| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbamazepine perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Carbamazepine_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.426447 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.21951 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.217683 |
| FN1 | fibronectin 1 | 0.189183 |
| DSPP | dentin sialophosphoprotein | 0.18408 |
| C3 | complement component 3 | 0.119953 |
| TF | transferrin | 0.103564 |
| PEG3 | paternally expressed 3 | 0.0980943 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0802141 |
| AHSG | alpha-2-HS-glycoprotein | 0.0642827 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0628314 |
| VEGFA | vascular endothelial growth factor A | 0.0583767 |
| PLIN2 | perilipin 2 | 0.0535718 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0511896 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0452671 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0451558 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.039824 |
| LYZ | lysozyme | 0.0397572 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0385417 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0376346 |
| CPE | carboxypeptidase E | 0.0371321 |
| MT2A | metallothionein 2A | 0.0365987 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0362418 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0354936 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0351088 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0348861 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0346018 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0343803 |
| KRT18 | keratin 18, type I | 0.034236 |
| SLC38A2 | solute carrier family 38, member 2 | 0.032526 |
| FABP1 | fatty acid binding protein 1, liver | 0.0319306 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0312445 |
| RPL7 | ribosomal protein L7 | 0.0311349 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0305377 |
| A2M | alpha-2-macroglobulin | 0.0302871 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0297982 |
| RPL19 | ribosomal protein L19 | 0.0293607 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0283218 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0269666 |
| AFDN | afadin, adherens junction formation factor | 0.026675 |
| KIF5B | kinesin family member 5B | 0.025982 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0257516 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.025153 |
| STC2 | stanniocalcin 2 | 0.0246575 |
| CRY1 | cryptochrome circadian clock 1 | 0.024534 |
| KIF1B | kinesin family member 1B | 0.0244073 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.024137 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0239476 |
| APOA1 | apolipoprotein A-I | 0.0233497 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0228745 |
| PLEC | plectin | 0.022803 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0214338 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0211143 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0209569 |
| VCL | vinculin | 0.020461 |
| LAMB1 | laminin, beta 1 | 0.0204327 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0203352 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0202243 |
| SETD5 | SET domain containing 5 | 0.0201106 |
| INSIG2 | insulin induced gene 2 | 0.0200078 |
| MATN3 | matrilin 3 | 0.0199004 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0197109 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0192766 |
| LRRC59 | leucine rich repeat containing 59 | 0.0191601 |
| DSTN | destrin (actin depolymerizing factor) | 0.0190328 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0189435 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0188317 |
| TRIM26 | tripartite motif containing 26 | 0.0188151 |
| CXXC5 | CXXC finger protein 5 | 0.0183276 |
| APOA2 | apolipoprotein A-II | 0.0183226 |
| GDF15 | growth differentiation factor 15 | 0.0181804 |
| FTL | ferritin, light polypeptide | 0.0179063 |
| SPOPL | speckle-type POZ protein-like | 0.0174047 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0173625 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) | 0.017121 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0171029 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0170658 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0167632 |
| RDX | radixin | 0.0167621 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0166491 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0165944 |
| HSPA1A | heat shock 70kDa protein 1A | 0.016466 |
| RPL11 | ribosomal protein L11 | 0.0164608 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.016418 |
| HLA-A | major histocompatibility complex, class I, A | 0.0162237 |
| ANGPTL8 | angiopoietin like 8 | 0.01613 |
| BAG6 | BCL2-associated athanogene 6 | 0.0160475 |
| HMGA1 | high mobility group AT-hook 1 | 0.0160173 |
| EFNA1 | ephrin-A1 | 0.0159651 |
| SCARB1 | scavenger receptor class B, member 1 | 0.015771 |
| TPI1 | triosephosphate isomerase 1 | 0.0156958 |
| TPM4 | tropomyosin 4 | 0.0156766 |
| FOXO1 | forkhead box O1 | 0.0156511 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0156003 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0155852 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0155352 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.015358 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | 0.0152782 |
| HELZ | helicase with zinc finger | 0.0152629 |
