| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbamazepine perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Carbamazepine_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.278535 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0535784 |
| LOXL2 | lysyl oxidase-like 2 | 0.0514433 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0425815 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0375007 |
| TMSB4X | thymosin beta 4, X-linked | 0.0368286 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0366422 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0354788 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0340775 |
| PYGL | phosphorylase, glycogen, liver | 0.0303357 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0283936 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0282821 |
| PLIN2 | perilipin 2 | 0.0276176 |
| LDHA | lactate dehydrogenase A | 0.0272791 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0269756 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0265086 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0262089 |
| EPHA4 | EPH receptor A4 | 0.0261155 |
| CALR | calreticulin | 0.0251477 |
| HDAC9 | histone deacetylase 9 | 0.0235157 |
| KRT18 | keratin 18, type I | 0.0233211 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.023282 |
| ITGB4 | integrin, beta 4 | 0.0232553 |
| MYOF | myoferlin | 0.0232435 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0225407 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0223772 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0222271 |
| PLEC | plectin | 0.0219679 |
| PLK2 | polo-like kinase 2 | 0.0219008 |
| RNF213 | ring finger protein 213 | 0.0214462 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0213284 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0212364 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0209536 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0208368 |
| LASP1 | LIM and SH3 protein 1 | 0.020298 |
| CANX | calnexin | 0.0201535 |
| FLNA | filamin A, alpha | 0.0200264 |
| RGS4 | regulator of G-protein signaling 4 | 0.0195204 |
| EFNA5 | ephrin-A5 | 0.0182698 |
| EGFR | epidermal growth factor receptor | 0.0180935 |
| APP | amyloid beta (A4) precursor protein | 0.0179242 |
| HDLBP | high density lipoprotein binding protein | 0.0178313 |
| FLNB | filamin B, beta | 0.0176504 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0175659 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.01726 |
| FNBP4 | formin binding protein 4 | 0.0167875 |
| ANXA2 | annexin A2 | 0.0164831 |
| JUN | jun proto-oncogene | 0.0161276 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0157109 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0156522 |
| CEP250 | centrosomal protein 250kDa | 0.015652 |
| CD109 | CD109 molecule | 0.01563 |
| MCL1 | myeloid cell leukemia 1 | 0.0154595 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0153631 |
| OGA | O-GlcNAcase | 0.0152381 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.014865 |
| VCL | vinculin | 0.0148581 |
| KLF6 | Kruppel-like factor 6 | 0.0146948 |
| PODXL | podocalyxin-like | 0.0145507 |
| ACTN4 | actinin, alpha 4 | 0.0145369 |
| SMAD3 | SMAD family member 3 | 0.0143204 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0139642 |
| AEBP2 | AE binding protein 2 | 0.0136767 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.013364 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0132726 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0131225 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0130789 |
| NDRG1 | N-myc downstream regulated 1 | 0.0128088 |
| STK17A | serine/threonine kinase 17a | 0.0127044 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0124819 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0123292 |
| MYO18A | myosin XVIIIA | 0.0123142 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0123054 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0122882 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0122782 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 0.0120761 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0120278 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0120152 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0114945 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0114456 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.011401 |
| BEGAIN | brain-enriched guanylate kinase-associated | 0.0113854 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 0.0113093 |
| TRERF1 | transcriptional regulating factor 1 | 0.0112977 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0112388 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0111225 |
| INF2 | inverted formin, FH2 and WH2 domain containing | 0.0111081 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0108849 |
| EPHA2 | EPH receptor A2 | 0.010711 |
| DCTN1 | dynactin 1 | 0.0105938 |
| INTS6 | integrator complex subunit 6 | 0.0105604 |
| ABR | active BCR-related | 0.0103395 |
| MAPT | microtubule-associated protein tau | 0.010226 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0101908 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0101625 |
| GANAB | glucosidase, alpha; neutral AB | 0.0101353 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0100948 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.00988056 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.00985427 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.00983704 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.29637 |
