| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Captopril_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.153414 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.119785 |
| FRMD4A | FERM domain containing 4A | 0.0953347 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.094931 |
| NAV2 | neuron navigator 2 | 0.0926942 |
| RPS12 | ribosomal protein S12 | 0.0890522 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0740856 |
| MT2A | metallothionein 2A | 0.070967 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0694697 |
| PDE10A | phosphodiesterase 10A | 0.0680736 |
| RPS3 | ribosomal protein S3 | 0.0629447 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0613938 |
| ARRDC3 | arrestin domain containing 3 | 0.0594334 |
| MYOF | myoferlin | 0.0591299 |
| RPL5 | ribosomal protein L5 | 0.0566378 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0559048 |
| ZNF292 | zinc finger protein 292 | 0.0548369 |
| RPL23 | ribosomal protein L23 | 0.0537886 |
| ANXA5 | annexin A5 | 0.0534098 |
| ATP13A3 | ATPase type 13A3 | 0.0519744 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0512475 |
| RPL26 | ribosomal protein L26 | 0.0501584 |
| JMJD1C | jumonji domain containing 1C | 0.0495581 |
| RPS8 | ribosomal protein S8 | 0.0491846 |
| FLNB | filamin B, beta | 0.0483146 |
| RPL37A | ribosomal protein L37a | 0.0468074 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0445918 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0425462 |
| CDK19 | cyclin-dependent kinase 19 | 0.0424437 |
| OGA | O-GlcNAcase | 0.0414709 |
| STC1 | stanniocalcin 1 | 0.0409921 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0405738 |
| RPL36A | ribosomal protein L36a | 0.0396847 |
| RPL9 | ribosomal protein L9 | 0.039396 |
| FNIP1 | folliculin interacting protein 1 | 0.0391801 |
| VIM | vimentin | 0.039131 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0391206 |
| B2M | beta-2-microglobulin | 0.0383026 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0382598 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0382482 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0382461 |
| RUNX1 | runt-related transcription factor 1 | 0.0371731 |
| PTMA | prothymosin, alpha | 0.0366943 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0363983 |
| HDAC9 | histone deacetylase 9 | 0.0363371 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0363279 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0361706 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0358079 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0346669 |
| KLF6 | Kruppel-like factor 6 | 0.0345499 |
| RPLP2 | ribosomal protein, large, P2 | 0.034427 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0341474 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0335405 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0329148 |
| GPC6 | glypican 6 | 0.0326657 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0326297 |
| SPAG9 | sperm associated antigen 9 | 0.0321611 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0312301 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0307931 |
| PLPP6 | phospholipid phosphatase 6 | 0.0306968 |
| VEGFA | vascular endothelial growth factor A | 0.03017 |
| RPS17 | ribosomal protein S17 | 0.0300148 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0299805 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0298378 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0296717 |
| SBF2 | SET binding factor 2 | 0.0292313 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0292285 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0291151 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0290675 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0290108 |
| RPL10A | ribosomal protein L10a | 0.0289949 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0287966 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0286962 |
| PRELID2 | PRELI domain containing 2 | 0.0286741 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0286483 |
| RPS25 | ribosomal protein S25 | 0.0286178 |
| SNX9 | sorting nexin 9 | 0.028206 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0280475 |
| MSN | moesin | 0.0278584 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0277244 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0274954 |
| ARFGEF3 | ARFGEF family member 3 | 0.0274706 |
| GOLGA4 | golgin A4 | 0.0272728 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0269699 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0268309 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0267959 |
| RAI1 | retinoic acid induced 1 | 0.0262922 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0261292 |
| SRGN | serglycin | 0.0258673 |
| YEATS2 | YEATS domain containing 2 | 0.0258001 |
| RTN4 | reticulon 4 | 0.0257806 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0256919 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.025595 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0255068 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0252241 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0247586 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0247221 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0246812 |
| SETD5 | SET domain containing 5 | 0.0246296 |
| RNF24 | ring finger protein 24 | 0.0245276 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.281071 |
