| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Captopril_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0878851 |
| RPL23 | ribosomal protein L23 | 0.0696241 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0682319 |
| PTMA | prothymosin, alpha | 0.0641312 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.059533 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0513898 |
| FAM13A | family with sequence similarity 13, member A | 0.0488634 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0469365 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0462 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0454313 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0453836 |
| FNBP1 | formin binding protein 1 | 0.0434044 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0432544 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0431846 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.042949 |
| TLE4 | transducin-like enhancer of split 4 | 0.0424114 |
| OGA | O-GlcNAcase | 0.0414613 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0408096 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0398206 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.037945 |
| FOXO3 | forkhead box O3 | 0.0366678 |
| MEIS2 | Meis homeobox 2 | 0.0363817 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0362713 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0356016 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0355599 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0349928 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0348794 |
| SET | SET nuclear proto-oncogene | 0.0346965 |
| HELZ | helicase with zinc finger | 0.0344995 |
| KLHL13 | kelch-like family member 13 | 0.033678 |
| XPO1 | exportin 1 | 0.0334607 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0331876 |
| AOPEP | aminopeptidase O (putative) | 0.0322198 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0320992 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.031446 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0311055 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0309766 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.030436 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0303537 |
| ZNF292 | zinc finger protein 292 | 0.0300447 |
| RPL19 | ribosomal protein L19 | 0.0295891 |
| FMN1 | formin 1 | 0.0295106 |
| NEK7 | NIMA-related kinase 7 | 0.0289989 |
| DST | dystonin | 0.0289333 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0286638 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0284482 |
| NCKAP1 | NCK-associated protein 1 | 0.0284402 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0279071 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0279037 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0276472 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0272388 |
| HAS2 | hyaluronan synthase 2 | 0.0272109 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0270743 |
| HMGB2 | high mobility group box 2 | 0.0268108 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0265987 |
| TBX2 | T-box 2 | 0.0265631 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0258491 |
| ZFR | zinc finger RNA binding protein | 0.0256676 |
| RNF145 | ring finger protein 145 | 0.0256644 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0256219 |
| RPS12 | ribosomal protein S12 | 0.0253711 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0253154 |
| RYBP | RING1 and YY1 binding protein | 0.0250812 |
| SBF2 | SET binding factor 2 | 0.0249611 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0246914 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0244876 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0243986 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0241976 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0241915 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0241423 |
| MKI67 | marker of proliferation Ki-67 | 0.0241315 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0240035 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0239378 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0235547 |
| CDC73 | cell division cycle 73 | 0.0235316 |
| RPL31 | ribosomal protein L31 | 0.0231164 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0224441 |
| SLMAP | sarcolemma associated protein | 0.022255 |
| VIM | vimentin | 0.0219637 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0219586 |
| SEPTIN7 | septin 7 | 0.0217372 |
| ARRDC3 | arrestin domain containing 3 | 0.0216408 |
| CDC27 | cell division cycle 27 | 0.0216074 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0215166 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0213671 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0212723 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0209975 |
| PHOX2B | paired-like homeobox 2b | 0.0209901 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0207748 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0206093 |
| MRTFA | myocardin related transcription factor A | 0.0205977 |
| YME1L1 | YME1-like 1 ATPase | 0.0205898 |
| RBM27 | RNA binding motif protein 27 | 0.0205876 |
| WDR43 | WD repeat domain 43 | 0.0203857 |
| ETNK1 | ethanolamine kinase 1 | 0.0203651 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0203329 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0202317 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0202277 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0202216 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0201932 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.185563 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.121851 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0805826 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0796682 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0794034 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0671438 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0665313 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0660688 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0637936 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.06021 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0586521 |
| PRKCA | protein kinase C, alpha | -0.0573349 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0552671 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0531516 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0527667 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0507334 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.049907 |
| NDRG1 | N-myc downstream regulated 1 | -0.0470205 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0461547 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0459627 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0456274 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0451123 |
| EXOC4 | exocyst complex component 4 | -0.04484 |
| MCL1 | myeloid cell leukemia 1 | -0.044746 |
| CDH13 | cadherin 13 | -0.0441594 |
| CUX1 | cut-like homeobox 1 | -0.0433834 |
| ACTG1 | actin gamma 1 | -0.0429294 |
| GDF15 | growth differentiation factor 15 | -0.0427749 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0421454 |
| KCNIP4 | Kv channel interacting protein 4 | -0.0412904 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0411203 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0410336 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0393672 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0393657 |
| COL1A1 | collagen, type I, alpha 1 | -0.039013 |
| ZNF638 | zinc finger protein 638 | -0.0380783 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0378725 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0377881 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0373411 |
| FN1 | fibronectin 1 | -0.0360396 |
| CADM1 | cell adhesion molecule 1 | -0.0356533 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0341809 |
| EGR1 | early growth response 1 | -0.0341435 |
| HMGA2 | high mobility group AT-hook 2 | -0.0334753 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0334751 |
| USP34 | ubiquitin specific peptidase 34 | -0.0329039 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0319736 |
| GPC5 | glypican 5 | -0.0311805 |
| BPTF | bromodomain PHD finger transcription factor | -0.0310215 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0303627 |
| CADM2 | cell adhesion molecule 2 | -0.0301633 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0299212 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0298604 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0296586 |
| COL4A6 | collagen, type IV, alpha 6 | -0.0295403 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0295083 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0293078 |
| TCF12 | transcription factor 12 | -0.0290551 |
| ZNF804A | zinc finger protein 804A | -0.0288753 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0288525 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0284997 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0283856 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.027975 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.027937 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0275555 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0267941 |
| ADAMTS19 | ADAM metallopeptidase with thrombospondin type 1 motif, 19 | -0.0265933 |
| AFF3 | AF4/FMR2 family, member 3 | -0.026349 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0261638 |
| ARF4 | ADP-ribosylation factor 4 | -0.0259582 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0258651 |
| SEPTIN9 | septin 9 | -0.0258528 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0256389 |
| IGF2 | insulin-like growth factor 2 | -0.0254311 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0253147 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0248258 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0247099 |
| ZFHX3 | zinc finger homeobox 3 | -0.0243751 |
| NBEA | neurobeachin | -0.0243337 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0242559 |
| COPA | coatomer protein complex, subunit alpha | -0.024155 |
| HM13 | histocompatibility (minor) 13 | -0.0241428 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0241381 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.024105 |
| MSI2 | musashi RNA-binding protein 2 | -0.0239404 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0239026 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.02382 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0237336 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0237266 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0236917 |
| IER3 | immediate early response 3 | -0.0236857 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0236013 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0230962 |
| CNTN4 | contactin 4 | -0.023057 |
| CCDC91 | coiled-coil domain containing 91 | -0.0229519 |
| PLAT | plasminogen activator, tissue | -0.0225112 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0223313 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.022283 |
| CTBP2 | C-terminal binding protein 2 | -0.0222569 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.0221721 |
