| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Captopril_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.101559 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.101146 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0739218 |
| VCL | vinculin | 0.0632084 |
| ZNF292 | zinc finger protein 292 | 0.0622648 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0616167 |
| TXNIP | thioredoxin interacting protein | 0.0603964 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0601318 |
| FLNB | filamin B, beta | 0.0531554 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0522546 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0514033 |
| SQSTM1 | sequestosome 1 | 0.0504227 |
| B2M | beta-2-microglobulin | 0.0497025 |
| PKM | pyruvate kinase, muscle | 0.0492778 |
| EGFR | epidermal growth factor receptor | 0.0475563 |
| ZNF608 | zinc finger protein 608 | 0.045266 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0449752 |
| NCKAP1 | NCK-associated protein 1 | 0.0446614 |
| PYGB | phosphorylase, glycogen; brain | 0.0434256 |
| PRELID2 | PRELI domain containing 2 | 0.0419012 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0388615 |
| TMSB4X | thymosin beta 4, X-linked | 0.0374263 |
| TJP1 | tight junction protein 1 | 0.0365589 |
| S100A6 | S100 calcium binding protein A6 | 0.0365067 |
| RPS2 | ribosomal protein S2 | 0.034866 |
| RPL12 | ribosomal protein L12 | 0.033646 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0330339 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0327124 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0326933 |
| ECT2 | epithelial cell transforming 2 | 0.0326441 |
| NUP58 | nucleoporin 58 | 0.030604 |
| PDGFC | platelet derived growth factor C | 0.0303476 |
| RNF145 | ring finger protein 145 | 0.0300593 |
| RPL26 | ribosomal protein L26 | 0.029699 |
| PTMA | prothymosin, alpha | 0.0293767 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0286288 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0283904 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0274647 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0265936 |
| MACROD2 | MACRO domain containing 2 | 0.0251814 |
| ARRDC3 | arrestin domain containing 3 | 0.0250229 |
| RHOA | ras homolog family member A | 0.0249347 |
| CCND1 | cyclin D1 | 0.0242371 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.024219 |
| RBM25 | RNA binding motif protein 25 | 0.0241857 |
| ZNF217 | zinc finger protein 217 | 0.0240274 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0238522 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0236321 |
| MT2A | metallothionein 2A | 0.0236243 |
| PFN1 | profilin 1 | 0.0236006 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0236006 |
| DAPK3 | death-associated protein kinase 3 | 0.0233487 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.023106 |
| RPL18 | ribosomal protein L18 | 0.0228091 |
| TXNRD1 | thioredoxin reductase 1 | 0.0222003 |
| TMEM65 | transmembrane protein 65 | 0.0220083 |
| S100A10 | S100 calcium binding protein A10 | 0.021853 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0218221 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0217794 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0217772 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0216454 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0214169 |
| NUP54 | nucleoporin 54kDa | 0.021288 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0212703 |
| RPL23 | ribosomal protein L23 | 0.0212689 |
| PLK2 | polo-like kinase 2 | 0.0210062 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0208641 |
| RPS6 | ribosomal protein S6 | 0.0208628 |
| SERINC1 | serine incorporator 1 | 0.0201694 |
| YEATS2 | YEATS domain containing 2 | 0.0201674 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0201424 |
| ANXA3 | annexin A3 | 0.0201083 |
| HMGA1 | high mobility group AT-hook 1 | 0.0200047 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0199632 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0198611 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0198192 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0196909 |
| SMNDC1 | survival motor neuron domain containing 1 | 0.0195979 |
| RPS12 | ribosomal protein S12 | 0.0193952 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0190356 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0189029 |
| NBAS | neuroblastoma amplified sequence | 0.0185875 |
| TNPO3 | transportin 3 | 0.0185283 |
| RPL36 | ribosomal protein L36 | 0.0182936 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0181428 |
| MEF2A | myocyte enhancer factor 2A | 0.0180185 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0178592 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0178437 |
| RPS8 | ribosomal protein S8 | 0.0178109 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0177797 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0173735 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | 0.0170235 |
| S100A9 | S100 calcium binding protein A9 | 0.0169813 |
| RPL32 | ribosomal protein L32 | 0.0169202 |
| ZFR | zinc finger RNA binding protein | 0.0169187 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0168385 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0163983 |
| JAK2 | Janus kinase 2 | 0.0163915 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0163337 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0162882 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.235711 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.210918 |
