| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capmatinib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capmatinib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SQSTM1 | sequestosome 1 | 0.0902931 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0782674 |
| INTS6 | integrator complex subunit 6 | 0.0752681 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0620513 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0517248 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0500268 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0436937 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0380936 |
| IL6ST | interleukin 6 signal transducer | 0.0378792 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0376606 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0366904 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0352292 |
| GPHN | gephyrin | 0.0350448 |
| TXNRD1 | thioredoxin reductase 1 | 0.0347587 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0337289 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0334274 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0328634 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0325563 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.031482 |
| BRD2 | bromodomain containing 2 | 0.0313829 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0305117 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0295541 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0278489 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0269639 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0260603 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0257043 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0252726 |
| DENND4A | DENN/MADD domain containing 4A | 0.0246904 |
| CALR | calreticulin | 0.0241738 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0241529 |
| TLE4 | transducin-like enhancer of split 4 | 0.0240031 |
| RPL36 | ribosomal protein L36 | 0.0239868 |
| RPS12 | ribosomal protein S12 | 0.0238107 |
| CREBBP | CREB binding protein | 0.0238079 |
| SIK2 | salt-inducible kinase 2 | 0.0235058 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0234711 |
| CENPP | centromere protein P | 0.0234462 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0233077 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0230296 |
| AEBP2 | AE binding protein 2 | 0.0227461 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0226003 |
| ATP10D | ATPase, class V, type 10D | 0.0224912 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0224244 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.021502 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0213524 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.021191 |
| ATF3 | activating transcription factor 3 | 0.0211814 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0211465 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0211067 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0210828 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0210646 |
| TXNIP | thioredoxin interacting protein | 0.021029 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0210187 |
| RPS3 | ribosomal protein S3 | 0.0209199 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0208482 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0207761 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0206283 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0206219 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0205497 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0203188 |
| PCNX2 | pecanex 2 | 0.0202977 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0202112 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0200707 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0199043 |
| UBAP2 | ubiquitin associated protein 2 | 0.0197919 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0196082 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0195723 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0195456 |
| SUCLA2 | succinate-CoA ligase, ADP-forming, beta subunit | 0.0193148 |
| LRRC49 | leucine rich repeat containing 49 | 0.0192723 |
| JMJD1C | jumonji domain containing 1C | 0.0192438 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0192437 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0191366 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.0190087 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0189405 |
| MED13L | mediator complex subunit 13-like | 0.0188665 |
| TOP1 | topoisomerase (DNA) I | 0.0187052 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0186382 |
| ARRDC3 | arrestin domain containing 3 | 0.0184942 |
| ACYP2 | acylphosphatase 2, muscle type | 0.0184004 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0182541 |
| TNPO1 | transportin 1 | 0.0181774 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0181159 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0180745 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 0.0180544 |
| UBQLN1 | ubiquilin 1 | 0.0180336 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0179535 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0179276 |
| CEP295 | centrosomal protein 295kDa | 0.0178643 |
| AGPS | alkylglycerone phosphate synthase | 0.0178452 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0178159 |
| TOB1 | transducer of ERBB2, 1 | 0.0177551 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0177546 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0177242 |
| CEP290 | centrosomal protein 290kDa | 0.0174758 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0174631 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0173985 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 | 0.0173884 |
| ZNF24 | zinc finger protein 24 | 0.0173773 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0172655 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.255543 |
| VIM | vimentin | -0.189589 |
| FNDC3B | fibronectin type III domain containing 3B | -0.154346 |
| TMSB10 | thymosin beta 10 | -0.133005 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.101327 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0982476 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.09757 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0969937 |
| DNER | delta/notch-like EGF repeat containing | -0.0938884 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0933568 |
| PTMA | prothymosin, alpha | -0.0826598 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0824075 |
| CD44 | CD44 molecule (Indian blood group) | -0.0822674 |
| MT2A | metallothionein 2A | -0.0795349 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0782361 |
| NDRG1 | N-myc downstream regulated 1 | -0.077701 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0763696 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0740599 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0716367 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0696311 |
| POTEF | POTE ankyrin domain family, member F | -0.0664294 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0661104 |
| ANGPTL4 | angiopoietin-like 4 | -0.0644935 |
| CAPRIN2 | caprin family member 2 | -0.0640342 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0639319 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0637798 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0628261 |
| FLNB | filamin B, beta | -0.0620877 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0613543 |
| ERBIN | erbb2 interacting protein | -0.0613043 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0602366 |
| ASPH | aspartate beta-hydroxylase | -0.0598302 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0595144 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0591447 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.057761 |
| MSN | moesin | -0.0574627 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.056238 |
| HMGA2 | high mobility group AT-hook 2 | -0.0561955 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.056144 |
| ATXN1 | ataxin 1 | -0.0551468 |
| YBX3 | Y box binding protein 3 | -0.0539322 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0522743 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0510362 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0499479 |
| RAI14 | retinoic acid induced 14 | -0.0497711 |
| PYGL | phosphorylase, glycogen, liver | -0.0492929 |
| TPM4 | tropomyosin 4 | -0.0491903 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0489741 |
| NALCN | sodium leak channel, non selective | -0.0485816 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0478069 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0476812 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0470683 |
| FMN1 | formin 1 | -0.0449981 |
| EFNA5 | ephrin-A5 | -0.044355 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0443156 |
| ATP13A3 | ATPase type 13A3 | -0.0443022 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0442737 |
| MYO9B | myosin IXB | -0.0441583 |
| MAP1B | microtubule-associated protein 1B | -0.043922 |
| IGF2 | insulin-like growth factor 2 | -0.0437218 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0433299 |
| FMNL2 | formin-like 2 | -0.0431792 |
| SETD5 | SET domain containing 5 | -0.0430392 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0429545 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0424979 |
| GPC6 | glypican 6 | -0.0422798 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0411636 |
| PFN1 | profilin 1 | -0.039324 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.039186 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0388834 |
| ACTG1 | actin gamma 1 | -0.0385951 |
| DEK | DEK proto-oncogene | -0.0385856 |
| ATG7 | autophagy related 7 | -0.0381364 |
| MCL1 | myeloid cell leukemia 1 | -0.0380521 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0380021 |
| IER3 | immediate early response 3 | -0.0377365 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0372779 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0372209 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0369895 |
| LDHA | lactate dehydrogenase A | -0.0367303 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.036722 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0362546 |
| RIN2 | Ras and Rab interactor 2 | -0.0362536 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.035797 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0357807 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0356775 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0352979 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0351521 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0350799 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0350746 |
| DOCK4 | dedicator of cytokinesis 4 | -0.034975 |
| PKM | pyruvate kinase, muscle | -0.0345249 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0340196 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0337716 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0335746 |
| PRSS23 | protease, serine, 23 | -0.0334534 |
| NGLY1 | N-glycanase 1 | -0.0324579 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.032354 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0323377 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0320703 |
