| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Captopril_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.126393 |
| TXNIP | thioredoxin interacting protein | 0.106287 |
| AREG | amphiregulin | 0.104653 |
| EREG | epiregulin | 0.102206 |
| RNF145 | ring finger protein 145 | 0.0985862 |
| VEGFA | vascular endothelial growth factor A | 0.0952393 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0833623 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0822662 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0750836 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.072872 |
| ANXA2 | annexin A2 | 0.0725909 |
| ONECUT3 | one cut homeobox 3 | 0.072556 |
| FLNB | filamin B, beta | 0.0714472 |
| ITGA6 | integrin, alpha 6 | 0.0693978 |
| NDRG1 | N-myc downstream regulated 1 | 0.0691352 |
| RBM39 | RNA binding motif protein 39 | 0.0651318 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0640277 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0634931 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0605117 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0597782 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.059121 |
| FAM13A | family with sequence similarity 13, member A | 0.0587768 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0576514 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.056981 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0569619 |
| PDLIM5 | PDZ and LIM domain 5 | 0.056624 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0561373 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0540557 |
| HMGA1 | high mobility group AT-hook 1 | 0.0538579 |
| MED13L | mediator complex subunit 13-like | 0.0511555 |
| MYO1E | myosin IE | 0.0509051 |
| PCBP2 | poly(rC) binding protein 2 | 0.0498818 |
| RPL13A | ribosomal protein L13a | 0.0498396 |
| PUM1 | pumilio RNA-binding family member 1 | 0.049537 |
| ZNF292 | zinc finger protein 292 | 0.0491857 |
| GOLGA4 | golgin A4 | 0.0476256 |
| LAMA4 | laminin, alpha 4 | 0.0471199 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0470924 |
| VCL | vinculin | 0.0469888 |
| SPAG9 | sperm associated antigen 9 | 0.0468735 |
| RREB1 | ras responsive element binding protein 1 | 0.0465856 |
| VMP1 | vacuole membrane protein 1 | 0.0465117 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0464386 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0461043 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0447603 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0445255 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0444447 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0438554 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0437669 |
| NUP58 | nucleoporin 58 | 0.0432885 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0423414 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0421912 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.042114 |
| GDF15 | growth differentiation factor 15 | 0.0419025 |
| SETD5 | SET domain containing 5 | 0.0417157 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0416215 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0415849 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0415075 |
| TRIM2 | tripartite motif containing 2 | 0.0413855 |
| RPL5 | ribosomal protein L5 | 0.041289 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0411873 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0403752 |
| SLMAP | sarcolemma associated protein | 0.0395947 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0390275 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0384472 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0383475 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0378502 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0374145 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0372903 |
| MED13 | mediator complex subunit 13 | 0.0372133 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0371855 |
| USP53 | ubiquitin specific peptidase 53 | 0.036916 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0364522 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.036429 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0358731 |
| DNM2 | dynamin 2 | 0.0354185 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0346392 |
| CTBP2 | C-terminal binding protein 2 | 0.0345735 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0345702 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0345097 |
| COG5 | component of oligomeric golgi complex 5 | 0.0345013 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0344045 |
| FHL2 | four and a half LIM domains 2 | 0.0338199 |
| RPS12 | ribosomal protein S12 | 0.0332888 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.033041 |
| RPS3 | ribosomal protein S3 | 0.0330253 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0328838 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0328002 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0326171 |
| MXD1 | MAX dimerization protein 1 | 0.0325068 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0324572 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0324356 |
| NCKAP1 | NCK-associated protein 1 | 0.0321531 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0320768 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0319107 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0318279 |
