| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Captopril_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.118323 |
| FAM13A | family with sequence similarity 13, member A | 0.104509 |
| MT2A | metallothionein 2A | 0.0971327 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0924212 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0915468 |
| ZNF292 | zinc finger protein 292 | 0.0798404 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0762729 |
| B2M | beta-2-microglobulin | 0.0762709 |
| PGK1 | phosphoglycerate kinase 1 | 0.0722067 |
| STC1 | stanniocalcin 1 | 0.0690197 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0666335 |
| CD44 | CD44 molecule (Indian blood group) | 0.0627962 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0615472 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0582211 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0578934 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0562466 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0561299 |
| ATP13A3 | ATPase type 13A3 | 0.0531756 |
| FTL | ferritin, light polypeptide | 0.0518064 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0501473 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0488519 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0478341 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0460182 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.044968 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0446874 |
| ANXA2 | annexin A2 | 0.0445748 |
| RBM25 | RNA binding motif protein 25 | 0.044526 |
| RPS8 | ribosomal protein S8 | 0.0444192 |
| TMEM165 | transmembrane protein 165 | 0.0437443 |
| SPAG9 | sperm associated antigen 9 | 0.0428836 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0423188 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0407135 |
| ABI1 | abl-interactor 1 | 0.0395323 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0394202 |
| TFG | TRK-fused gene | 0.0391513 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0391066 |
| RYBP | RING1 and YY1 binding protein | 0.0390132 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0389758 |
| WTAP | Wilms tumor 1 associated protein | 0.038913 |
| RTN4 | reticulon 4 | 0.0384048 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.0382075 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0373115 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0369594 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0369092 |
| RPL26 | ribosomal protein L26 | 0.0357527 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.03569 |
| RBM39 | RNA binding motif protein 39 | 0.0355587 |
| CDC73 | cell division cycle 73 | 0.0355272 |
| TMEM39A | transmembrane protein 39A | 0.0354291 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0350562 |
| RPS24 | ribosomal protein S24 | 0.0345236 |
| RPL34 | ribosomal protein L34 | 0.0333602 |
| MORF4L2 | mortality factor 4 like 2 | 0.033336 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0323598 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0321564 |
| GOLGA4 | golgin A4 | 0.0321199 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0320274 |
| VIM | vimentin | 0.0318813 |
| RLF | rearranged L-myc fusion | 0.0318389 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.031618 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0315783 |
| RPL5 | ribosomal protein L5 | 0.0313619 |
| ANXA5 | annexin A5 | 0.0311029 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0304255 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0303112 |
| RNF114 | ring finger protein 114 | 0.0302771 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0302402 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0300798 |
| MATR3 | matrin 3 | 0.0300033 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0292134 |
| RPS3 | ribosomal protein S3 | 0.0291216 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0291062 |
| ZNF217 | zinc finger protein 217 | 0.0290251 |
| SETD5 | SET domain containing 5 | 0.0286289 |
| RPS12 | ribosomal protein S12 | 0.0285625 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0284819 |
| NF1 | neurofibromin 1 | 0.0284751 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0284643 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0284444 |
| ARRDC3 | arrestin domain containing 3 | 0.0280478 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0279153 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0279077 |
| RPL36 | ribosomal protein L36 | 0.0278423 |
| SERTAD2 | SERTA domain containing 2 | 0.027828 |
| YEATS2 | YEATS domain containing 2 | 0.0275786 |
| PRKD3 | protein kinase D3 | 0.0275443 |
| QKI | QKI, KH domain containing, RNA binding | 0.0272237 |
| RBM6 | RNA binding motif protein 6 | 0.0271629 |
| RPL12 | ribosomal protein L12 | 0.0268205 |
| MTF2 | metal response element binding transcription factor 2 | 0.0268127 |
| PTN | pleiotrophin | 0.0266176 |
| RPS27 | ribosomal protein S27 | 0.026565 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0264739 |
| RPL13A | ribosomal protein L13a | 0.0264326 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0263886 |
| CDK7 | cyclin-dependent kinase 7 | 0.0263034 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0262454 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 0.0262161 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0260875 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0260554 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.278774 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.238866 |
