| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
170 genes differentially expressed following the Captopril_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.182731 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.154067 |
| PDE10A | phosphodiesterase 10A | 0.150951 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.139316 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.13175 |
| ANKRD11 | ankyrin repeat domain 11 | 0.125933 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.123876 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.117823 |
| FMNL2 | formin-like 2 | 0.116475 |
| VIM | vimentin | 0.112805 |
| FLNB | filamin B, beta | 0.111034 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.109302 |
| FAM13A | family with sequence similarity 13, member A | 0.0932528 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0927609 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0895197 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0886325 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0859597 |
| MYOF | myoferlin | 0.0852461 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0832018 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0822447 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0807475 |
| PTK2 | protein tyrosine kinase 2 | 0.079666 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0784722 |
| NDRG1 | N-myc downstream regulated 1 | 0.0769845 |
| NBEAL1 | neurobeachin-like 1 | 0.0718878 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0703403 |
| ATP13A3 | ATPase type 13A3 | 0.0657365 |
| RUNX1 | runt-related transcription factor 1 | 0.0656705 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0637686 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0625158 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0620228 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0619191 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0579505 |
| MED13L | mediator complex subunit 13-like | 0.0578385 |
| SPAG9 | sperm associated antigen 9 | 0.0575607 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0564996 |
| EFNA5 | ephrin-A5 | 0.0559719 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0550466 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0526343 |
| RTN4 | reticulon 4 | 0.052058 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0519727 |
| EGFR | epidermal growth factor receptor | 0.0508646 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.050546 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0492648 |
| RNF145 | ring finger protein 145 | 0.0475497 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0448343 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0419472 |
| PTEN | phosphatase and tensin homolog | 0.0416366 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0400455 |
| PTMA | prothymosin, alpha | 0.0396569 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0391559 |
| MMP1 | matrix metallopeptidase 1 | 0.0383842 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0378321 |
| STC1 | stanniocalcin 1 | 0.0375886 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0363584 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0350227 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0328886 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0325955 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.029674 |
| DST | dystonin | 0.0272778 |
| ASPH | aspartate beta-hydroxylase | 0.0257206 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0247865 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.018858 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0175235 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0174457 |
| PRELID2 | PRELI domain containing 2 | 0.0158819 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.015089 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.013035 |
| RPL11 | ribosomal protein L11 | 0.0123127 |
| LDHA | lactate dehydrogenase A | 0.0108226 |
| RPS8 | ribosomal protein S8 | 0.0102862 |
| ZNF292 | zinc finger protein 292 | 0.0100635 |
| RBM39 | RNA binding motif protein 39 | 0.0097768 |
| PGK1 | phosphoglycerate kinase 1 | 0.0078554 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00694839 |
| JMJD1C | jumonji domain containing 1C | 0.00667425 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.00654647 |
| UBC | ubiquitin C | 0.00452754 |
| LOXL2 | lysyl oxidase-like 2 | 0.00311443 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 8.63073E-4 |
| SETD5 | SET domain containing 5 | 1.72857E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.188999 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.145621 |
| IGF2 | insulin-like growth factor 2 | -0.14068 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.136198 |
| HDLBP | high density lipoprotein binding protein | -0.127172 |
| EXT1 | exostosin glycosyltransferase 1 | -0.118619 |
| SLC38A2 | solute carrier family 38, member 2 | -0.114493 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.111561 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.110067 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.10312 |
| TMSB10 | thymosin beta 10 | -0.10284 |
| AHNAK | AHNAK nucleoprotein | -0.0991764 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0986416 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0983241 |
| RNF213 | ring finger protein 213 | -0.0957108 |
| RPL26 | ribosomal protein L26 | -0.0929363 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.089888 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0880245 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0874954 |
| SYT1 | synaptotagmin I | -0.0814569 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0790927 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.072945 |
| PARD3 | par-3 family cell polarity regulator | -0.0712307 |
| INTS6 | integrator complex subunit 6 | -0.0712118 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.070537 |
| PKM | pyruvate kinase, muscle | -0.0691513 |
| RIGI | RNA sensor RIG-I | -0.0626299 |
| CALR | calreticulin | -0.0614034 |
| PRKCA | protein kinase C, alpha | -0.0612397 |
| GOLGB1 | golgin B1 | -0.0590895 |
| ANO6 | anoctamin 6 | -0.0545094 |
| LMO7 | LIM domain 7 | -0.0506668 |
| MAP1B | microtubule-associated protein 1B | -0.0495993 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0495174 |
| RBM25 | RNA binding motif protein 25 | -0.0490676 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0485604 |
| CCNI | cyclin I | -0.0436495 |
| COL5A2 | collagen, type V, alpha 2 | -0.0430921 |
| FN1 | fibronectin 1 | -0.0430575 |
| NABP1 | nucleic acid binding protein 1 | -0.0429358 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0403669 |
| EGR1 | early growth response 1 | -0.0397132 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0369517 |
| CNKSR3 | CNKSR family member 3 | -0.0367145 |
| B2M | beta-2-microglobulin | -0.0342198 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0315176 |
| NAV1 | neuron navigator 1 | -0.0307719 |
| MYO1E | myosin IE | -0.0305386 |
| RPS6 | ribosomal protein S6 | -0.028892 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0285524 |
| SLC38A1 | solute carrier family 38, member 1 | -0.027553 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0249589 |
| USP34 | ubiquitin specific peptidase 34 | -0.024521 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0230546 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.022892 |
| MT2A | metallothionein 2A | -0.022652 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0202891 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0201487 |
| YAP1 | Yes-associated protein 1 | -0.0201019 |
| OSMR | oncostatin M receptor | -0.019975 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0196054 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0194862 |
| NAV2 | neuron navigator 2 | -0.0187332 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0184379 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0180965 |
| CARD16 | caspase recruitment domain family, member 16 | -0.016893 |
| GPC6 | glypican 6 | -0.0168302 |
| FOXP1 | forkhead box P1 | -0.0165297 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0163642 |
| NF1 | neurofibromin 1 | -0.0159587 |
| HLA-B | major histocompatibility complex, class I, B | -0.0152708 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0141071 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0126556 |
| TXNRD1 | thioredoxin reductase 1 | -0.0115308 |
| ANXA2 | annexin A2 | -0.011221 |
| SBF2 | SET binding factor 2 | -0.0106184 |
| HMGA2 | high mobility group AT-hook 2 | -0.0093216 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.00813896 |
| CMIP | c-Maf inducing protein | -0.00699881 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.00693797 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0066521 |
| GOLGA4 | golgin A4 | -0.00648155 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.00385247 |
| MAP4 | microtubule-associated protein 4 | -0.0034805 |
| S100A9 | S100 calcium binding protein A9 | -0.0032836 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.00271569 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00267793 |
| FNIP1 | folliculin interacting protein 1 | -0.00218772 |
| FTH1 | ferritin, heavy polypeptide 1 | -1.03341E-4 |
