| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capmatinib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capmatinib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.148544 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0812746 |
| IGF2 | insulin-like growth factor 2 | 0.0805457 |
| HLA-B | major histocompatibility complex, class I, B | 0.0763564 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0614891 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0539315 |
| KYNU | kynureninase | 0.0534771 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0495231 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0490091 |
| RPS8 | ribosomal protein S8 | 0.0485744 |
| INTS6 | integrator complex subunit 6 | 0.0463431 |
| EGFR | epidermal growth factor receptor | 0.041033 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0405625 |
| RPL37A | ribosomal protein L37a | 0.0398684 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0395638 |
| SEC24A | SEC24 family member A | 0.0348307 |
| MAP4 | microtubule-associated protein 4 | 0.0341218 |
| GOLGB1 | golgin B1 | 0.0338993 |
| EHBP1 | EH domain binding protein 1 | 0.033894 |
| BPTF | bromodomain PHD finger transcription factor | 0.0335112 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0315795 |
| RPS19 | ribosomal protein S19 | 0.0310208 |
| KAZN | kazrin, periplakin interacting protein | 0.030876 |
| RPS29 | ribosomal protein S29 | 0.0304491 |
| NRXN3 | neurexin 3 | 0.029911 |
| STC2 | stanniocalcin 2 | 0.0291945 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0283418 |
| RPL31 | ribosomal protein L31 | 0.0278135 |
| CALD1 | caldesmon 1 | 0.0278029 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0275278 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0273036 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0271466 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0267869 |
| RNF216 | ring finger protein 216 | 0.0267593 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0265583 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0260283 |
| PGM3 | phosphoglucomutase 3 | 0.0258974 |
| CANX | calnexin | 0.0256754 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0245798 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0244859 |
| HDAC9 | histone deacetylase 9 | 0.0242376 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.0242115 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0241923 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0241581 |
| UBAP2 | ubiquitin associated protein 2 | 0.0238086 |
| ATF4 | activating transcription factor 4 | 0.0236403 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0235667 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0235254 |
| RTN3 | reticulon 3 | 0.0230222 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.022958 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0228807 |
| RPL36 | ribosomal protein L36 | 0.0228421 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0225577 |
| RPL7A | ribosomal protein L7a | 0.0224399 |
| RPL19 | ribosomal protein L19 | 0.0222468 |
| DSTN | destrin (actin depolymerizing factor) | 0.0222101 |
| HOOK3 | hook microtubule-tethering protein 3 | 0.0221896 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0220408 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0218564 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.021662 |
| CEP95 | centrosomal protein 95kDa | 0.0215815 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0215476 |
| NDRG1 | N-myc downstream regulated 1 | 0.0213551 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0212263 |
| RPS17 | ribosomal protein S17 | 0.0210622 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.021 |
| COL5A1 | collagen, type V, alpha 1 | 0.0206821 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0205763 |
| VMP1 | vacuole membrane protein 1 | 0.0204667 |
| USO1 | USO1 vesicle transport factor | 0.0204617 |
| CUX1 | cut-like homeobox 1 | 0.0204574 |
| FTL | ferritin, light polypeptide | 0.0202138 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0201181 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0201136 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0199789 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | 0.0197829 |
| COX6C | cytochrome c oxidase subunit VIc | 0.0195691 |
| RPS25 | ribosomal protein S25 | 0.0194404 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0192966 |
| ENO1 | enolase 1, (alpha) | 0.0192612 |
| RACK1 | receptor for activated C kinase 1 | 0.0192105 |
| AAK1 | AP2 associated kinase 1 | 0.0192063 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0192051 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0192044 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0190562 |
| HIP1 | huntingtin interacting protein 1 | 0.0189949 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0189571 |
| RPS27A | ribosomal protein S27a | 0.0188368 |
| RPL35A | ribosomal protein L35a | 0.0188321 |
| SFTPA2 | surfactant protein A2 | 0.0188295 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.018803 |
| FLNA | filamin A, alpha | 0.0187618 |
| RPL26 | ribosomal protein L26 | 0.018734 |
| RPL5 | ribosomal protein L5 | 0.0186823 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0185921 |
| YEATS2 | YEATS domain containing 2 | 0.0185846 |
| OXSR1 | oxidative stress responsive 1 | 0.0184445 |
