| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Captopril_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.140407 |
| ZNF292 | zinc finger protein 292 | 0.105461 |
| SPAG9 | sperm associated antigen 9 | 0.0992551 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.0864105 |
| VIM | vimentin | 0.0746258 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.073698 |
| PFN1 | profilin 1 | 0.0708681 |
| ANXA5 | annexin A5 | 0.0658857 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0638659 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0636045 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0625088 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0614735 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0555369 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0548237 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0547156 |
| USP3 | ubiquitin specific peptidase 3 | 0.0543707 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0514702 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0505371 |
| MTF2 | metal response element binding transcription factor 2 | 0.0504363 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0496715 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0471896 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0470546 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0467607 |
| RTN4 | reticulon 4 | 0.0454106 |
| MB21D2 | Mab-21 domain containing 2 | 0.0449514 |
| RPL5 | ribosomal protein L5 | 0.0437874 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0430764 |
| MED13L | mediator complex subunit 13-like | 0.0429099 |
| FBXO11 | F-box protein 11 | 0.0405903 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0405098 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0400546 |
| HMGA1 | high mobility group AT-hook 1 | 0.0399425 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0399311 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0397803 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0387816 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0383438 |
| CDH19 | cadherin 19, type 2 | 0.0382184 |
| RASAL2 | RAS protein activator like 2 | 0.0379543 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0374144 |
| CALCR | calcitonin receptor | 0.0373966 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0371998 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0371797 |
| PRR16 | proline rich 16 | 0.0361409 |
| CDC73 | cell division cycle 73 | 0.0360874 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0354668 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0353959 |
| EMP1 | epithelial membrane protein 1 | 0.0352561 |
| ORC4 | origin recognition complex, subunit 4 | 0.0348935 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0346256 |
| TMEM165 | transmembrane protein 165 | 0.0340143 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0337576 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0334762 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0334104 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.032953 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0329321 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.032931 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0324316 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0323555 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0319079 |
| ENAH | enabled homolog (Drosophila) | 0.0318533 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0317176 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0314383 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0313558 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.031168 |
| PDGFC | platelet derived growth factor C | 0.0310563 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0307062 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0305678 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0299744 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0299428 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0298223 |
| MTMR3 | myotubularin related protein 3 | 0.0297822 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0297384 |
| TJP1 | tight junction protein 1 | 0.0296427 |
| MTDH | metadherin | 0.0295939 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.029258 |
| RYBP | RING1 and YY1 binding protein | 0.0291867 |
| SERTAD2 | SERTA domain containing 2 | 0.0290659 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0290153 |
| NUP58 | nucleoporin 58 | 0.0287913 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0287779 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0287681 |
| RHEB | Ras homolog enriched in brain | 0.0285029 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0283263 |
| PTMA | prothymosin, alpha | 0.0274295 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0272864 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.0269697 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0269633 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0268767 |
| RLF | rearranged L-myc fusion | 0.0266767 |
| USP12 | ubiquitin specific peptidase 12 | 0.0266301 |
| GAB2 | GRB2-associated binding protein 2 | 0.0263628 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0262134 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0261136 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0260805 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0258822 |
| RAI1 | retinoic acid induced 1 | 0.0258452 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0258263 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0257552 |
| HBS1L | HBS1-like translational GTPase | 0.0257405 |
| QKI | QKI, KH domain containing, RNA binding | 0.0253395 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | -0.131798 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.121237 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.119875 |
| TMSB10 | thymosin beta 10 | -0.106384 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.104003 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0971851 |
| NTM | neurotrimin | -0.091889 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0898682 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0823702 |
| SNX6 | sorting nexin 6 | -0.0754192 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0744882 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0710144 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0701418 |
| CENPF | centromere protein F, 350/400kDa | -0.0677217 |
| H1-4 | H1.4 linker histone, cluster member | -0.0642454 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0621653 |
| MEIS2 | Meis homeobox 2 | -0.0547687 |
| RPS2 | ribosomal protein S2 | -0.0536603 |
| AHNAK | AHNAK nucleoprotein | -0.0533462 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0533141 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0519758 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0519713 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0507328 |
| MKI67 | marker of proliferation Ki-67 | -0.0506401 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0488313 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.048751 |
| DST | dystonin | -0.0487032 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0474746 |
| CLTC | clathrin, heavy chain (Hc) | -0.0470174 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0449782 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0421232 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0409238 |
| GPC3 | glypican 3 | -0.0401936 |
| ITGAV | integrin, alpha V | -0.0395303 |
| RPL11 | ribosomal protein L11 | -0.0391505 |
| TMSB4X | thymosin beta 4, X-linked | -0.038942 |
| PRKD1 | protein kinase D1 | -0.0388944 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0376686 |
| TFRC | transferrin receptor | -0.0376563 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0375354 |
| H1-5 | H1.5 linker histone, cluster member | -0.0370702 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0369531 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0365754 |
| SMYD3 | SET and MYND domain containing 3 | -0.0365122 |
| STMN1 | stathmin 1 | -0.0365112 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0359354 |
| RPS6 | ribosomal protein S6 | -0.0347378 |
| RPL37 | ribosomal protein L37 | -0.0342328 |
| SET | SET nuclear proto-oncogene | -0.0340171 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0339744 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0339345 |
| HMGB2 | high mobility group box 2 | -0.0337106 |
| COL5A2 | collagen, type V, alpha 2 | -0.0331754 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0331545 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0328512 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0322671 |
| APP | amyloid beta (A4) precursor protein | -0.0318809 |
| RPS19 | ribosomal protein S19 | -0.0317047 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0316991 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0315703 |
| BBX | bobby sox homolog (Drosophila) | -0.0313939 |
| MAP4 | microtubule-associated protein 4 | -0.0312117 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0308793 |
| RPL35A | ribosomal protein L35a | -0.0306938 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0306474 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.030588 |
| COL3A1 | collagen, type III, alpha 1 | -0.030551 |
| ENO1 | enolase 1, (alpha) | -0.0305023 |
| SMC4 | structural maintenance of chromosomes 4 | -0.030329 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0302529 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0302401 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0301355 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0301251 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0301085 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0299443 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0294471 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0289558 |
| EXOC6B | exocyst complex component 6B | -0.0289488 |
| RPL23 | ribosomal protein L23 | -0.0288392 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.02875 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.02866 |
| TPX2 | TPX2, microtubule-associated | -0.0286393 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0286283 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0286004 |
| NKTR | natural killer cell triggering receptor | -0.0285682 |
| UTRN | utrophin | -0.0285571 |
| RPS10 | ribosomal protein S10 | -0.0283813 |
| PNN | pinin, desmosome associated protein | -0.0282252 |
| RPL4 | ribosomal protein L4 | -0.0281899 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0281161 |
| CEP192 | centrosomal protein 192kDa | -0.0278209 |
| H1-0 | H1.0 linker histone | -0.0272316 |
| PDCD5 | programmed cell death 5 | -0.0271625 |
| ARHGAP11A | Rho GTPase activating protein 11A | -0.0270541 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.027053 |
| RPL21 | ribosomal protein L21 | -0.0267864 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0266638 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0265519 |
| CFL2 | cofilin 2 (muscle) | -0.0264307 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0264231 |
