| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbamazepine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Carbamazepine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOXL2 | lysyl oxidase-like 2 | 0.189335 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.12912 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.128775 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.110946 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0777326 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0770204 |
| COL3A1 | collagen, type III, alpha 1 | 0.0746902 |
| OGA | O-GlcNAcase | 0.0720748 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0712841 |
| CALR | calreticulin | 0.0702104 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0675388 |
| FBN1 | fibrillin 1 | 0.0638718 |
| VIM | vimentin | 0.062832 |
| FLNB | filamin B, beta | 0.0599653 |
| APP | amyloid beta (A4) precursor protein | 0.0597091 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0596476 |
| SEPTIN9 | septin 9 | 0.0552204 |
| PLAT | plasminogen activator, tissue | 0.0539807 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0492953 |
| THBS2 | thrombospondin 2 | 0.0490763 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0483349 |
| NAV2 | neuron navigator 2 | 0.0454057 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0444432 |
| FLNA | filamin A, alpha | 0.0427605 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0427233 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0426779 |
| SBF2 | SET binding factor 2 | 0.0424558 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0416835 |
| CANX | calnexin | 0.0406788 |
| ATP13A3 | ATPase type 13A3 | 0.0396757 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0392775 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0376563 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0372926 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0367323 |
| CTSB | cathepsin B | 0.0362747 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0347123 |
| COL5A2 | collagen, type V, alpha 2 | 0.0343249 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0340377 |
| MSI2 | musashi RNA-binding protein 2 | 0.0339934 |
| HLA-E | major histocompatibility complex, class I, E | 0.0339515 |
| FNBP4 | formin binding protein 4 | 0.0336984 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0329486 |
| AUTS2 | autism susceptibility candidate 2 | 0.0323164 |
| PTMA | prothymosin, alpha | 0.031824 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.031549 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0312702 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0305325 |
| TMSB4X | thymosin beta 4, X-linked | 0.0301883 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0299192 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0294834 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0294191 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0291011 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0284568 |
| PFKP | phosphofructokinase, platelet | 0.0278562 |
| GOLGA4 | golgin A4 | 0.0276649 |
| ARRDC3 | arrestin domain containing 3 | 0.027418 |
| YEATS2 | YEATS domain containing 2 | 0.0271042 |
| FNIP1 | folliculin interacting protein 1 | 0.0270332 |
| PLEC | plectin | 0.0268087 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0263828 |
| HDLBP | high density lipoprotein binding protein | 0.0262893 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0262707 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.026202 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0262009 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0254676 |
| C1D | C1D nuclear receptor corepressor | 0.0254585 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0250708 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0248762 |
| OPTN | optineurin | 0.0246267 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0244325 |
| STK10 | serine/threonine kinase 10 | 0.0242625 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0242247 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0241514 |
| SFTPA2 | surfactant protein A2 | 0.0240976 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.023736 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0235928 |
| LASP1 | LIM and SH3 protein 1 | 0.022767 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0226126 |
| CD109 | CD109 molecule | 0.0224717 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0223928 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0217818 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0216639 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0215847 |
| AFDN | afadin, adherens junction formation factor | 0.0215823 |
| L1CAM | L1 cell adhesion molecule | 0.0214254 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0213672 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0213447 |
| SQSTM1 | sequestosome 1 | 0.0212299 |
| SH3BP2 | SH3-domain binding protein 2 | 0.0212189 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0210624 |
| HIP1 | huntingtin interacting protein 1 | 0.020953 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0208676 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0208283 |
| FAM219A | family with sequence similarity 219, member A | 0.0208006 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0207274 |
| ACTN4 | actinin, alpha 4 | 0.0206296 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.020367 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.020301 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0202032 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0200394 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.209862 |
| TMSB10 | thymosin beta 10 | -0.111433 |
| NAV1 | neuron navigator 1 | -0.0773752 |
| S100A10 | S100 calcium binding protein A10 | -0.074282 |
| MAP1B | microtubule-associated protein 1B | -0.0733699 |
| MT2A | metallothionein 2A | -0.0682685 |
| POTEF | POTE ankyrin domain family, member F | -0.0680373 |
| LOX | lysyl oxidase | -0.0651151 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0576511 |
| CD44 | CD44 molecule (Indian blood group) | -0.0574856 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0555862 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0514778 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.051332 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0501129 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.047473 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0473633 |
| CDH13 | cadherin 13 | -0.0472334 |
| B2M | beta-2-microglobulin | -0.0451608 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0449233 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0442635 |
| SUCNR1 | succinate receptor 1 | -0.0439493 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0402037 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0398934 |
| PRSS23 | protease, serine, 23 | -0.0394096 |
| RIGI | RNA sensor RIG-I | -0.0383063 |
| FN1 | fibronectin 1 | -0.0374032 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0372849 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0367503 |
| MX2 | MX dynamin-like GTPase 2 | -0.0367224 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0349859 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0343594 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0341836 |
| HLA-B | major histocompatibility complex, class I, B | -0.033527 |
| PFN1 | profilin 1 | -0.0315729 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0312326 |
| SP100 | SP100 nuclear antigen | -0.0302737 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0299308 |
| FTL | ferritin, light polypeptide | -0.0293255 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0286829 |
| CSTB | cystatin B (stefin B) | -0.02862 |
| ACTG1 | actin gamma 1 | -0.0274895 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0272872 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0266773 |
| S100A6 | S100 calcium binding protein A6 | -0.0252615 |
| ASPH | aspartate beta-hydroxylase | -0.0252504 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0250126 |
| RPL28 | ribosomal protein L28 | -0.0249629 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0247216 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.024521 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0244692 |
| DIAPH3 | diaphanous-related formin 3 | -0.0241171 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0235372 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0229836 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.02265 |
| HMGB1 | high mobility group box 1 | -0.0226461 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0221709 |
| PLXNA2 | plexin A2 | -0.0220082 |
| PKM | pyruvate kinase, muscle | -0.0216898 |
| CDK6 | cyclin-dependent kinase 6 | -0.0214942 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0207942 |
| MEIS2 | Meis homeobox 2 | -0.0205664 |
| SEPTIN7 | septin 7 | -0.0204248 |
| EFNA5 | ephrin-A5 | -0.0203281 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0200376 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0200203 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0199427 |
| S100A11 | S100 calcium binding protein A11 | -0.0198738 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0196886 |
| RPS6 | ribosomal protein S6 | -0.0195089 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0194856 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.019315 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0192041 |
| ANXA2 | annexin A2 | -0.0191954 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0190333 |
| RTN4 | reticulon 4 | -0.0190278 |
| RRM2 | ribonucleotide reductase M2 | -0.0188319 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0186674 |
| NEK7 | NIMA-related kinase 7 | -0.0185 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.018457 |
| IL7R | interleukin 7 receptor | -0.0182946 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0179505 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0174411 |
| PMP22 | peripheral myelin protein 22 | -0.0172846 |
| VCL | vinculin | -0.0171241 |
| GLIS3 | GLIS family zinc finger 3 | -0.0170868 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0170468 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0168739 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0165507 |
| RASAL2 | RAS protein activator like 2 | -0.0165325 |
| OSMR | oncostatin M receptor | -0.0162497 |
| RPL35A | ribosomal protein L35a | -0.0161841 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0161808 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0158034 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0156388 |
| SEC61G | Sec61 gamma subunit | -0.0154991 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0154059 |
| MKI67 | marker of proliferation Ki-67 | -0.0153813 |
| CENPF | centromere protein F, 350/400kDa | -0.015376 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0153196 |
| HLA-C | major histocompatibility complex, class I, C | -0.0152307 |
