| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Captopril_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.217074 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.162341 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.141399 |
| DTNA | dystrobrevin, alpha | 0.119199 |
| DSCAM | Down syndrome cell adhesion molecule | 0.117514 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.105493 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0878191 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0829173 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0799598 |
| KRT17 | keratin 17, type I | 0.0773338 |
| FTL | ferritin, light polypeptide | 0.0765016 |
| ZNF292 | zinc finger protein 292 | 0.0760993 |
| PUM2 | pumilio RNA-binding family member 2 | 0.070268 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.068205 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0676051 |
| S100A9 | S100 calcium binding protein A9 | 0.067438 |
| KYNU | kynureninase | 0.0667508 |
| FAM13A | family with sequence similarity 13, member A | 0.0655422 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0634851 |
| PTMA | prothymosin, alpha | 0.061711 |
| ANXA2 | annexin A2 | 0.0615332 |
| MT2A | metallothionein 2A | 0.0608887 |
| RTN4 | reticulon 4 | 0.0607453 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0606166 |
| S100P | S100 calcium binding protein P | 0.0605008 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0603686 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0595611 |
| RPS19 | ribosomal protein S19 | 0.0591034 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0583914 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0578081 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0558389 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0532978 |
| ANXA1 | annexin A1 | 0.0532723 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.053158 |
| NCKAP1 | NCK-associated protein 1 | 0.0526608 |
| WDR45B | WD repeat domain 45B | 0.0520525 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0515054 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0509075 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0502348 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0489497 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.048788 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0482565 |
| GOLGA4 | golgin A4 | 0.0478649 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0478484 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0474724 |
| FLNB | filamin B, beta | 0.04739 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0467924 |
| PTK2 | protein tyrosine kinase 2 | 0.0463032 |
| UBC | ubiquitin C | 0.0458984 |
| ARRDC3 | arrestin domain containing 3 | 0.0457327 |
| KIF5B | kinesin family member 5B | 0.0455728 |
| TMEM165 | transmembrane protein 165 | 0.04437 |
| MEF2A | myocyte enhancer factor 2A | 0.0442152 |
| CDCP1 | CUB domain containing protein 1 | 0.0441985 |
| RNF149 | ring finger protein 149 | 0.0441126 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0433701 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0431093 |
| NGLY1 | N-glycanase 1 | 0.0430966 |
| SDC4 | syndecan 4 | 0.0430657 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0421176 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0411857 |
| RYBP | RING1 and YY1 binding protein | 0.0409816 |
| SPAG9 | sperm associated antigen 9 | 0.0409448 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0403212 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0399775 |
| RUNX1 | runt-related transcription factor 1 | 0.0394595 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0390481 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0384174 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.038188 |
| QKI | QKI, KH domain containing, RNA binding | 0.0380082 |
| DSTN | destrin (actin depolymerizing factor) | 0.0379208 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0379197 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0379067 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0377306 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0375913 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0372723 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0371269 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0366693 |
| RPS12 | ribosomal protein S12 | 0.0366228 |
| WDR26 | WD repeat domain 26 | 0.0365491 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0364644 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0362902 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0360439 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0359932 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0358359 |
| ZNF207 | zinc finger protein 207 | 0.0353079 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0352603 |
| LAMB3 | laminin, beta 3 | 0.0351276 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0347342 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0342197 |
| HELZ | helicase with zinc finger | 0.0341632 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0340937 |
| RNF145 | ring finger protein 145 | 0.0334693 |
| RLF | rearranged L-myc fusion | 0.0333713 |
| FNBP1L | formin binding protein 1-like | 0.0332681 |
| AFTPH | aftiphilin | 0.0329122 |
| RPL23 | ribosomal protein L23 | 0.0327735 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0326087 |
| RPS3 | ribosomal protein S3 | 0.0325498 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0324523 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.135652 |
| MYO1E | myosin IE | -0.131345 |
| MUC16 | mucin 16, cell surface associated | -0.130602 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.105215 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.10253 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0971964 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0871125 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0843861 |
| FN1 | fibronectin 1 | -0.0786678 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0785324 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0700081 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0698629 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0696406 |
| AK1 | adenylate kinase 1 | -0.0645347 |
| SVIL | supervillin | -0.0644476 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.064299 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0638853 |
| SLTM | SAFB-like, transcription modulator | -0.063436 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0633812 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0624324 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0623567 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0621031 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0620901 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0618247 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0611935 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0610996 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0610942 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0599333 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.058265 |
| CD44 | CD44 molecule (Indian blood group) | -0.0576163 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0570598 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0567486 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0555319 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0547424 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0545843 |
| OSMR | oncostatin M receptor | -0.0543007 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0528831 |
| RBM47 | RNA binding motif protein 47 | -0.0525165 |
| DST | dystonin | -0.0518937 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0508584 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0505974 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0500828 |
| SRPK2 | SRSF protein kinase 2 | -0.0500058 |
| JUP | junction plakoglobin | -0.0493603 |
| RNF213 | ring finger protein 213 | -0.0492735 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0488352 |
| TUFT1 | tuftelin 1 | -0.0488039 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0477806 |
| EHBP1 | EH domain binding protein 1 | -0.0470455 |
| ACTG1 | actin gamma 1 | -0.0469909 |
| GLIS3 | GLIS family zinc finger 3 | -0.0468608 |
| SMYD3 | SET and MYND domain containing 3 | -0.0464484 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0463767 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0463348 |
| INHBA | inhibin, beta A | -0.0461671 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0461029 |
| AHNAK | AHNAK nucleoprotein | -0.0448183 |
| ASPH | aspartate beta-hydroxylase | -0.0447309 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0443495 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0443407 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0439701 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0435126 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0428274 |
| MYO1B | myosin IB | -0.0428266 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.041473 |
| BPTF | bromodomain PHD finger transcription factor | -0.0412515 |
| RANBP2 | RAN binding protein 2 | -0.0407602 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0400371 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0393177 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.0392861 |
| NAV1 | neuron navigator 1 | -0.0389962 |
| TXNRD1 | thioredoxin reductase 1 | -0.0381776 |
| MYO5B | myosin VB | -0.0369918 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0369075 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0367393 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0365869 |
| MYO9A | myosin IXA | -0.0364091 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0363439 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0361737 |
| DENND5B | DENN/MADD domain containing 5B | -0.0359714 |
| CUX1 | cut-like homeobox 1 | -0.0356816 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0355291 |
| TPM4 | tropomyosin 4 | -0.035309 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0352364 |
| ANTXR2 | anthrax toxin receptor 2 | -0.035204 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.0351748 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0348636 |
| CADM2 | cell adhesion molecule 2 | -0.0346208 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0344104 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0342696 |
| MEIS1 | Meis homeobox 1 | -0.0339985 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0339047 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0338671 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0338367 |
| ERBIN | erbb2 interacting protein | -0.0336572 |
| RCOR1 | REST corepressor 1 | -0.0334869 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0334135 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0332102 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0327256 |
| GON4L | gon-4-like (C. elegans) | -0.0325915 |
