| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Captopril_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.17744 |
| MEF2A | myocyte enhancer factor 2A | 0.109728 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0845871 |
| MTSS1 | metastasis suppressor 1 | 0.0819534 |
| FOXO1 | forkhead box O1 | 0.0705532 |
| MSN | moesin | 0.0678498 |
| BCL2L1 | BCL2-like 1 | 0.0655193 |
| ITGA6 | integrin, alpha 6 | 0.0632352 |
| CLU | clusterin | 0.0614585 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0608142 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0571181 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0554434 |
| GOLGA4 | golgin A4 | 0.0546469 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0523314 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0492279 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0489805 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.048948 |
| ANXA5 | annexin A5 | 0.0484052 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0479115 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0477157 |
| B2M | beta-2-microglobulin | 0.0472264 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0471728 |
| SPAG9 | sperm associated antigen 9 | 0.046536 |
| FOSL1 | FOS-like antigen 1 | 0.0459568 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0449939 |
| MYOF | myoferlin | 0.0448296 |
| OGA | O-GlcNAcase | 0.0425587 |
| ZNF292 | zinc finger protein 292 | 0.0424018 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0420286 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0418381 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0409246 |
| RIN2 | Ras and Rab interactor 2 | 0.0400942 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0400548 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0392334 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0374786 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0368576 |
| RNF145 | ring finger protein 145 | 0.0367698 |
| TPM3 | tropomyosin 3 | 0.0365946 |
| STC1 | stanniocalcin 1 | 0.0358774 |
| SETD5 | SET domain containing 5 | 0.0354277 |
| KIAA1217 | KIAA1217 | 0.0354091 |
| MYO10 | myosin X | 0.0353489 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.034892 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0347931 |
| CD99 | CD99 molecule | 0.0340756 |
| CAPRIN2 | caprin family member 2 | 0.0338929 |
| ARRDC3 | arrestin domain containing 3 | 0.0327835 |
| LUZP1 | leucine zipper protein 1 | 0.0322652 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0321279 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0317499 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0315291 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0313229 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0312013 |
| SQLE | squalene epoxidase | 0.0311289 |
| ATP13A3 | ATPase type 13A3 | 0.0307403 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0306562 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0296321 |
| PLAT | plasminogen activator, tissue | 0.0294879 |
| FNIP1 | folliculin interacting protein 1 | 0.029435 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0293692 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0291536 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.029117 |
| TMEM165 | transmembrane protein 165 | 0.0287774 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0283108 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0282026 |
| SBF2 | SET binding factor 2 | 0.0281954 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0280833 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0280808 |
| XPO1 | exportin 1 | 0.0280548 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0279202 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0276404 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0274639 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0273344 |
| SLMAP | sarcolemma associated protein | 0.0269741 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0267674 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0265996 |
| DSTN | destrin (actin depolymerizing factor) | 0.0263562 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0261352 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0261207 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0259756 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0258524 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0255383 |
| SUCO | SUN domain containing ossification factor | 0.0255255 |
| NUP58 | nucleoporin 58 | 0.02547 |
| VCL | vinculin | 0.0253823 |
| SEC24A | SEC24 family member A | 0.0252865 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0252382 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0251619 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0250809 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0248467 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0246597 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0246195 |
| CALU | calumenin | 0.0246085 |
| NRG1 | neuregulin 1 | 0.0245966 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0245318 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0244345 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0242094 |
| HDGF | hepatoma-derived growth factor | 0.0241968 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0237762 |
