| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Captopril_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.208254 |
| SPAG9 | sperm associated antigen 9 | 0.123154 |
| PTMA | prothymosin, alpha | 0.0883717 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0858926 |
| CAPRIN2 | caprin family member 2 | 0.0801327 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0660415 |
| EREG | epiregulin | 0.0651808 |
| NUP58 | nucleoporin 58 | 0.058841 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0585633 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0554433 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0552718 |
| KLF6 | Kruppel-like factor 6 | 0.0537565 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0537278 |
| TMEM41B | transmembrane protein 41B | 0.0522513 |
| ARRDC3 | arrestin domain containing 3 | 0.0511276 |
| PUM2 | pumilio RNA-binding family member 2 | 0.050365 |
| RPS12 | ribosomal protein S12 | 0.0486152 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0480645 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0477907 |
| RPL26 | ribosomal protein L26 | 0.0469766 |
| OGA | O-GlcNAcase | 0.0468293 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0463552 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0458437 |
| ATP13A3 | ATPase type 13A3 | 0.0453642 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0450932 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0443652 |
| TOP1 | topoisomerase (DNA) I | 0.0435199 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0434252 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0432682 |
| RPL5 | ribosomal protein L5 | 0.0426783 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0425824 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.04202 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0396065 |
| CDC73 | cell division cycle 73 | 0.0395325 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0394473 |
| RPS8 | ribosomal protein S8 | 0.0391569 |
| ETNK1 | ethanolamine kinase 1 | 0.0376607 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0375029 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.035879 |
| XPO1 | exportin 1 | 0.0348463 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0347555 |
| SBF2 | SET binding factor 2 | 0.0346726 |
| NCKAP1 | NCK-associated protein 1 | 0.034397 |
| ZNF292 | zinc finger protein 292 | 0.0337273 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0336238 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0333148 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0332945 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0329652 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0323413 |
| RASA2 | RAS p21 protein activator 2 | 0.0323399 |
| QKI | QKI, KH domain containing, RNA binding | 0.0314459 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0308453 |
| JMJD1C | jumonji domain containing 1C | 0.0306711 |
| FOXJ3 | forkhead box J3 | 0.0306622 |
| VCL | vinculin | 0.0303649 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0303385 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0297121 |
| RAI1 | retinoic acid induced 1 | 0.0293549 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0293372 |
| FAM13B | family with sequence similarity 13, member B | 0.0291264 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0290146 |
| WDR45B | WD repeat domain 45B | 0.0285672 |
| USP12 | ubiquitin specific peptidase 12 | 0.0284583 |
| SEPTIN2 | septin 2 | 0.0283513 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0282972 |
| SQSTM1 | sequestosome 1 | 0.0281262 |
| DENND5A | DENN/MADD domain containing 5A | 0.0278285 |
| FNIP1 | folliculin interacting protein 1 | 0.0275578 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0274619 |
| RNF149 | ring finger protein 149 | 0.0272722 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0270734 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0265511 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0264306 |
| YME1L1 | YME1-like 1 ATPase | 0.0263838 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0262838 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0261853 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0260739 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0260337 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0259533 |
| ABI1 | abl-interactor 1 | 0.0258751 |
| MORC3 | MORC family CW-type zinc finger 3 | 0.0257907 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0255581 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0252663 |
| MEMO1 | mediator of cell motility 1 | 0.0252344 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0251621 |
| KIF1B | kinesin family member 1B | 0.0250613 |
| WDR43 | WD repeat domain 43 | 0.0250102 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0246807 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0246013 |
| CEP95 | centrosomal protein 95kDa | 0.024476 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0244493 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0244341 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0243964 |
| RBM39 | RNA binding motif protein 39 | 0.0243014 |
| NEK7 | NIMA-related kinase 7 | 0.0242961 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0242755 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0242424 |
| PYGB | phosphorylase, glycogen; brain | 0.0241172 |
| RAB10 | RAB10, member RAS oncogene family | 0.0239127 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0238951 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.196838 |