| TFG | TRK-fused gene | 0.0317466 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0311799 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0311544 |
| PTEN | phosphatase and tensin homolog | 0.0309497 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.213414 |
| TMSB10 | thymosin beta 10 | -0.172406 |
| PTMA | prothymosin, alpha | -0.151683 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.129715 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0959313 |
| RPL35A | ribosomal protein L35a | -0.0867267 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0865716 |
| AHNAK | AHNAK nucleoprotein | -0.0853373 |
| KRT18 | keratin 18, type I | -0.0792459 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0734043 |
| RPS19 | ribosomal protein S19 | -0.0718462 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0659101 |
| RPS24 | ribosomal protein S24 | -0.0497336 |
| CANX | calnexin | -0.0496123 |
| H1-0 | H1.0 linker histone | -0.0485029 |
| RPL34 | ribosomal protein L34 | -0.0470065 |
| ACTG1 | actin gamma 1 | -0.0459999 |
| KRT8 | keratin 8, type II | -0.0411123 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0378938 |
| RPS14 | ribosomal protein S14 | -0.0342781 |
| POTEF | POTE ankyrin domain family, member F | -0.0333481 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0324836 |
| RPL23 | ribosomal protein L23 | -0.0319941 |
| DSPP | dentin sialophosphoprotein | -0.0316085 |
| MUC17 | mucin 17, cell surface associated | -0.0314978 |
| YBX1 | Y box binding protein 1 | -0.0313677 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0297346 |
| AGR2 | anterior gradient 2 | -0.0292534 |
| S100A6 | S100 calcium binding protein A6 | -0.0289448 |
| RPL12 | ribosomal protein L12 | -0.0288087 |
| TPM4 | tropomyosin 4 | -0.0281184 |
| MT2A | metallothionein 2A | -0.0280979 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0268565 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0268535 |
| TUBA1B | tubulin, alpha 1b | -0.0268126 |
| TFF1 | trefoil factor 1 | -0.026351 |
| GOLGB1 | golgin B1 | -0.0258732 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0256677 |
| RPLP0 | ribosomal protein, large, P0 | -0.0254854 |
| VIM | vimentin | -0.0250515 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0250152 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0244792 |
| CENPF | centromere protein F, 350/400kDa | -0.0244149 |
| PGK1 | phosphoglycerate kinase 1 | -0.0236758 |
| FOSL1 | FOS-like antigen 1 | -0.0236517 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0231953 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0229454 |
| RPL4 | ribosomal protein L4 | -0.0220356 |
| IER3 | immediate early response 3 | -0.0215421 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0212616 |
| RPS6 | ribosomal protein S6 | -0.0210647 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0203979 |
| RPL14 | ribosomal protein L14 | -0.0199511 |
| FHIT | fragile histidine triad | -0.0197724 |
| ASPH | aspartate beta-hydroxylase | -0.0195186 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0191829 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0191369 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0189075 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.018694 |
| PKM | pyruvate kinase, muscle | -0.0182448 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0180971 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.017914 |
| CALB1 | calbindin 1, 28kDa | -0.017734 |
| HMGB1 | high mobility group box 1 | -0.0176667 |
| DSG2 | desmoglein 2 | -0.0174376 |
| NRN1 | neuritin 1 | -0.0173154 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | -0.0172936 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0172429 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0170434 |
| KLK10 | kallikrein-related peptidase 10 | -0.0170326 |
| ENO1 | enolase 1, (alpha) | -0.0170173 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0168749 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0166778 |
| RPS25 | ribosomal protein S25 | -0.0166363 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0164995 |
| FN1 | fibronectin 1 | -0.0161099 |
| RRBP1 | ribosome binding protein 1 | -0.016001 |
| RPL35 | ribosomal protein L35 | -0.0159877 |
| TUBB | tubulin, beta class I | -0.0157515 |
| RPL19 | ribosomal protein L19 | -0.0157431 |
| RPS23 | ribosomal protein S23 | -0.0155734 |
| UBB | ubiquitin B | -0.0155166 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0154814 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0154477 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0154385 |
| MT1X | metallothionein 1X | -0.0153418 |
| NPSR1 | neuropeptide S receptor 1 | -0.0153389 |
| RPS17 | ribosomal protein S17 | -0.0151788 |
| RPL3 | ribosomal protein L3 | -0.015071 |
| PERP | PERP, TP53 apoptosis effector | -0.0147715 |
| RPS4X | ribosomal protein S4, X-linked | -0.0146868 |
| RPL21 | ribosomal protein L21 | -0.0146521 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0145842 |
| HLA-A | major histocompatibility complex, class I, A | -0.0145748 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0145392 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0144969 |
| RAD51B | RAD51 paralog B | -0.0144028 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.0143656 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0142234 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0141855 |
