| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Captopril_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.141666 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.12734 |
| HMGA1 | high mobility group AT-hook 1 | 0.107191 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0994071 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.096981 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0913916 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0769467 |
| ANXA5 | annexin A5 | 0.0744034 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.071576 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0715278 |
| MT2A | metallothionein 2A | 0.0675894 |
| ASPH | aspartate beta-hydroxylase | 0.0668925 |
| ARRDC3 | arrestin domain containing 3 | 0.0639916 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0625935 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0597361 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0588536 |
| RNF145 | ring finger protein 145 | 0.0536551 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0534826 |
| MYO6 | myosin VI | 0.0513978 |
| NUP58 | nucleoporin 58 | 0.0499092 |
| SLMAP | sarcolemma associated protein | 0.0463619 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.044976 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0445031 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0445024 |
| AREG | amphiregulin | 0.0439946 |
| ZNF292 | zinc finger protein 292 | 0.0432049 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0422344 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0405844 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0397193 |
| SPAG9 | sperm associated antigen 9 | 0.038746 |
| NCKAP1 | NCK-associated protein 1 | 0.0381474 |
| RPS3 | ribosomal protein S3 | 0.0379927 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0379537 |
| RPL23 | ribosomal protein L23 | 0.0374578 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.037451 |
| NDRG1 | N-myc downstream regulated 1 | 0.0372735 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0367522 |
| ATP13A3 | ATPase type 13A3 | 0.0367505 |
| RPL5 | ribosomal protein L5 | 0.03616 |
| RPS12 | ribosomal protein S12 | 0.0351242 |
| ANXA1 | annexin A1 | 0.0343983 |
| UPP1 | uridine phosphorylase 1 | 0.0343944 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0343935 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0341139 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0324311 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0324301 |
| MSN | moesin | 0.0323238 |
| RPLP2 | ribosomal protein, large, P2 | 0.0320841 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0320705 |
| RPS8 | ribosomal protein S8 | 0.0320016 |
| GOLGA4 | golgin A4 | 0.0317405 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0314157 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0313664 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.030583 |
| CPNE8 | copine VIII | 0.0305644 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0299519 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0298338 |
| RPL9 | ribosomal protein L9 | 0.0296221 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0289797 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0289536 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0284503 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0281976 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0281949 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0277189 |
| RASA2 | RAS p21 protein activator 2 | 0.0272582 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0272426 |
| MXD1 | MAX dimerization protein 1 | 0.0269916 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0268893 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0265124 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0264609 |
| B2M | beta-2-microglobulin | 0.0263917 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0261581 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0257794 |
| CCNG2 | cyclin G2 | 0.025509 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0254555 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0253825 |
| CDC73 | cell division cycle 73 | 0.0252639 |
| RACK1 | receptor for activated C kinase 1 | 0.0251499 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0244284 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0241766 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0241177 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0240683 |
| TFG | TRK-fused gene | 0.0240599 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0239366 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0237205 |
| FERMT2 | fermitin family member 2 | 0.0235258 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.023519 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0233143 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0228191 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0226806 |
| SQSTM1 | sequestosome 1 | 0.0226508 |
| RUNX1 | runt-related transcription factor 1 | 0.0226459 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0224793 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0224624 |
| VMP1 | vacuole membrane protein 1 | 0.0223418 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.022163 |
| RPS13 | ribosomal protein S13 | 0.0218965 |
| RPL7 | ribosomal protein L7 | 0.0218564 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0217547 |
| TNPO1 | transportin 1 | 0.0217139 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.174055 |
| FN1 | fibronectin 1 | -0.171675 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.16601 |
| ACTG1 | actin gamma 1 | -0.163268 |
| POTEF | POTE ankyrin domain family, member F | -0.154031 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.115783 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0999264 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0923184 |
| AHNAK | AHNAK nucleoprotein | -0.0894636 |
| RPL35A | ribosomal protein L35a | -0.0734333 |
| CANX | calnexin | -0.0700091 |
| LMO7 | LIM domain 7 | -0.0637328 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0635335 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0525932 |
| PLEC | plectin | -0.0513846 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0501016 |
| MAP1B | microtubule-associated protein 1B | -0.0489899 |
| KRT7 | keratin 7, type II | -0.048077 |
| H1-0 | H1.0 linker histone | -0.0479516 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0476976 |
| GNAS | GNAS complex locus | -0.0476374 |
| TMSB4X | thymosin beta 4, X-linked | -0.0475753 |
| ARF1 | ADP-ribosylation factor 1 | -0.0460212 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0452551 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0435084 |
| FBXO32 | F-box protein 32 | -0.0416152 |
| DSPP | dentin sialophosphoprotein | -0.0416109 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0414982 |
| RRBP1 | ribosome binding protein 1 | -0.040828 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.040819 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.040415 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0386707 |
| GOLGB1 | golgin B1 | -0.0373862 |
| RPS19 | ribosomal protein S19 | -0.0350505 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.034811 |
| HLA-A | major histocompatibility complex, class I, A | -0.034585 |
| RNF213 | ring finger protein 213 | -0.0335562 |
| CD2AP | CD2-associated protein | -0.0333145 |
| RPL14 | ribosomal protein L14 | -0.0331461 |
| RPLP1 | ribosomal protein, large, P1 | -0.0321476 |
| TPM4 | tropomyosin 4 | -0.0320991 |
| EGR1 | early growth response 1 | -0.0320186 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0318572 |
| LMNA | lamin A/C | -0.0317057 |
| YBX1 | Y box binding protein 1 | -0.0314151 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0312567 |
| MX1 | MX dynamin-like GTPase 1 | -0.0305245 |
| SDC4 | syndecan 4 | -0.0304067 |
| MX2 | MX dynamin-like GTPase 2 | -0.0303016 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0300062 |
| RAI14 | retinoic acid induced 14 | -0.0297357 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0291155 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0281547 |
| CCND1 | cyclin D1 | -0.0280854 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0277708 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0274664 |
| CTSB | cathepsin B | -0.0273937 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.027308 |
| SVIL | supervillin | -0.0273038 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0272428 |
| WASF2 | WAS protein family, member 2 | -0.027167 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0270465 |
| RPL8 | ribosomal protein L8 | -0.0267559 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0264862 |
| KRT8 | keratin 8, type II | -0.0261686 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0260372 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0259304 |
| LAMB3 | laminin, beta 3 | -0.0255744 |
| FTL | ferritin, light polypeptide | -0.0252972 |
| HDLBP | high density lipoprotein binding protein | -0.0252138 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0251381 |
| LAMC2 | laminin, gamma 2 | -0.0240931 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.023976 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0238081 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.023718 |
| CLTC | clathrin, heavy chain (Hc) | -0.0236518 |
| EPCAM | epithelial cell adhesion molecule | -0.0235966 |
| TAPBP | TAP binding protein (tapasin) | -0.0235483 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0234035 |
| RPL34 | ribosomal protein L34 | -0.0232871 |
| SP100 | SP100 nuclear antigen | -0.0232113 |
| ACTN4 | actinin, alpha 4 | -0.0231962 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0230133 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0226995 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0224382 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0224178 |
| PGBD5 | piggyBac transposable element derived 5 | -0.0222062 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0216723 |
| RPS20 | ribosomal protein S20 | -0.0211926 |
| RPS14 | ribosomal protein S14 | -0.0211895 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0211404 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | -0.0211337 |
| ETV6 | ets variant 6 | -0.0209427 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 | -0.0205838 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0205139 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0204015 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.020255 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0202303 |
| HMGB2 | high mobility group box 2 | -0.0201153 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0200608 |
