| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Captopril perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Captopril_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.137983 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0900356 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0897674 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0866307 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0816806 |
| VEGFA | vascular endothelial growth factor A | 0.0756966 |
| RNF145 | ring finger protein 145 | 0.070391 |
| ANXA5 | annexin A5 | 0.0698448 |
| MT2A | metallothionein 2A | 0.0665959 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0660944 |
| ZNF292 | zinc finger protein 292 | 0.0605167 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.05957 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0576191 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0554081 |
| FAM13A | family with sequence similarity 13, member A | 0.0549846 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0530289 |
| CD109 | CD109 molecule | 0.0530261 |
| NDRG1 | N-myc downstream regulated 1 | 0.0529728 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0494402 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0475111 |
| TMEM165 | transmembrane protein 165 | 0.0467119 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0461694 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0460336 |
| TPR | translocated promoter region, nuclear basket protein | 0.0455143 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0453253 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0441704 |
| PELO | pelota homolog (Drosophila) | 0.0435058 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0430275 |
| NUP58 | nucleoporin 58 | 0.0423604 |
| B2M | beta-2-microglobulin | 0.0420143 |
| HDGF | hepatoma-derived growth factor | 0.0417682 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0415981 |
| AHR | aryl hydrocarbon receptor | 0.0404154 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.04002 |
| SPAG9 | sperm associated antigen 9 | 0.0397492 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0391606 |
| GOLGA4 | golgin A4 | 0.0390368 |
| VMP1 | vacuole membrane protein 1 | 0.0388728 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0384512 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0380566 |
| ARRDC3 | arrestin domain containing 3 | 0.037804 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0376493 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0370368 |
| ATP13A3 | ATPase type 13A3 | 0.0370015 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0368297 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0364617 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0364022 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0358278 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0356569 |
| ETNK1 | ethanolamine kinase 1 | 0.0351301 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0350207 |
| RPS12 | ribosomal protein S12 | 0.0349545 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0348361 |
| SUCO | SUN domain containing ossification factor | 0.034696 |
| CDC73 | cell division cycle 73 | 0.0344365 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0342276 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0337374 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0333344 |
| FNBP1 | formin binding protein 1 | 0.0328384 |
| CENPF | centromere protein F, 350/400kDa | 0.0327671 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0324392 |
| HMGA1 | high mobility group AT-hook 1 | 0.0322748 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0317401 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0314186 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0312621 |
| RBM25 | RNA binding motif protein 25 | 0.0312207 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0309626 |
| RNF24 | ring finger protein 24 | 0.0305145 |
| TOP1 | topoisomerase (DNA) I | 0.0303638 |
| PRELID2 | PRELI domain containing 2 | 0.0300566 |
| SRP54 | signal recognition particle 54kDa | 0.0296371 |
| TNPO3 | transportin 3 | 0.029458 |
| CDCP1 | CUB domain containing protein 1 | 0.0290386 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0286344 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0284103 |
| FOSL1 | FOS-like antigen 1 | 0.0282827 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0279295 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0277631 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0275777 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0273921 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0271789 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0269485 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0265774 |
| WDR26 | WD repeat domain 26 | 0.0264907 |
| SETD5 | SET domain containing 5 | 0.026367 |
| EREG | epiregulin | 0.0262363 |
| CAB39 | calcium binding protein 39 | 0.0262185 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0259178 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0258787 |
| XPO1 | exportin 1 | 0.0256515 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0254787 |
| OGA | O-GlcNAcase | 0.0252104 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0251996 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0251506 |
| PLIN2 | perilipin 2 | 0.0251394 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0248918 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0246575 |