| PRELID2 | PRELI domain containing 2 | 0.0182815 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0181421 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | 0.017964 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.212318 |
| COL6A3 | collagen, type VI, alpha 3 | -0.205644 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.190156 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.149756 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.109138 |
| FN1 | fibronectin 1 | -0.105042 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0914567 |
| TMSB10 | thymosin beta 10 | -0.0819978 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0796387 |
| PRSS23 | protease, serine, 23 | -0.0766098 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0748571 |
| COL1A1 | collagen, type I, alpha 1 | -0.0706863 |
| MT1X | metallothionein 1X | -0.0697207 |
| MAP1B | microtubule-associated protein 1B | -0.0675481 |
| PTMA | prothymosin, alpha | -0.0615328 |
| HMGA2 | high mobility group AT-hook 2 | -0.0605754 |
| STC1 | stanniocalcin 1 | -0.0599356 |
| COL1A2 | collagen, type I, alpha 2 | -0.0529528 |
| EFNA5 | ephrin-A5 | -0.0523366 |
| CD44 | CD44 molecule (Indian blood group) | -0.0520159 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0517079 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0513364 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0500725 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0485033 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0484299 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0463727 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0450143 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0448896 |
| CCNI | cyclin I | -0.0435626 |
| LOXL2 | lysyl oxidase-like 2 | -0.0432655 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.043051 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0415487 |
| HMGB1 | high mobility group box 1 | -0.0411825 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0407481 |
| SDC4 | syndecan 4 | -0.0387142 |
| RRBP1 | ribosome binding protein 1 | -0.0374389 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0370032 |
| ANO6 | anoctamin 6 | -0.0361091 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0357132 |
| LOX | lysyl oxidase | -0.0356112 |
| NAV1 | neuron navigator 1 | -0.0352707 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0347173 |
| BSG | basigin (Ok blood group) | -0.0332673 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0331837 |
| TMSB4X | thymosin beta 4, X-linked | -0.0326959 |
| CD109 | CD109 molecule | -0.032402 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0316285 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0313375 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0312187 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0303736 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0303207 |
| CAVIN1 | caveolae associated protein 1 | -0.0301241 |
| COPA | coatomer protein complex, subunit alpha | -0.0299067 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0297583 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0294466 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0292063 |
| CLEC1B | C-type lectin domain family 1, member B | -0.028695 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | -0.0285207 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0284745 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0284421 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0282372 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0281691 |
| CD99 | CD99 molecule | -0.0277118 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0276372 |
| LMAN1 | lectin, mannose-binding, 1 | -0.027572 |
| ARF1 | ADP-ribosylation factor 1 | -0.0275051 |
| VIM | vimentin | -0.0274248 |
| CDH13 | cadherin 13 | -0.0273653 |
| TUBB | tubulin, beta class I | -0.0270661 |
| RPL28 | ribosomal protein L28 | -0.0264785 |
| ZNF292 | zinc finger protein 292 | -0.0264718 |
| RIGI | RNA sensor RIG-I | -0.0262802 |
| FMNL2 | formin-like 2 | -0.0260101 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0259333 |
| TNNC1 | troponin C type 1 (slow) | -0.0259032 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0257871 |
| TPX2 | TPX2, microtubule-associated | -0.0254599 |
| TAGLN2 | transgelin 2 | -0.0253733 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0252477 |
| HDAC8 | histone deacetylase 8 | -0.0249263 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0248061 |
| SYNJ2 | synaptojanin 2 | -0.0247248 |
| AFAP1 | actin filament associated protein 1 | -0.0245137 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0244863 |
| VEGFA | vascular endothelial growth factor A | -0.0244693 |
| GLIS3 | GLIS family zinc finger 3 | -0.0244657 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0244472 |
| RPLP1 | ribosomal protein, large, P1 | -0.0243787 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0240829 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0240763 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0240354 |
| RLF | rearranged L-myc fusion | -0.0239742 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0238328 |
| B2M | beta-2-microglobulin | -0.0237728 |
| LDHA | lactate dehydrogenase A | -0.0237605 |
| TUBA1B | tubulin, alpha 1b | -0.023589 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0234578 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0234107 |
| CDK6 | cyclin-dependent kinase 6 | -0.0234092 |
| H3-3B | H3.3 histone B | -0.0230746 |