| FN1 | fibronectin 1 | -0.159897 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0894212 |
| MAP1B | microtubule-associated protein 1B | -0.0858561 |
| POTEF | POTE ankyrin domain family, member F | -0.0788719 |
| COL1A1 | collagen, type I, alpha 1 | -0.0749112 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0708413 |
| AHNAK | AHNAK nucleoprotein | -0.0677081 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0676443 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0653424 |
| CANX | calnexin | -0.0653142 |
| PKM | pyruvate kinase, muscle | -0.0627498 |
| C1D | C1D nuclear receptor corepressor | -0.0595113 |
| SEPTIN7 | septin 7 | -0.0584969 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.056543 |
| MSN | moesin | -0.0559739 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0551743 |
| LDHA | lactate dehydrogenase A | -0.0502701 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0489052 |
| SDC4 | syndecan 4 | -0.0485045 |
| ECE1 | endothelin converting enzyme 1 | -0.0476726 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0474384 |
| LOC112694756 | uncharaterized LOC112694756 | -0.045343 |
| HDLBP | high density lipoprotein binding protein | -0.044744 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0439876 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0435496 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0433324 |
| FNIP1 | folliculin interacting protein 1 | -0.0431912 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0430777 |
| SMYD3 | SET and MYND domain containing 3 | -0.042547 |
| ITGAV | integrin, alpha V | -0.0418242 |
| TNS3 | tensin 3 | -0.04127 |
| IL6 | interleukin 6 | -0.0411564 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0395109 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0394995 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0393472 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0388463 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0380695 |
| EGR1 | early growth response 1 | -0.0380308 |
| VEGFC | vascular endothelial growth factor C | -0.0379743 |
| HLA-C | major histocompatibility complex, class I, C | -0.0376373 |
| CDH13 | cadherin 13 | -0.0368091 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0363348 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0357916 |
| HMGA2 | high mobility group AT-hook 2 | -0.035643 |
| VCL | vinculin | -0.0354675 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0354396 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0352609 |
| RRBP1 | ribosome binding protein 1 | -0.034782 |
| ACTN1 | actinin, alpha 1 | -0.0344918 |
| DSTN | destrin (actin depolymerizing factor) | -0.0341765 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0340605 |
| TAGLN2 | transgelin 2 | -0.0340426 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0335599 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0333882 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0327864 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0323465 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0322834 |
| CDK13 | cyclin-dependent kinase 13 | -0.0320385 |
| CENPF | centromere protein F, 350/400kDa | -0.0319016 |
| COL1A2 | collagen, type I, alpha 2 | -0.0318782 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0318551 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0317333 |
| HIRA | histone cell cycle regulator | -0.0317332 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0316528 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0316504 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0316417 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0316323 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0303705 |
| COL5A2 | collagen, type V, alpha 2 | -0.0302251 |
| LOXL2 | lysyl oxidase-like 2 | -0.0300541 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.029779 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0295011 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.029263 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0289556 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0287047 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0286577 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0284383 |
| GSE1 | Gse1 coiled-coil protein | -0.0281359 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0280545 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.02774 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0273513 |
| ACTG1 | actin gamma 1 | -0.0271879 |
| KIF4A | kinesin family member 4A | -0.0271756 |
| LOX | lysyl oxidase | -0.0271073 |
| LMNA | lamin A/C | -0.0270323 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.0269726 |
| KLC1 | kinesin light chain 1 | -0.0267557 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0267121 |
| ATXN1 | ataxin 1 | -0.0266132 |
| MYADM | myeloid-associated differentiation marker | -0.0263892 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0262903 |
| GOLGB1 | golgin B1 | -0.0261531 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.025829 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0256279 |
| CALR | calreticulin | -0.0255911 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | -0.0253989 |
| FBN1 | fibrillin 1 | -0.0251373 |
| CLIC4 | chloride intracellular channel 4 | -0.0250474 |
