| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Captopril_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.144505 |
| VIM | vimentin | 0.118006 |
| TXNRD1 | thioredoxin reductase 1 | 0.0995058 |
| PTMA | prothymosin, alpha | 0.0911738 |
| IGF2 | insulin-like growth factor 2 | 0.0682946 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0660357 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0584637 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0563954 |
| TPM3 | tropomyosin 3 | 0.0559332 |
| TPM4 | tropomyosin 4 | 0.0532889 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0530733 |
| HDAC9 | histone deacetylase 9 | 0.0504613 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.050262 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0501585 |
| YME1L1 | YME1-like 1 ATPase | 0.0498209 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0492961 |
| WDR43 | WD repeat domain 43 | 0.049031 |
| ERBIN | erbb2 interacting protein | 0.0470079 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0455942 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0438945 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0437594 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0433849 |
| S100A6 | S100 calcium binding protein A6 | 0.0429281 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0424716 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0409212 |
| CAVIN1 | caveolae associated protein 1 | 0.0395013 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0392735 |
| CHN1 | chimerin 1 | 0.0391795 |
| MTMR3 | myotubularin related protein 3 | 0.0391456 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0386103 |
| PLS3 | plastin 3 | 0.0382886 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0381484 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0374596 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0373211 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0372505 |
| FNBP1L | formin binding protein 1-like | 0.0372349 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0366459 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0364447 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0354473 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0354102 |
| USP3 | ubiquitin specific peptidase 3 | 0.035283 |
| ANXA5 | annexin A5 | 0.0352694 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0345235 |
| RBM8A | RNA binding motif protein 8A | 0.0340348 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0337648 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0335735 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0333235 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0331625 |
| SRGN | serglycin | 0.0328572 |
| MYOF | myoferlin | 0.0328475 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.032773 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0323449 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0317196 |
| HMGA1 | high mobility group AT-hook 1 | 0.0316842 |
| SFTPA2 | surfactant protein A2 | 0.0313848 |
| RPS7 | ribosomal protein S7 | 0.0311558 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.031054 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0307641 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0307333 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.0305938 |
| SETD5 | SET domain containing 5 | 0.0305672 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0305417 |
| TMEM123 | transmembrane protein 123 | 0.0303345 |
| ZNF292 | zinc finger protein 292 | 0.0299712 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0298066 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0294173 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0293363 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0289614 |
| RPL5 | ribosomal protein L5 | 0.0286351 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0281669 |
| RBM25 | RNA binding motif protein 25 | 0.0279126 |
| RTN4 | reticulon 4 | 0.0278924 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0278046 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0277137 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0276055 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0276029 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0274707 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0274327 |
| PFDN2 | prefoldin subunit 2 | 0.0271526 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0271475 |
| GTPBP4 | GTP binding protein 4 | 0.0268466 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0267659 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0266585 |
| HDGF | hepatoma-derived growth factor | 0.0263425 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0258144 |
| SLMAP | sarcolemma associated protein | 0.0256561 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.025628 |
| ANXA2 | annexin A2 | 0.0255191 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0255188 |
| BTBD7 | BTB (POZ) domain containing 7 | 0.0254963 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0253601 |
| CANX | calnexin | 0.0252867 |
| ITGAV | integrin, alpha V | 0.0252456 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0252087 |
| ECT2 | epithelial cell transforming 2 | 0.0250804 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.025058 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0249835 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0249125 |
| ANXA1 | annexin A1 | 0.0248409 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0246003 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.279085 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.192871 |
| TMSB10 | thymosin beta 10 | -0.184469 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.127149 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.110463 |
| FTL | ferritin, light polypeptide | -0.0989072 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0940823 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0826206 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0670437 |
| RPS19 | ribosomal protein S19 | -0.0647205 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0613139 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.059943 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.057219 |
| RPLP1 | ribosomal protein, large, P1 | -0.056013 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0530223 |
| BRD2 | bromodomain containing 2 | -0.0511951 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0505165 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0485709 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0483235 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0472063 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0447877 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0444562 |
| RPS20 | ribosomal protein S20 | -0.0440638 |
| KYNU | kynureninase | -0.0431341 |
| EGR1 | early growth response 1 | -0.0407844 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0405397 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0399865 |
| FGB | fibrinogen beta chain | -0.0391818 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0373628 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.037233 |
| RPL36 | ribosomal protein L36 | -0.0361705 |
| RPL19 | ribosomal protein L19 | -0.0360631 |
| EGFR | epidermal growth factor receptor | -0.0355949 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0318312 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0315122 |
| NNMT | nicotinamide N-methyltransferase | -0.0315025 |
| HLA-B | major histocompatibility complex, class I, B | -0.0313554 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0311744 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0309916 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0309121 |
| ATXN1 | ataxin 1 | -0.0306836 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0304872 |
| RPS16 | ribosomal protein S16 | -0.0291187 |
| AHNAK | AHNAK nucleoprotein | -0.0285984 |
| CENPF | centromere protein F, 350/400kDa | -0.0282901 |
| ZNF638 | zinc finger protein 638 | -0.0281243 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0276693 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.026721 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0264378 |
| GLIS3 | GLIS family zinc finger 3 | -0.025972 |
| CD44 | CD44 molecule (Indian blood group) | -0.0259029 |
| LAMA5 | laminin, alpha 5 | -0.0258647 |
| WWOX | WW domain containing oxidoreductase | -0.0255742 |
| HLA-A | major histocompatibility complex, class I, A | -0.0255005 |
| GOLGB1 | golgin B1 | -0.0254381 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0249955 |
| CMIP | c-Maf inducing protein | -0.0241455 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0240729 |
| RPL35A | ribosomal protein L35a | -0.024051 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0240465 |
| DSCAM | Down syndrome cell adhesion molecule | -0.023969 |
| INTS6 | integrator complex subunit 6 | -0.0239567 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.023431 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0229724 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0229643 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0228354 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.022768 |
| AGO2 | argonaute RISC catalytic component 2 | -0.022708 |
| RPS5 | ribosomal protein S5 | -0.0226761 |
| TRIP11 | thyroid hormone receptor interactor 11 | -0.0225135 |
| NDRG1 | N-myc downstream regulated 1 | -0.0224903 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0224248 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0218635 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0218213 |
| TNS3 | tensin 3 | -0.0218157 |
| RPS12 | ribosomal protein S12 | -0.021741 |
| GPHN | gephyrin | -0.0216185 |
| RPS29 | ribosomal protein S29 | -0.0213509 |
| RPL28 | ribosomal protein L28 | -0.0213041 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0210626 |
| CDK13 | cyclin-dependent kinase 13 | -0.020917 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0208879 |
| EXOC6B | exocyst complex component 6B | -0.0208279 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.020722 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.020702 |
| CREBBP | CREB binding protein | -0.0205093 |
| MCL1 | myeloid cell leukemia 1 | -0.0199207 |
| FOXO3 | forkhead box O3 | -0.0198478 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0196661 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0195496 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0195278 |
| TPM1 | tropomyosin 1 (alpha) | -0.0194787 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0194506 |
| NBEAL1 | neurobeachin-like 1 | -0.0194295 |
| SRBD1 | S1 RNA binding domain 1 | -0.0193912 |
| ATF4 | activating transcription factor 4 | -0.0192136 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.019174 |
| ATG7 | autophagy related 7 | -0.0190308 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0189838 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | -0.018898 |