| PLS3 | plastin 3 | 0.0237083 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.220627 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.157023 |
| TMSB10 | thymosin beta 10 | -0.126291 |
| AHNAK | AHNAK nucleoprotein | -0.10887 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.108025 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0855076 |
| LMO7 | LIM domain 7 | -0.0838531 |
| H1-0 | H1.0 linker histone | -0.070462 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0661961 |
| INTS6 | integrator complex subunit 6 | -0.056053 |
| TMSB4X | thymosin beta 4, X-linked | -0.0513877 |
| GNAS | GNAS complex locus | -0.0503647 |
| RPLP1 | ribosomal protein, large, P1 | -0.0498495 |
| CANX | calnexin | -0.0485645 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0456439 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0438768 |
| RPS19 | ribosomal protein S19 | -0.0426317 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0422237 |
| RPS24 | ribosomal protein S24 | -0.0414507 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0404176 |
| ARF1 | ADP-ribosylation factor 1 | -0.0400654 |
| RPL11 | ribosomal protein L11 | -0.0396295 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0389836 |
| RPL35A | ribosomal protein L35a | -0.0375932 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0361012 |
| LDHA | lactate dehydrogenase A | -0.0353836 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0351089 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0334988 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.032848 |
| RPL34 | ribosomal protein L34 | -0.0326333 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0326281 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0324936 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.032447 |
| PLEC | plectin | -0.0319539 |
| RRBP1 | ribosome binding protein 1 | -0.0316706 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0298397 |
| MT1X | metallothionein 1X | -0.0276199 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0269289 |
| HLA-B | major histocompatibility complex, class I, B | -0.0269262 |
| ACTG1 | actin gamma 1 | -0.0268707 |
| RIGI | RNA sensor RIG-I | -0.0267375 |
| RPL8 | ribosomal protein L8 | -0.0262278 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0261128 |
| HDLBP | high density lipoprotein binding protein | -0.0260568 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0257175 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0251913 |
| S100A10 | S100 calcium binding protein A10 | -0.0251648 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0246951 |
| RPS20 | ribosomal protein S20 | -0.024315 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0239142 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0236729 |
| RPS4X | ribosomal protein S4, X-linked | -0.0236252 |
| RPLP0 | ribosomal protein, large, P0 | -0.0235846 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.023216 |
| PALLD | palladin, cytoskeletal associated protein | -0.0228815 |
| THBD | thrombomodulin | -0.0226502 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0224634 |
| FN1 | fibronectin 1 | -0.0224505 |
| IER3 | immediate early response 3 | -0.0220846 |
| LMNA | lamin A/C | -0.0220448 |
| KRT17 | keratin 17, type I | -0.0219905 |
| SDC4 | syndecan 4 | -0.0213819 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0212966 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0210896 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0210206 |
| YBX1 | Y box binding protein 1 | -0.020816 |
| EGR1 | early growth response 1 | -0.0207337 |
| MT2A | metallothionein 2A | -0.0206372 |
| SP100 | SP100 nuclear antigen | -0.0206042 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0199643 |
| FTL | ferritin, light polypeptide | -0.0198712 |
| RPS21 | ribosomal protein S21 | -0.0198236 |
| RPL28 | ribosomal protein L28 | -0.0198099 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0194369 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0194076 |
| POTEF | POTE ankyrin domain family, member F | -0.0193979 |
| S100A4 | S100 calcium binding protein A4 | -0.0193609 |
| RPS14 | ribosomal protein S14 | -0.0193432 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0192956 |
| ACTN4 | actinin, alpha 4 | -0.0191693 |
| HLA-C | major histocompatibility complex, class I, C | -0.0187749 |
| GM2A | GM2 ganglioside activator | -0.0187723 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0187117 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0181975 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.017881 |
| PLTP | phospholipid transfer protein | -0.0178708 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0178296 |
| MECOM | MDS1 and EVI1 complex locus | -0.0177933 |
| RPS23 | ribosomal protein S23 | -0.0177379 |
| PGK1 | phosphoglycerate kinase 1 | -0.0176378 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0171803 |
| ANXA1 | annexin A1 | -0.0170616 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0169055 |
| RPL30 | ribosomal protein L30 | -0.0168761 |
| ADIRF | adipogenesis regulatory factor | -0.0168727 |
| TNS3 | tensin 3 | -0.0164606 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0162325 |
| HMGB1 | high mobility group box 1 | -0.0162028 |
| EFNA5 | ephrin-A5 | -0.0161243 |
| RPL27A | ribosomal protein L27a | -0.0161197 |