| SMOX | spermine oxidase | 0.0246156 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0244835 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0243925 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.227759 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.198646 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.162272 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.147649 |
| NRG1 | neuregulin 1 | -0.136895 |
| CANX | calnexin | -0.121769 |
| TMSB10 | thymosin beta 10 | -0.120843 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.111995 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0842988 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0793338 |
| ASPH | aspartate beta-hydroxylase | -0.0670628 |
| H1-0 | H1.0 linker histone | -0.0595494 |
| TMSB4X | thymosin beta 4, X-linked | -0.0550345 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0547877 |
| HLA-B | major histocompatibility complex, class I, B | -0.0520788 |
| ARF1 | ADP-ribosylation factor 1 | -0.0464316 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0463696 |
| RPL35A | ribosomal protein L35a | -0.0451182 |
| LOC112694756 | uncharaterized LOC112694756 | -0.044659 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.042877 |
| SYT1 | synaptotagmin I | -0.0423816 |
| AHNAK | AHNAK nucleoprotein | -0.0419277 |
| FTL | ferritin, light polypeptide | -0.0399331 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0391748 |
| LMNA | lamin A/C | -0.0391567 |
| GLIS3 | GLIS family zinc finger 3 | -0.0383457 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0375049 |
| ACTG1 | actin gamma 1 | -0.0371184 |
| RPS19 | ribosomal protein S19 | -0.0367795 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0350428 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0341258 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0325309 |
| IER3 | immediate early response 3 | -0.0323748 |
| GNAS | GNAS complex locus | -0.0321762 |
| RPL34 | ribosomal protein L34 | -0.0317392 |
| MAP1B | microtubule-associated protein 1B | -0.0296416 |
| RNF213 | ring finger protein 213 | -0.0290332 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0285177 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0267165 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0262243 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0261649 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0260815 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0256827 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0255149 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0253626 |
| RPS24 | ribosomal protein S24 | -0.025154 |
| EGR1 | early growth response 1 | -0.0251391 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0249823 |
| HLA-C | major histocompatibility complex, class I, C | -0.0247548 |
| S100A6 | S100 calcium binding protein A6 | -0.0247359 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0247227 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0241661 |
| FBN1 | fibrillin 1 | -0.0234984 |
| SLC38A2 | solute carrier family 38, member 2 | -0.023389 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0231169 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0226226 |
| RPS21 | ribosomal protein S21 | -0.0225976 |
| TCIM | transcriptional and immune response regulator | -0.0222902 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0220177 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0220145 |
| RPL38 | ribosomal protein L38 | -0.0219231 |
| INTS6 | integrator complex subunit 6 | -0.0213619 |
| MT1X | metallothionein 1X | -0.0211325 |
| HLA-A | major histocompatibility complex, class I, A | -0.021016 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0208546 |
| RPLP1 | ribosomal protein, large, P1 | -0.0206223 |
| EZR | ezrin | -0.0206054 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0205941 |
| RASAL2 | RAS protein activator like 2 | -0.0203347 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0200383 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0194697 |
| ATF3 | activating transcription factor 3 | -0.0194288 |
| PALLD | palladin, cytoskeletal associated protein | -0.0191459 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0190082 |
| AOPEP | aminopeptidase O (putative) | -0.0188755 |
| TMEM263 | transmembrane protein 263 | -0.0188577 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0188154 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0187816 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0186017 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0185462 |
| STC2 | stanniocalcin 2 | -0.0185266 |
| APP | amyloid beta (A4) precursor protein | -0.0184532 |
| SFRP1 | secreted frizzled-related protein 1 | -0.018076 |
| FUS | FUS RNA binding protein | -0.0178185 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0177939 |
| NPR2 | natriuretic peptide receptor 2 | -0.0175632 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0172552 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0171113 |
| MX2 | MX dynamin-like GTPase 2 | -0.0170966 |
| RPS9 | ribosomal protein S9 | -0.0169231 |
| RAI14 | retinoic acid induced 14 | -0.0167323 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0167149 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0166649 |
| RPS20 | ribosomal protein S20 | -0.0165893 |
| GLUL | glutamate-ammonia ligase | -0.0165346 |
| AEBP2 | AE binding protein 2 | -0.0164324 |
| UBB | ubiquitin B | -0.0164122 |
| CALR | calreticulin | -0.0163224 |
| HDLBP | high density lipoprotein binding protein | -0.0162344 |
| ACTN4 | actinin, alpha 4 | -0.0162034 |