| MT2A | metallothionein 2A | -0.163399 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.134766 |
| TP63 | tumor protein p63 | -0.131987 |
| POTEF | POTE ankyrin domain family, member F | -0.111704 |
| VIM | vimentin | -0.107198 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0931573 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0914788 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0828129 |
| CD44 | CD44 molecule (Indian blood group) | -0.0798782 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.075429 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0753787 |
| MT1X | metallothionein 1X | -0.0700763 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0697183 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0696227 |
| FTL | ferritin, light polypeptide | -0.0669114 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0661763 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0659447 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0656824 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0653247 |
| ACTG1 | actin gamma 1 | -0.0639188 |
| CADM2 | cell adhesion molecule 2 | -0.0629067 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0626416 |
| RPS19 | ribosomal protein S19 | -0.061886 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0603003 |
| CANX | calnexin | -0.0602133 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0602055 |
| RNF213 | ring finger protein 213 | -0.0569985 |
| COL5A2 | collagen, type V, alpha 2 | -0.0519194 |
| RPL35A | ribosomal protein L35a | -0.0489132 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0469363 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0439025 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0435928 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0432949 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0432659 |
| RAD51B | RAD51 paralog B | -0.0432593 |
| AHNAK | AHNAK nucleoprotein | -0.0431296 |
| SP100 | SP100 nuclear antigen | -0.042905 |
| EXOC4 | exocyst complex component 4 | -0.0428991 |
| EHBP1 | EH domain binding protein 1 | -0.0426795 |
| ENO1 | enolase 1, (alpha) | -0.0416603 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.041212 |
| EGR1 | early growth response 1 | -0.0409524 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0407404 |
| DNER | delta/notch-like EGF repeat containing | -0.0398343 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0397027 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0392349 |
| PKM | pyruvate kinase, muscle | -0.037082 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0368765 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0368551 |
| EPHA4 | EPH receptor A4 | -0.0368546 |
| TNS3 | tensin 3 | -0.0367686 |
| CMIP | c-Maf inducing protein | -0.0363669 |
| HLA-B | major histocompatibility complex, class I, B | -0.0362974 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0357543 |
| CDK6 | cyclin-dependent kinase 6 | -0.0355693 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0354531 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0351565 |
| TAPBP | TAP binding protein (tapasin) | -0.0349569 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0347572 |
| PGK1 | phosphoglycerate kinase 1 | -0.0346142 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0335934 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0333757 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.033045 |
| ATN1 | atrophin 1 | -0.032725 |
| WDR27 | WD repeat domain 27 | -0.0324015 |
| BPTF | bromodomain PHD finger transcription factor | -0.0316837 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0316336 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | -0.0316004 |
| PCBP2 | poly(rC) binding protein 2 | -0.0309162 |
| HLA-A | major histocompatibility complex, class I, A | -0.0305643 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0303551 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0300586 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0296364 |
| ITGB4 | integrin, beta 4 | -0.0295141 |
| BRD4 | bromodomain containing 4 | -0.0289547 |
| HDLBP | high density lipoprotein binding protein | -0.0286565 |
| SYT1 | synaptotagmin I | -0.0281545 |
| SETX | senataxin | -0.0281376 |
| PODXL | podocalyxin-like | -0.0279095 |
| ACTN4 | actinin, alpha 4 | -0.0277816 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0277147 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0276162 |
| LOXL2 | lysyl oxidase-like 2 | -0.0275056 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0274067 |
| SMIM44 | small integral membrane protein 44 | -0.0272386 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0268333 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0266778 |
| JUN | jun proto-oncogene | -0.0264498 |
| ECE1 | endothelin converting enzyme 1 | -0.0255957 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0251954 |
| NSD1 | nuclear receptor binding SET domain protein 1 | -0.0251796 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0250821 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0249719 |
| H1-0 | H1.0 linker histone | -0.0247984 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0246748 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0243329 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0240435 |
| DPH6 | diphthamine biosynthesis 6 | -0.0240377 |
| APP | amyloid beta (A4) precursor protein | -0.0239349 |