| MT2A | metallothionein 2A | -0.179559 |
| RPS6 | ribosomal protein S6 | -0.102866 |
| TP63 | tumor protein p63 | -0.100354 |
| POTEF | POTE ankyrin domain family, member F | -0.0956536 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.076407 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0758966 |
| TXNRD1 | thioredoxin reductase 1 | -0.0754784 |
| RPS19 | ribosomal protein S19 | -0.0724659 |
| HLA-B | major histocompatibility complex, class I, B | -0.0680278 |
| RPS8 | ribosomal protein S8 | -0.067909 |
| RPL35A | ribosomal protein L35a | -0.0655256 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0579072 |
| TMSB10 | thymosin beta 10 | -0.0568872 |
| RPL36 | ribosomal protein L36 | -0.0556712 |
| RPLP2 | ribosomal protein, large, P2 | -0.0556357 |
| PTMA | prothymosin, alpha | -0.0531324 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0528962 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0511059 |
| MT1E | metallothionein 1E | -0.0510946 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0497793 |
| USP34 | ubiquitin specific peptidase 34 | -0.0490457 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0489897 |
| RPL38 | ribosomal protein L38 | -0.0481959 |
| RPL37A | ribosomal protein L37a | -0.0476292 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0471095 |
| RPL26 | ribosomal protein L26 | -0.0465367 |
| RPS23 | ribosomal protein S23 | -0.0463647 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0462741 |
| RPL28 | ribosomal protein L28 | -0.0459369 |
| FTL | ferritin, light polypeptide | -0.045243 |
| RPS2 | ribosomal protein S2 | -0.0445155 |
| RPL31 | ribosomal protein L31 | -0.0441146 |
| RPL23 | ribosomal protein L23 | -0.0435591 |
| MT1X | metallothionein 1X | -0.0429579 |
| SRGN | serglycin | -0.0415432 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0410741 |
| RPS29 | ribosomal protein S29 | -0.0389764 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.038581 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.038546 |
| RPS13 | ribosomal protein S13 | -0.0384979 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.038191 |
| S100A9 | S100 calcium binding protein A9 | -0.0371879 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0371824 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0356898 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0355302 |
| RPL12 | ribosomal protein L12 | -0.035406 |
| SRPK2 | SRSF protein kinase 2 | -0.0346739 |
| RPLP1 | ribosomal protein, large, P1 | -0.0343139 |
| RPL34 | ribosomal protein L34 | -0.0338244 |
| RPS21 | ribosomal protein S21 | -0.0337403 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0337057 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0334003 |
| RPS15 | ribosomal protein S15 | -0.0333532 |
| RPL36A | ribosomal protein L36a | -0.0332202 |
| JMJD1C | jumonji domain containing 1C | -0.0331261 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0331114 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0329574 |
| RPS10 | ribosomal protein S10 | -0.0329557 |
| RPS12 | ribosomal protein S12 | -0.0328347 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0325122 |
| RTN4 | reticulon 4 | -0.0319786 |
| ACTG1 | actin gamma 1 | -0.0319266 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.031875 |
| RPL37 | ribosomal protein L37 | -0.0316602 |
| YBX3 | Y box binding protein 3 | -0.0315611 |
| MATR3 | matrin 3 | -0.0315503 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0315201 |
| TMEM41B | transmembrane protein 41B | -0.0314323 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0306004 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0304393 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0297772 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0297604 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0287584 |
| RPL8 | ribosomal protein L8 | -0.0286332 |
| B2M | beta-2-microglobulin | -0.0283021 |
| RPL32 | ribosomal protein L32 | -0.0282848 |
| RPL35 | ribosomal protein L35 | -0.0282159 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0279723 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0274514 |
| VMP1 | vacuole membrane protein 1 | -0.0273263 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0270818 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.026924 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0268634 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0265917 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0265435 |
| SPAG9 | sperm associated antigen 9 | -0.0263762 |
| RPS27 | ribosomal protein S27 | -0.0262466 |
| CLTC | clathrin, heavy chain (Hc) | -0.0259191 |
| RPL7A | ribosomal protein L7a | -0.0257996 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0257992 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0255045 |
| FBXO11 | F-box protein 11 | -0.0254452 |
| FUS | FUS RNA binding protein | -0.0251986 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0249531 |
| PFN1 | profilin 1 | -0.0249382 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0248689 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0247985 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0245792 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0241474 |
