.0325975 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0324142 |
| EFNA5 | ephrin-A5 | -0.0324022 |
| LRRC7 | leucine rich repeat containing 7 | -0.0321865 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0316161 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0316094 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0314208 |
| BICC1 | BicC family RNA binding protein 1 | -0.0313748 |
| SBF2 | SET binding factor 2 | -0.0312872 |
| TPM1 | tropomyosin 1 (alpha) | -0.0312683 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0312238 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0310733 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0305412 |
| RAD51B | RAD51 paralog B | -0.0303377 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0300736 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.02962 |
| COL1A2 | collagen, type I, alpha 2 | -0.0295705 |
