| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbamazepine perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Carbamazepine_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.393789 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.20467 |
| LOXL2 | lysyl oxidase-like 2 | 0.152885 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.134181 |
| CALR | calreticulin | 0.113369 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.102234 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0857766 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0833232 |
| PLEC | plectin | 0.0823848 |
| VIM | vimentin | 0.0732052 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0710736 |
| VEGFA | vascular endothelial growth factor A | 0.0661677 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0650748 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0638934 |
| SMAD3 | SMAD family member 3 | 0.0560367 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0544101 |
| FLNA | filamin A, alpha | 0.0497962 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0481247 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0479147 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0460033 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0440366 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0432676 |
| RPL7 | ribosomal protein L7 | 0.0421628 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0421151 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0411809 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0401733 |
| APP | amyloid beta (A4) precursor protein | 0.0396111 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0392513 |
| ARRDC3 | arrestin domain containing 3 | 0.0374318 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0356472 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0343234 |
| ACTN4 | actinin, alpha 4 | 0.0329667 |
| MSN | moesin | 0.0328294 |
| HYOU1 | hypoxia up-regulated 1 | 0.032761 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0317608 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0309323 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0305568 |
| RPL19 | ribosomal protein L19 | 0.0295732 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0291619 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0289384 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.027188 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0269715 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.026727 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0266912 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0263392 |
| ECE1 | endothelin converting enzyme 1 | 0.0260211 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0252723 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0248535 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0247984 |
| TMSB4X | thymosin beta 4, X-linked | 0.0246227 |
| ENO1 | enolase 1, (alpha) | 0.0240459 |
| POSTN | periostin, osteoblast specific factor | 0.0240269 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0236614 |
| MCL1 | myeloid cell leukemia 1 | 0.0235909 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0235784 |
| CLIC4 | chloride intracellular channel 4 | 0.0234675 |
| CTSB | cathepsin B | 0.0229838 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0229102 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0228929 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0227769 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0226317 |
| TNS1 | tensin 1 | 0.0224193 |
| MTSS1 | metastasis suppressor 1 | 0.0223491 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0223426 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0219661 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0218205 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0216364 |
| DSPP | dentin sialophosphoprotein | 0.0210136 |
| FAT1 | FAT atypical cadherin 1 | 0.0209597 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0202149 |
| FAM107B | family with sequence similarity 107, member B | 0.0199791 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0197865 |
| BRD2 | bromodomain containing 2 | 0.0196942 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.019636 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0194348 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0193969 |
| RPL3 | ribosomal protein L3 | 0.0191537 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0190546 |
| LRRC59 | leucine rich repeat containing 59 | 0.0187745 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0182755 |
| SEPTIN9 | septin 9 | 0.0182053 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0180383 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0175653 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0172856 |
| SQSTM1 | sequestosome 1 | 0.0171517 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.017063 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0168626 |
| PTMA | prothymosin, alpha | 0.0166563 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0166118 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0165747 |
| HLA-E | major histocompatibility complex, class I, E | 0.0164107 |
| MYO10 | myosin X | 0.0163082 |
| ANXA5 | annexin A5 | 0.0162997 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 0.0162906 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0157839 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0153806 |
| NUCB1 | nucleobindin 1 | 0.015322 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0153197 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0152511 |
| CCDC9 | coiled-coil domain containing 9 | 0.0152293 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.200752 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.13009 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.121312 |
| COL1A2 | collagen, type I, alpha 2 | -0.110826 |
| LOX | lysyl oxidase | -0.0841409 |
| NDRG1 | N-myc downstream regulated 1 | -0.0826871 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0754499 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0685588 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0650422 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0538208 |
| FBN1 | fibrillin 1 | -0.0531162 |
| GLIS3 | GLIS family zinc finger 3 | -0.0515453 |
| MAP1B | microtubule-associated protein 1B | -0.0513671 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0496745 |
| CDH13 | cadherin 13 | -0.0491836 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0449244 |
| HMGA2 | high mobility group AT-hook 2 | -0.0448375 |
| PDE10A | phosphodiesterase 10A | -0.0430516 |
| RPS6 | ribosomal protein S6 | -0.0430114 |
| TMSB10 | thymosin beta 10 | -0.0382194 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0371234 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0364638 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0357146 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0347424 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0341133 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0335736 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0334491 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0331201 |
| ACTG1 | actin gamma 1 | -0.0326697 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0320993 |
| PRR16 | proline rich 16 | -0.0311965 |
| CALD1 | caldesmon 1 | -0.0304592 |
| SMYD3 | SET and MYND domain containing 3 | -0.0301025 |
| GOLGA4 | golgin A4 | -0.0294886 |
| TRAM1 | translocation associated membrane protein 1 | -0.0294578 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0290067 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0280242 |
| OSMR | oncostatin M receptor | -0.0279019 |
| GNAS | GNAS complex locus | -0.0275002 |
| HMCN1 | hemicentin 1 | -0.0271888 |
| MAP4 | microtubule-associated protein 4 | -0.0269299 |
| ASPH | aspartate beta-hydroxylase | -0.0266096 |
| AHNAK | AHNAK nucleoprotein | -0.026602 |
| NRP1 | neuropilin 1 | -0.0261261 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0257888 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0256973 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0255985 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0251584 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0251127 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0249186 |
| VEGFC | vascular endothelial growth factor C | -0.0246609 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0245724 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0244853 |
| PTK2 | protein tyrosine kinase 2 | -0.0244717 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0242699 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0240537 |
| CLMP | CXADR-like membrane protein | -0.0238017 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0237584 |
| SRPK2 | SRSF protein kinase 2 | -0.0234014 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0230319 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0228336 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0227616 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0227244 |
| EHD2 | EH-domain containing 2 | -0.0225991 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.022233 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.02199 |
| BBX | bobby sox homolog (Drosophila) | -0.0215862 |
| NF1 | neurofibromin 1 | -0.0214562 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0213486 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0211288 |
| RASAL2 | RAS protein activator like 2 | -0.021066 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0209378 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0208136 |
| RTN4 | reticulon 4 | -0.0207444 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0207088 |
| ATM | ATM serine/threonine kinase | -0.0206762 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.020457 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0201328 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.020054 |
| WASF2 | WAS protein family, member 2 | -0.0199521 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0199231 |
| COG5 | component of oligomeric golgi complex 5 | -0.0196965 |
| CNTN5 | contactin 5 | -0.0193349 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0192514 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0190701 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0189329 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0189155 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0188535 |
| MYADM | myeloid-associated differentiation marker | -0.0187642 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0186701 |
| NREP | neuronal regeneration related protein | -0.0186234 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0182539 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.018238 |
| OXR1 | oxidation resistance 1 | -0.0179746 |
| SBF2 | SET binding factor 2 | -0.0179667 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0179077 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0179021 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0178944 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.017844 |
| PFN1 | profilin 1 | -0.017633 |
