| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Captopril_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.306029 |
| FAM13A | family with sequence similarity 13, member A | 0.11658 |
| SPAG9 | sperm associated antigen 9 | 0.0945244 |
| TMEM165 | transmembrane protein 165 | 0.0823866 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0803169 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0799296 |
| NGLY1 | N-glycanase 1 | 0.0723633 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0722437 |
| NDRG1 | N-myc downstream regulated 1 | 0.0673612 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0648305 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0619698 |
| RNF145 | ring finger protein 145 | 0.0610883 |
| RAB7A | RAB7A, member RAS oncogene family | 0.060983 |
| ARRDC3 | arrestin domain containing 3 | 0.0600226 |
| SEPTIN2 | septin 2 | 0.0580754 |
| ATP13A3 | ATPase type 13A3 | 0.0574032 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0524569 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0511417 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0483721 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0482311 |
| ANXA5 | annexin A5 | 0.0480975 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0461581 |
| RPL5 | ribosomal protein L5 | 0.0455262 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0454522 |
| TOP1 | topoisomerase (DNA) I | 0.0451117 |
| ANXA2 | annexin A2 | 0.0446829 |
| SRP54 | signal recognition particle 54kDa | 0.0442705 |
| UVRAG | UV radiation resistance associated | 0.0434247 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.043194 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0424242 |
| RUNX1 | runt-related transcription factor 1 | 0.0416323 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0409164 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0403464 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0394228 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0379081 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0377335 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0371859 |
| WASF2 | WAS protein family, member 2 | 0.0371209 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0363433 |
| RPS3 | ribosomal protein S3 | 0.0362467 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0362262 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0361039 |
| SLMAP | sarcolemma associated protein | 0.0358294 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0350879 |
| SETD5 | SET domain containing 5 | 0.0348726 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0344756 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0343538 |
| PDE8A | phosphodiesterase 8A | 0.0339559 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0339123 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0338953 |
| HELZ | helicase with zinc finger | 0.0333675 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0330389 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0330088 |
| TPD52 | tumor protein D52 | 0.0328122 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0318488 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0314514 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0311008 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0307842 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0306088 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0306017 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0305152 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0302192 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0302189 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0300091 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0297033 |
| ABLIM1 | actin binding LIM protein 1 | 0.0296842 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0295571 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.029111 |
| MED13L | mediator complex subunit 13-like | 0.0282515 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0282332 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0277263 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0276313 |
| NUP58 | nucleoporin 58 | 0.0276279 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0274859 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0273557 |
| HMGA1 | high mobility group AT-hook 1 | 0.0273383 |
| OGA | O-GlcNAcase | 0.0272886 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.026795 |
| MT2A | metallothionein 2A | 0.0267181 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0266816 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0266805 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0266793 |
| NCKAP1 | NCK-associated protein 1 | 0.0258674 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0258353 |
| FTL | ferritin, light polypeptide | 0.0257895 |
| ZNF292 | zinc finger protein 292 | 0.0257759 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0256627 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0255301 |
| ADGRG7 | adhesion G protein-coupled receptor G7 | 0.0254826 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0252956 |
| USP3 | ubiquitin specific peptidase 3 | 0.0249703 |
| PCBP2 | poly(rC) binding protein 2 | 0.024562 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0244128 |
| FAM193A | family with sequence similarity 193, member A | 0.0243475 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0241094 |
| FNIP1 | folliculin interacting protein 1 | 0.0240488 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0240211 |
| RPS8 | ribosomal protein S8 | 0.0238366 |
| FA2H | fatty acid 2-hydroxylase | 0.0238257 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0235306 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.171339 |
| TXNRD1 | thioredoxin reductase 1 | -0.15662 |
| TMSB10 | thymosin beta 10 | -0.152721 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.130834 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.088146 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0766575 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0749428 |
| H1-0 | H1.0 linker histone | -0.0687514 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0652456 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0618554 |
| CANX | calnexin | -0.0617005 |
| AHNAK | AHNAK nucleoprotein | -0.0581866 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.057485 |
| LAMC2 | laminin, gamma 2 | -0.0552658 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0545434 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0531879 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0527925 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0498849 |
| ACTG1 | actin gamma 1 | -0.0474556 |
| LMO7 | LIM domain 7 | -0.045347 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0447072 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0445387 |
| KRT18 | keratin 18, type I | -0.0443433 |
| KRT7 | keratin 7, type II | -0.0420141 |
| GOLGB1 | golgin B1 | -0.0402732 |
| GRAMD1B | GRAM domain containing 1B | -0.0394597 |
| LDHA | lactate dehydrogenase A | -0.0390781 |
| PLEC | plectin | -0.0387704 |
| PKM | pyruvate kinase, muscle | -0.0386684 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0386367 |
| SEC61G | Sec61 gamma subunit | -0.0383156 |
| MYOF | myoferlin | -0.0364934 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0363294 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0362644 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0358183 |
| CES1 | carboxylesterase 1 | -0.0352157 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0343287 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.033862 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0317506 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0314684 |
| LAMB3 | laminin, beta 3 | -0.0311374 |
| SMAD3 | SMAD family member 3 | -0.0308844 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0306635 |
| CST3 | cystatin C | -0.0303882 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0296198 |
| RNF213 | ring finger protein 213 | -0.0295332 |
| PGK1 | phosphoglycerate kinase 1 | -0.0291081 |
| EFNA5 | ephrin-A5 | -0.0289207 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0288107 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0283435 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0274747 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0270976 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.026139 |
| SDC4 | syndecan 4 | -0.026112 |
| APP | amyloid beta (A4) precursor protein | -0.0259769 |
| POTEF | POTE ankyrin domain family, member F | -0.0256181 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0256123 |
| ARF1 | ADP-ribosylation factor 1 | -0.0254528 |
| CCND1 | cyclin D1 | -0.0252654 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0250581 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0249574 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0247929 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0246798 |
| RPL4 | ribosomal protein L4 | -0.0245637 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0245504 |
| RPL35A | ribosomal protein L35a | -0.0244807 |
| DSPP | dentin sialophosphoprotein | -0.0242983 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0238872 |
| CLTC | clathrin, heavy chain (Hc) | -0.0237022 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0234397 |
| ENO1 | enolase 1, (alpha) | -0.0231875 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0231253 |
| SP100 | SP100 nuclear antigen | -0.0230797 |
| KRT8 | keratin 8, type II | -0.0230734 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0228131 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0226957 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0222642 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0222514 |
| SMYD3 | SET and MYND domain containing 3 | -0.0218487 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0216519 |
| UBC | ubiquitin C | -0.021183 |
| RPL3 | ribosomal protein L3 | -0.0211279 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0211205 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0209297 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0208543 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0208259 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0203869 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.020342 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0203212 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0200724 |
| CTSL | cathepsin L | -0.0199196 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.019913 |
| MT1X | metallothionein 1X | -0.0197834 |
| WDR1 | WD repeat domain 1 | -0.01974 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.019621 |
| MCL1 | myeloid cell leukemia 1 | -0.0195996 |
| GM2A | GM2 ganglioside activator | -0.019353 |
| RPS2 | ribosomal protein S2 | -0.0193325 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0190706 |
| IFI44 | interferon-induced protein 44 | -0.018934 |