| FOXP1 | forkhead box P1 | -0.129102 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.127325 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.124078 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.115566 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.109011 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0973814 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0929743 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.089173 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.081606 |
| NFIA | nuclear factor I/A | -0.0815324 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.07506 |
| NBEA | neurobeachin | -0.0744004 |
| EFNA5 | ephrin-A5 | -0.0735323 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0705662 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0705561 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0666964 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0560896 |
| BMP10 | bone morphogenetic protein 10 | -0.054132 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0528618 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0499085 |
| CUX1 | cut-like homeobox 1 | -0.0494536 |
| EVI5 | ecotropic viral integration site 5 | -0.0480958 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.047141 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0465669 |
| SBF2 | SET binding factor 2 | -0.0464371 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0463321 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0454193 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0425546 |
| MSI2 | musashi RNA-binding protein 2 | -0.042424 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0421939 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.041783 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0407201 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0405895 |
| GPHN | gephyrin | -0.0398235 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0397633 |
| GLI3 | GLI family zinc finger 3 | -0.0395011 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0389563 |
| PDE7B | phosphodiesterase 7B | -0.0374569 |
| TCF12 | transcription factor 12 | -0.0372081 |
| NEBL | nebulette | -0.0371241 |
| NAV2 | neuron navigator 2 | -0.036753 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0354987 |
| ACACA | acetyl-CoA carboxylase alpha | -0.035301 |
| EXOC6B | exocyst complex component 6B | -0.035224 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0349714 |
| CENPF | centromere protein F, 350/400kDa | -0.0333853 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0331526 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0329904 |
| DIAPH3 | diaphanous-related formin 3 | -0.0321327 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0317722 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0315714 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0303504 |
| HDLBP | high density lipoprotein binding protein | -0.0303443 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0298447 |
| NOP58 | NOP58 ribonucleoprotein | -0.0290426 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0289339 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0286993 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0285384 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0280651 |
| DENND1A | DENN/MADD domain containing 1A | -0.0278342 |
| RPL35A | ribosomal protein L35a | -0.0277919 |
| PLXNA1 | plexin A1 | -0.0274259 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0272994 |
| ACTG1 | actin gamma 1 | -0.0270438 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0270092 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0266886 |
| ATXN2 | ataxin 2 | -0.0266253 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0264711 |
| PARD3 | par-3 family cell polarity regulator | -0.0262866 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0261902 |
| TMEM135 | transmembrane protein 135 | -0.0255474 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0250153 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0250032 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.024979 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0249495 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0248564 |
| EHBP1 | EH domain binding protein 1 | -0.0245023 |
| GPATCH8 | G patch domain containing 8 | -0.0244022 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0243503 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0243288 |
| RPL34 | ribosomal protein L34 | -0.0240894 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0240606 |
| CANX | calnexin | -0.024047 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0238951 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0238774 |
| ZNF407 | zinc finger protein 407 | -0.0234766 |
| MORF4L2 | mortality factor 4 like 2 | -0.0232545 |
| SEPTIN9 | septin 9 | -0.0230303 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.0228768 |
| PLCE1 | phospholipase C, epsilon 1 | -0.0227364 |
| ZNF609 | zinc finger protein 609 | -0.0226282 |
| NF1 | neurofibromin 1 | -0.022604 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0225796 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0224792 |
| PUM3 | pumilio RNA binding family member 3 | -0.0224043 |
| NOP56 | NOP56 ribonucleoprotein | -0.0223681 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0223597 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0223083 |
