| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Captopril_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.141555 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.134922 |
| TF | transferrin | 0.109699 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.102873 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0839304 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0803772 |
| RPS12 | ribosomal protein S12 | 0.0755808 |
| TRIM26 | tripartite motif containing 26 | 0.0751228 |
| GPC3 | glypican 3 | 0.0659271 |
| ANXA5 | annexin A5 | 0.0596975 |
| AFDN | afadin, adherens junction formation factor | 0.0589034 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0544857 |
| VEGFA | vascular endothelial growth factor A | 0.0539323 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0502719 |
| RPL5 | ribosomal protein L5 | 0.0469594 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.046468 |
| RBM25 | RNA binding motif protein 25 | 0.0454086 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0450852 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0420796 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0420209 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0418132 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0414129 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0385456 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0381403 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0365955 |
| VMP1 | vacuole membrane protein 1 | 0.0352537 |
| LRRC1 | leucine rich repeat containing 1 | 0.0346636 |
| TOP1 | topoisomerase (DNA) I | 0.0344895 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0341999 |
| SELENOP | selenoprotein P | 0.0341382 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.033702 |
| NCKAP1 | NCK-associated protein 1 | 0.0336363 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.03322 |
| MTSS1 | metastasis suppressor 1 | 0.0327838 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0325721 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0322729 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0320948 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0320058 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0312032 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0305772 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0301599 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0300453 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0299525 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0292559 |
| MALT1 | MALT1 paracaspase | 0.0292099 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0291536 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0289502 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0286487 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0284925 |
| CFB | complement factor B | 0.0284313 |
| FOXO1 | forkhead box O1 | 0.0282228 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0281939 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0280386 |
| OGA | O-GlcNAcase | 0.0279157 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0277526 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0275684 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0275415 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0271485 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.0271125 |
| ZNF292 | zinc finger protein 292 | 0.0270423 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0269004 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0268598 |
| SMAD5 | SMAD family member 5 | 0.0268233 |
| HELZ | helicase with zinc finger | 0.0267704 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0267092 |
| PDE8A | phosphodiesterase 8A | 0.0266232 |
| CPE | carboxypeptidase E | 0.0261007 |
| SPAG9 | sperm associated antigen 9 | 0.0260704 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0258088 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.025733 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0256254 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0249408 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0248996 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0247583 |
| WDR43 | WD repeat domain 43 | 0.0241353 |
| RPS27A | ribosomal protein S27a | 0.024089 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0239566 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0239368 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0238455 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0236632 |
| WTAP | Wilms tumor 1 associated protein | 0.0235993 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0235848 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0235458 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0232864 |
| CDK19 | cyclin-dependent kinase 19 | 0.0229527 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0226936 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0226164 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0225407 |
| USP3 | ubiquitin specific peptidase 3 | 0.0225208 |
| PHIP | pleckstrin homology domain interacting protein | 0.0224552 |
| RPS3 | ribosomal protein S3 | 0.0223505 |
| BCL2L1 | BCL2-like 1 | 0.0223208 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0222591 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0221683 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0220334 |
| FNIP1 | folliculin interacting protein 1 | 0.0220018 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0219565 |
| SBF2 | SET binding factor 2 | 0.0219308 |
| SET | SET nuclear proto-oncogene | 0.0219005 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0218768 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.201933 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.176037 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.175453 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.161129 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.121453 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.113793 |
| PEG3 | paternally expressed 3 | -0.112043 |
| DSPP | dentin sialophosphoprotein | -0.0853605 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0740556 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0691438 |
| EGR1 | early growth response 1 | -0.0684341 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.067873 |
| CP | ceruloplasmin (ferroxidase) | -0.0666002 |
| C3 | complement component 3 | -0.0654095 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0646363 |
| ASPH | aspartate beta-hydroxylase | -0.0633714 |
| GPC6 | glypican 6 | -0.0627816 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0622988 |
| H1-0 | H1.0 linker histone | -0.0619027 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0607369 |
| TMSB10 | thymosin beta 10 | -0.0604129 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0600814 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.057999 |
| ATXN1 | ataxin 1 | -0.0561164 |
| PLIN2 | perilipin 2 | -0.0559219 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0522619 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0513793 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0509171 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0505577 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0498669 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0491743 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0449123 |
| RNF213 | ring finger protein 213 | -0.0438317 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0415858 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.041476 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0411155 |
| EHBP1 | EH domain binding protein 1 | -0.0398924 |
| GSE1 | Gse1 coiled-coil protein | -0.0398119 |
| AHSG | alpha-2-HS-glycoprotein | -0.0392441 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0390572 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0388836 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0384197 |
| ENO1 | enolase 1, (alpha) | -0.0373864 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0372898 |
| MAP1B | microtubule-associated protein 1B | -0.0371915 |
| OSMR | oncostatin M receptor | -0.036138 |
| ACTG1 | actin gamma 1 | -0.035843 |
| TPM4 | tropomyosin 4 | -0.0349764 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0348886 |
| PKM | pyruvate kinase, muscle | -0.0348761 |
| MCL1 | myeloid cell leukemia 1 | -0.033926 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0333524 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.0333376 |
| ZFHX3 | zinc finger homeobox 3 | -0.0332453 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0327491 |
| UTRN | utrophin | -0.0326339 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0324072 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0322656 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0319122 |
| CANX | calnexin | -0.0315624 |
| UBC | ubiquitin C | -0.031306 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0312155 |
| TFRC | transferrin receptor | -0.0308843 |
| TXNRD1 | thioredoxin reductase 1 | -0.0306468 |
| FAT1 | FAT atypical cadherin 1 | -0.0305409 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.030411 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0303605 |
| SVIL | supervillin | -0.0293134 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0289444 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.028322 |
| PTCHD4 | patched domain containing 4 | -0.0281732 |
| KRT8 | keratin 8, type II | -0.0280303 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0276599 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0273825 |
| KRT23 | keratin 23, type I | -0.0272734 |
| CRLS1 | cardiolipin synthase 1 | -0.0270364 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0259703 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0254947 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0248665 |
| AAK1 | AP2 associated kinase 1 | -0.0244949 |
| TNS3 | tensin 3 | -0.0238238 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0237308 |
| KIAA1217 | KIAA1217 | -0.0234579 |
| KRT18 | keratin 18, type I | -0.0231141 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0228661 |
| RPLP0 | ribosomal protein, large, P0 | -0.0225478 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0224076 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0223226 |
| KYNU | kynureninase | -0.0222073 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0220955 |
| RNASET2 | ribonuclease T2 | -0.0220928 |
| TCIM | transcriptional and immune response regulator | -0.0220887 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0220784 |
| SH3PXD2A | SH3 and PX domains 2A | -0.0216466 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0216129 |
| POTEF | POTE ankyrin domain family, member F | -0.0213878 |
| PKP4 | plakophilin 4 | -0.0213764 |
| CDV3 | CDV3 homolog (mouse) | -0.0213336 |
| JUN | jun proto-oncogene | -0.0212823 |
| DUSP16 | dual specificity phosphatase 16 | -0.0211501 |