| CTSH | cathepsin H | 0.0151807 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.122615 |
| RPS27A | ribosomal protein S27a | -0.120267 |
| UBC | ubiquitin C | -0.117288 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.101746 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0818318 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0817807 |
| ENO1 | enolase 1, (alpha) | -0.0804552 |
| RPL23 | ribosomal protein L23 | -0.073946 |
| GPC6 | glypican 6 | -0.0671169 |
| SDC4 | syndecan 4 | -0.0645164 |
| RPS24 | ribosomal protein S24 | -0.0622342 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0621157 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0574201 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0527617 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0514662 |
| AHNAK | AHNAK nucleoprotein | -0.0514448 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0510085 |
| JUN | jun proto-oncogene | -0.0490376 |
| SVIL | supervillin | -0.0483217 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0475529 |
| ASPH | aspartate beta-hydroxylase | -0.0472178 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0462657 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0459645 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0449536 |
| KRT8 | keratin 8, type II | -0.0436911 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0436287 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0429376 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0428262 |
| TMSB10 | thymosin beta 10 | -0.0411655 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0400076 |
| TXNRD1 | thioredoxin reductase 1 | -0.0378966 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0377902 |
| RPL34 | ribosomal protein L34 | -0.0374772 |
| VMP1 | vacuole membrane protein 1 | -0.0373346 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0368679 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.0363883 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0357531 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0349485 |
| FRMD5 | FERM domain containing 5 | -0.0346294 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0343349 |
| MALRD1 | MAM and LDL receptor class A domain containing 1 | -0.033835 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0327352 |
| RPS21 | ribosomal protein S21 | -0.0325497 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0321872 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0320128 |
| SMYD3 | SET and MYND domain containing 3 | -0.031954 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.03189 |
| FUS | FUS RNA binding protein | -0.0318792 |
| TNS3 | tensin 3 | -0.031431 |
| RIGI | RNA sensor RIG-I | -0.0306865 |
| PTMA | prothymosin, alpha | -0.030651 |
| FOXP1 | forkhead box P1 | -0.0305518 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0305113 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0304995 |
| INTS6 | integrator complex subunit 6 | -0.0302166 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.030085 |
| RPL38 | ribosomal protein L38 | -0.0299164 |
| USP34 | ubiquitin specific peptidase 34 | -0.0296893 |
| JMJD1C | jumonji domain containing 1C | -0.0296195 |
| ZNF638 | zinc finger protein 638 | -0.0295825 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0292072 |
| ATXN1 | ataxin 1 | -0.0290841 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0286848 |
| CNKSR3 | CNKSR family member 3 | -0.0285776 |
| GLG1 | golgi glycoprotein 1 | -0.0281768 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0279952 |
| PARD3 | par-3 family cell polarity regulator | -0.0278758 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0278406 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0276962 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0267508 |
| LCN2 | lipocalin 2 | -0.0266023 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0264657 |
| RPS8 | ribosomal protein S8 | -0.0263842 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0263194 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0262729 |
| ANO6 | anoctamin 6 | -0.0260623 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0258978 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0258663 |
| EHBP1 | EH domain binding protein 1 | -0.025599 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.025571 |
| CANX | calnexin | -0.0254338 |
| MAP1B | microtubule-associated protein 1B | -0.0253961 |
| EXOC6B | exocyst complex component 6B | -0.0251832 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0251777 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0249146 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0248031 |
| SP100 | SP100 nuclear antigen | -0.0244867 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0244458 |
| GPHN | gephyrin | -0.0243792 |
| SKI | SKI proto-oncogene | -0.0242029 |
| OSMR | oncostatin M receptor | -0.0238417 |
| MRTFA | myocardin related transcription factor A | -0.0237517 |
| COG5 | component of oligomeric golgi complex 5 | -0.0237273 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0237043 |
| EXOC4 | exocyst complex component 4 | -0.0236855 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0236717 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0235562 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0235088 |
| RPS15 | ribosomal protein S15 | -0.0233088 |
| PRKCA | protein kinase C, alpha | -0.0227752 |
