| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Captopril_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.155847 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.113531 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.110569 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0781568 |
| VIM | vimentin | 0.0627656 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0591625 |
| OGA | O-GlcNAcase | 0.0536852 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0487248 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0486848 |
| FAM13A | family with sequence similarity 13, member A | 0.0475614 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0474123 |
| ATP13A3 | ATPase type 13A3 | 0.0462864 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0457967 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.042254 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0420462 |
| USP34 | ubiquitin specific peptidase 34 | 0.0418871 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0411025 |
| PRELID2 | PRELI domain containing 2 | 0.0403152 |
| MT2A | metallothionein 2A | 0.0394074 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0391454 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0385436 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0380641 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0380101 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0365906 |
| CDCP1 | CUB domain containing protein 1 | 0.0361856 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0361598 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0352234 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0349427 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0345788 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0345267 |
| RPS12 | ribosomal protein S12 | 0.0343625 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0337791 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.033734 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0312937 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0311534 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0311284 |
| EFNA5 | ephrin-A5 | 0.031112 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0308643 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0303016 |
| NGLY1 | N-glycanase 1 | 0.0295531 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0295311 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0293323 |
| RNF149 | ring finger protein 149 | 0.0290692 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0290531 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0288719 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0282137 |
| PTMA | prothymosin, alpha | 0.0273971 |
| RASA2 | RAS p21 protein activator 2 | 0.0271816 |
| KLF6 | Kruppel-like factor 6 | 0.0270323 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0269741 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0268779 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0268503 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0267933 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0266246 |
| ANGPTL4 | angiopoietin-like 4 | 0.0263621 |
| RPLP2 | ribosomal protein, large, P2 | 0.0262969 |
| RPS3 | ribosomal protein S3 | 0.0262118 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0260732 |
| YEATS2 | YEATS domain containing 2 | 0.0259967 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.025822 |
| SBF2 | SET binding factor 2 | 0.025692 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0256716 |
| RPL23 | ribosomal protein L23 | 0.0253372 |
| ANXA5 | annexin A5 | 0.0252261 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0252196 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0250499 |
| FLNB | filamin B, beta | 0.0247942 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0246563 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0244159 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0243984 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0243981 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0243472 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0241557 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0239273 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.02382 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0238125 |
| RAI1 | retinoic acid induced 1 | 0.0237773 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0237694 |
| IER3 | immediate early response 3 | 0.0234821 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0233736 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.023333 |
| SEPTIN2 | septin 2 | 0.0233079 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0232649 |
| SERINC1 | serine incorporator 1 | 0.0231843 |
| RIOK3 | RIO kinase 3 | 0.0231671 |
| RNF145 | ring finger protein 145 | 0.0231185 |
| CAB39 | calcium binding protein 39 | 0.0230486 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.02289 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.022694 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0225215 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0224612 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0224442 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0224281 |
| TSPAN5 | tetraspanin 5 | 0.0223918 |
| FNBP1 | formin binding protein 1 | 0.0223454 |
| RPS8 | ribosomal protein S8 | 0.0222563 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0221707 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0221615 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0215661 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0215156 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.291545 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.196453 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.145007 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.130002 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.115034 |
| FN1 | fibronectin 1 | -0.107656 |
| NDRG1 | N-myc downstream regulated 1 | -0.0983352 |
| EGR1 | early growth response 1 | -0.0846463 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0682347 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0673465 |
| LOX | lysyl oxidase | -0.0619469 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0610327 |
| TMSB10 | thymosin beta 10 | -0.0607845 |
| MAP1B | microtubule-associated protein 1B | -0.0542851 |
| CD44 | CD44 molecule (Indian blood group) | -0.0535676 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0532522 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0509076 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0508399 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0486455 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0485316 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0473434 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0471301 |
| PCBP2 | poly(rC) binding protein 2 | -0.0451685 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0448791 |
| ANKRD28 | ankyrin repeat domain 28 | -0.043905 |
| YBX1 | Y box binding protein 1 | -0.0421299 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0416253 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0412053 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0385481 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0383285 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0372954 |
| POTEF | POTE ankyrin domain family, member F | -0.0361533 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0354012 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0350131 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0337428 |
| AADAC | arylacetamide deacetylase | -0.0336565 |
| ARF4 | ADP-ribosylation factor 4 | -0.033421 |
| PKM | pyruvate kinase, muscle | -0.0334094 |
| GLCCI1 | glucocorticoid induced 1 | -0.0331247 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0326449 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0324895 |
| NTN4 | netrin 4 | -0.0324393 |
| NRG1 | neuregulin 1 | -0.0315907 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0302075 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.030089 |
| HDLBP | high density lipoprotein binding protein | -0.0295295 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0290512 |
| JUN | jun proto-oncogene | -0.0289211 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0285848 |
| H1-0 | H1.0 linker histone | -0.0285336 |
| MCL1 | myeloid cell leukemia 1 | -0.0281996 |
| TGFB1 | transforming growth factor, beta 1 | -0.0280239 |
| PFN1 | profilin 1 | -0.0272361 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0259857 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0257753 |
| PRR16 | proline rich 16 | -0.0257702 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0250913 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0248582 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0247385 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0246379 |
| ATF7 | activating transcription factor 7 | -0.0246142 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0244429 |
| TAPBP | TAP binding protein (tapasin) | -0.0242865 |
| FTL | ferritin, light polypeptide | -0.0242519 |
| COPA | coatomer protein complex, subunit alpha | -0.0242273 |
| LDHA | lactate dehydrogenase A | -0.0241562 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0240397 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0237322 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0236516 |
| INTS6 | integrator complex subunit 6 | -0.0229567 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0228134 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0227263 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0227236 |
| EZR | ezrin | -0.0226213 |
| GPATCH2L | G patch domain containing 2-like | -0.022291 |
| AHNAK | AHNAK nucleoprotein | -0.021833 |
| NOTCH2 | notch 2 | -0.021774 |
| GPC6 | glypican 6 | -0.0216921 |
| CANX | calnexin | -0.0216246 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.021582 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0214437 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0213729 |
| VCL | vinculin | -0.0213423 |
| NLK | nemo-like kinase | -0.0212624 |
| MBD6 | methyl-CpG binding domain protein 6 | -0.0211161 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0210164 |
| WASF2 | WAS protein family, member 2 | -0.0210122 |
| TNNC1 | troponin C type 1 (slow) | -0.0209558 |
| CDH13 | cadherin 13 | -0.0209342 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0209332 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0207885 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0205789 |
| GLIS3 | GLIS family zinc finger 3 | -0.0203364 |
| TMEM263 | transmembrane protein 263 | -0.0203106 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0203102 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.020041 |
| RPL28 | ribosomal protein L28 | -0.0199878 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0197957 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0195049 |
| VRK2 | vaccinia related kinase 2 | -0.0194911 |