| FN1 | fibronectin 1 | -0.209506 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.196181 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.135453 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.120554 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.120535 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.1037 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102061 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0877084 |
| GLIS3 | GLIS family zinc finger 3 | -0.0837113 |
| AHNAK | AHNAK nucleoprotein | -0.0751554 |
| TMSB10 | thymosin beta 10 | -0.0684511 |
| CANX | calnexin | -0.0598112 |
| EGR1 | early growth response 1 | -0.0597048 |
| HLA-A | major histocompatibility complex, class I, A | -0.052944 |
| LDHA | lactate dehydrogenase A | -0.0528832 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0462795 |
| TAPBP | TAP binding protein (tapasin) | -0.0433456 |
| UBC | ubiquitin C | -0.0422455 |
| BICC1 | BicC family RNA binding protein 1 | -0.0416747 |
| YBX1 | Y box binding protein 1 | -0.0390714 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0390693 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0373226 |
| CTSD | cathepsin D | -0.0364671 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0349399 |
| PKM | pyruvate kinase, muscle | -0.033145 |
| HMGA2 | high mobility group AT-hook 2 | -0.0329922 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0325128 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0324297 |
| TUBB | tubulin, beta class I | -0.0317034 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0311488 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0299916 |
| MAP1B | microtubule-associated protein 1B | -0.0293319 |
| EXT1 | exostosin glycosyltransferase 1 | -0.02893 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0287071 |
| FTL | ferritin, light polypeptide | -0.0285183 |
| HLA-C | major histocompatibility complex, class I, C | -0.0284648 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0278342 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0275772 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0274435 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0274345 |
| GNAS | GNAS complex locus | -0.0272952 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0263533 |
| IER3 | immediate early response 3 | -0.0259139 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0255297 |
| QKI | QKI, KH domain containing, RNA binding | -0.0253646 |
| LOX | lysyl oxidase | -0.025026 |
| WBP2 | WW domain binding protein 2 | -0.0247511 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0241404 |
| PGK1 | phosphoglycerate kinase 1 | -0.0237458 |
| ACTG1 | actin gamma 1 | -0.0235048 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0234013 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0226278 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0222101 |
| RPL35A | ribosomal protein L35a | -0.0217944 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0214915 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0213182 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0210583 |
| RNF213 | ring finger protein 213 | -0.0209457 |
| ARF1 | ADP-ribosylation factor 1 | -0.0207309 |
| HDLBP | high density lipoprotein binding protein | -0.0204947 |
| RUNX2 | runt-related transcription factor 2 | -0.0198378 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.0197109 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0192334 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0191568 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0191368 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0190665 |
| CCNL1 | cyclin L1 | -0.0190195 |
| DEPP1 | DEPP autophagy regulator 1 | -0.0187276 |
| ATF4 | activating transcription factor 4 | -0.018682 |
| THBS1 | thrombospondin 1 | -0.0186267 |
| CALR | calreticulin | -0.0185261 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0181928 |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | -0.0181869 |
| RPLP0 | ribosomal protein, large, P0 | -0.0181408 |
| SMAD3 | SMAD family member 3 | -0.0181118 |
| CD44 | CD44 molecule (Indian blood group) | -0.0181 |
| TXNIP | thioredoxin interacting protein | -0.0180816 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0177443 |
| CTSB | cathepsin B | -0.0176412 |
| BSG | basigin (Ok blood group) | -0.0176071 |
| GANAB | glucosidase, alpha; neutral AB | -0.0174087 |
| GRN | granulin | -0.0174012 |
| TMEM263 | transmembrane protein 263 | -0.0173858 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0173722 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0172997 |
| COL5A1 | collagen, type V, alpha 1 | -0.0172024 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0169335 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0167858 |
| WDR27 | WD repeat domain 27 | -0.0167738 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0167363 |
| JUN | jun proto-oncogene | -0.0166181 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0165989 |
| MORF4L2 | mortality factor 4 like 2 | -0.0165132 |
| PLIN2 | perilipin 2 | -0.0163368 |
| RIGI | RNA sensor RIG-I | -0.0162999 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0161914 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0161133 |
| RRBP1 | ribosome binding protein 1 | -0.0160924 |
| FLNA | filamin A, alpha | -0.0160753 |
