| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Captopril_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP13A3 | ATPase type 13A3 | 0.155566 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.13509 |
| EXT1 | exostosin glycosyltransferase 1 | 0.132679 |
| VEGFA | vascular endothelial growth factor A | 0.114926 |
| SPAG9 | sperm associated antigen 9 | 0.079094 |
| RPL5 | ribosomal protein L5 | 0.0757469 |
| STC1 | stanniocalcin 1 | 0.0722197 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0718124 |
| RPS8 | ribosomal protein S8 | 0.0678228 |
| ANXA5 | annexin A5 | 0.0599736 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0579472 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0578029 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0572209 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0551984 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0549671 |
| RASA2 | RAS p21 protein activator 2 | 0.0528786 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0504717 |
| MRTFA | myocardin related transcription factor A | 0.0479584 |
| LOX | lysyl oxidase | 0.0469177 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0469174 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0463844 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0461325 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0445428 |
| TFG | TRK-fused gene | 0.0444243 |
| COL5A1 | collagen, type V, alpha 1 | 0.0442827 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0429507 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0422212 |
| RPS3 | ribosomal protein S3 | 0.0419877 |
| RPL13A | ribosomal protein L13a | 0.0415453 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0396375 |
| RPS6 | ribosomal protein S6 | 0.0393435 |
| RPL26 | ribosomal protein L26 | 0.039225 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0383418 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0381324 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0377086 |
| ZNF292 | zinc finger protein 292 | 0.0374399 |
| PDE10A | phosphodiesterase 10A | 0.0373531 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0373468 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0371846 |
| MT2A | metallothionein 2A | 0.0369462 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0367467 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0366288 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0365183 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0364978 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0362681 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0357387 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0355811 |
| MYO9B | myosin IXB | 0.0355394 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0351796 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0351396 |
| S100A9 | S100 calcium binding protein A9 | 0.0349747 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0348836 |
| POSTN | periostin, osteoblast specific factor | 0.0348719 |
| CAVIN1 | caveolae associated protein 1 | 0.0342083 |
| SDC2 | syndecan 2 | 0.0342022 |
| TMEM165 | transmembrane protein 165 | 0.0338672 |
| RPL7 | ribosomal protein L7 | 0.0337685 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0337072 |
| MTSS1 | metastasis suppressor 1 | 0.0332256 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0328626 |
| HM13 | histocompatibility (minor) 13 | 0.0327422 |
| RACK1 | receptor for activated C kinase 1 | 0.0322498 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0320336 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0320201 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0319848 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0319019 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0316214 |
| ANXA2 | annexin A2 | 0.031461 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0314474 |
| RPL30 | ribosomal protein L30 | 0.0312333 |
| COG5 | component of oligomeric golgi complex 5 | 0.0310045 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0309841 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0309768 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0308534 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0308154 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0308113 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0307014 |
| DENND5A | DENN/MADD domain containing 5A | 0.0306908 |
| CALU | calumenin | 0.0302498 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0302443 |
| GOLT1B | golgi transport 1B | 0.0293635 |
| GOLGA4 | golgin A4 | 0.0293384 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0291173 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0290342 |
| CDH13 | cadherin 13 | 0.0286864 |
| INHBA | inhibin, beta A | 0.0286707 |
| EGFR | epidermal growth factor receptor | 0.0286187 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0285588 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0284267 |
| FOXJ3 | forkhead box J3 | 0.0284073 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0283881 |
| RND3 | Rho family GTPase 3 | 0.0282841 |
| NAV2 | neuron navigator 2 | 0.0278894 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0278227 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0278007 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0277217 |
| RLF | rearranged L-myc fusion | 0.0275594 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0275117 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0274906 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0273114 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.323394 |
| COL6A3 | collagen, type VI, alpha 3 | -0.198353 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.177007 |
| TMSB10 | thymosin beta 10 | -0.128216 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.108062 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.100067 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0879746 |
| AHNAK | AHNAK nucleoprotein | -0.0806198 |
| CANX | calnexin | -0.0744958 |
| MAP1B | microtubule-associated protein 1B | -0.0713879 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0653062 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0616304 |
| ASPH | aspartate beta-hydroxylase | -0.05795 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0533332 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0505311 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0500496 |
| COL1A1 | collagen, type I, alpha 1 | -0.0487515 |
| FBN1 | fibrillin 1 | -0.0484606 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0459424 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0458638 |
| MT1X | metallothionein 1X | -0.0450917 |
| HLA-A | major histocompatibility complex, class I, A | -0.043586 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0434557 |
| LOXL2 | lysyl oxidase-like 2 | -0.0401968 |
| YBX1 | Y box binding protein 1 | -0.0395451 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0369696 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0340748 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0324151 |
| HYOU1 | hypoxia up-regulated 1 | -0.0314538 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0312242 |
| EGR1 | early growth response 1 | -0.03115 |
| TAPBP | TAP binding protein (tapasin) | -0.0310039 |
| OPTN | optineurin | -0.0301958 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0296001 |
| NRP1 | neuropilin 1 | -0.0295726 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0286069 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0281029 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0277136 |
| CCNL1 | cyclin L1 | -0.0273127 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0259893 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0256115 |
| RPL35A | ribosomal protein L35a | -0.0255051 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0253925 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0253139 |
| PGK1 | phosphoglycerate kinase 1 | -0.0245806 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0245653 |
| ATL1 | atlastin GTPase 1 | -0.024169 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.024131 |
| PKM | pyruvate kinase, muscle | -0.0232256 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0232244 |
| NREP | neuronal regeneration related protein | -0.0232145 |
| RPS19 | ribosomal protein S19 | -0.0226611 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0224641 |
| H1-0 | H1.0 linker histone | -0.0224548 |
| JUN | jun proto-oncogene | -0.0214432 |
| SP100 | SP100 nuclear antigen | -0.0207604 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0204727 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0204631 |
| TPM4 | tropomyosin 4 | -0.0204479 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0204399 |
| BBX | bobby sox homolog (Drosophila) | -0.0199118 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0197186 |
| COL1A2 | collagen, type I, alpha 2 | -0.0196534 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0196491 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0195717 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0195036 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0193326 |
| MX2 | MX dynamin-like GTPase 2 | -0.0187206 |
| LAMB1 | laminin, beta 1 | -0.0186426 |
| MYO1B | myosin IB | -0.0185215 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0184615 |
| TENM3 | teneurin transmembrane protein 3 | -0.0183623 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | -0.0183349 |
| IFI44 | interferon-induced protein 44 | -0.0182535 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | -0.017909 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.017897 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.01767 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0175664 |
| GNAS | GNAS complex locus | -0.0173796 |
| PERP | PERP, TP53 apoptosis effector | -0.0171931 |
| PRELID2 | PRELI domain containing 2 | -0.0169998 |
| PCDH7 | protocadherin 7 | -0.0168314 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0168208 |
| STC2 | stanniocalcin 2 | -0.0167701 |
| RPL3 | ribosomal protein L3 | -0.0167692 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0167664 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0167229 |
| TPM2 | tropomyosin 2 (beta) | -0.0167124 |
| PLEC | plectin | -0.0166404 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0165978 |
| UTRN | utrophin | -0.0164618 |
| DSPP | dentin sialophosphoprotein | -0.0164555 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0163939 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0163663 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0163298 |
| EXOC4 | exocyst complex component 4 | -0.0161761 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0161588 |
| PLSCR1 | phospholipid scramblase 1 | -0.016072 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0160531 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0160429 |
