| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbamazepine perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Carbamazepine_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.133991 |
| MCL1 | myeloid cell leukemia 1 | 0.10456 |
| LAMC2 | laminin, gamma 2 | 0.0925102 |
| PLEC | plectin | 0.0882605 |
| SPAG9 | sperm associated antigen 9 | 0.0850358 |
| LAMB3 | laminin, beta 3 | 0.0782024 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.077312 |
| SLTM | SAFB-like, transcription modulator | 0.0691743 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0644696 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0620934 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0562951 |
| KRT18 | keratin 18, type I | 0.0560303 |
| ARGLU1 | arginine and glutamate rich 1 | 0.054406 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0543524 |
| ARRDC3 | arrestin domain containing 3 | 0.0522098 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0484239 |
| DSPP | dentin sialophosphoprotein | 0.0479386 |
| CES1 | carboxylesterase 1 | 0.0479247 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0470803 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0445627 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.043218 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0429874 |
| LMO7 | LIM domain 7 | 0.0411343 |
| EGFR | epidermal growth factor receptor | 0.0397654 |
| RNF213 | ring finger protein 213 | 0.0394582 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0391301 |
| RPL7 | ribosomal protein L7 | 0.0387791 |
| PGK1 | phosphoglycerate kinase 1 | 0.038733 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0370229 |
| MYO1E | myosin IE | 0.0362171 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0361035 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0352125 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0351699 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0349203 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0346431 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0338559 |
| SMAD3 | SMAD family member 3 | 0.0330325 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0323996 |
| VCL | vinculin | 0.0323561 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0323312 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.031324 |
| ANXA2 | annexin A2 | 0.0308507 |
| MKI67 | marker of proliferation Ki-67 | 0.030808 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0307737 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0305038 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0302009 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0300314 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0299886 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0299435 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0299022 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0292275 |
| MAP7 | microtubule-associated protein 7 | 0.0289738 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0281808 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0281613 |
| ANO6 | anoctamin 6 | 0.0276294 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.027507 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0262152 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0260068 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0259705 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0257181 |
| ABLIM1 | actin binding LIM protein 1 | 0.0257113 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0255378 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0254432 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0253114 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0252367 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0251994 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0250733 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0248169 |
| FAT1 | FAT atypical cadherin 1 | 0.0247678 |
| HOMER1 | homer scaffolding protein 1 | 0.0246753 |
| USP53 | ubiquitin specific peptidase 53 | 0.0243212 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0242081 |
| ATP13A3 | ATPase type 13A3 | 0.0241799 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0241238 |
| LAMA4 | laminin, alpha 4 | 0.0238563 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0238278 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0235107 |
| RAB7A | RAB7A, member RAS oncogene family | 0.023021 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0228763 |
| PYGL | phosphorylase, glycogen, liver | 0.0228257 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0227961 |
| BMP6 | bone morphogenetic protein 6 | 0.0227585 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0226572 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0225855 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0225702 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.022288 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0222802 |
| MYO5B | myosin VB | 0.0221059 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0218467 |
| RUNX1 | runt-related transcription factor 1 | 0.0217715 |
| ADAR | adenosine deaminase, RNA-specific | 0.0216945 |
| OGA | O-GlcNAcase | 0.0215081 |
| GRB10 | growth factor receptor-bound protein 10 | 0.021058 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0209346 |
| SQSTM1 | sequestosome 1 | 0.020724 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0206483 |
| CASC3 | cancer susceptibility candidate 3 | 0.0201967 |
| KIAA1217 | KIAA1217 | 0.0201666 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.0199545 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0197232 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.31022 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.141994 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.130092 |
| MT2A | metallothionein 2A | -0.0954278 |
| TXNRD1 | thioredoxin reductase 1 | -0.0895982 |
| UBC | ubiquitin C | -0.0820852 |
| TMSB10 | thymosin beta 10 | -0.0652659 |
| PKM | pyruvate kinase, muscle | -0.0639631 |
| RPS27A | ribosomal protein S27a | -0.0511603 |
| ASPH | aspartate beta-hydroxylase | -0.0509337 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0497319 |
| SEC61G | Sec61 gamma subunit | -0.0486375 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0445663 |
| NDRG1 | N-myc downstream regulated 1 | -0.0440401 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0432778 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0428553 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0426327 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0425918 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0411847 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0384187 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0382567 |
| RPS3 | ribosomal protein S3 | -0.0376983 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0360604 |
| GRAMD1B | GRAM domain containing 1B | -0.0353377 |
| SCEL | sciellin | -0.0349819 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0347992 |
| FTL | ferritin, light polypeptide | -0.0331445 |
| ACTG1 | actin gamma 1 | -0.0311872 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.030649 |
| CCNI | cyclin I | -0.0305541 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0294506 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.028663 |
| POTEF | POTE ankyrin domain family, member F | -0.0278359 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0272223 |
| BPTF | bromodomain PHD finger transcription factor | -0.0271339 |
| LDHA | lactate dehydrogenase A | -0.0270044 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0267899 |
| TMEM165 | transmembrane protein 165 | -0.0266545 |
| RPL23 | ribosomal protein L23 | -0.0265908 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0262714 |
| CAV2 | caveolin 2 | -0.0262329 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0260444 |
| FOXP1 | forkhead box P1 | -0.0258628 |
| RBM25 | RNA binding motif protein 25 | -0.0253909 |
| ANKRD12 | ankyrin repeat domain 12 | -0.025145 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0250871 |
| ZNF638 | zinc finger protein 638 | -0.0250769 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0249154 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.0248227 |
| TAOK1 | TAO kinase 1 | -0.024504 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0241252 |
| MGAT4C | MGAT4 family, member C | -0.0235218 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0231401 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0229453 |
| TAOK3 | TAO kinase 3 | -0.022826 |
| MT1X | metallothionein 1X | -0.0227554 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0225947 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0224172 |
| RPL35A | ribosomal protein L35a | -0.0223828 |
| PCBP2 | poly(rC) binding protein 2 | -0.0223265 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0221713 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0221645 |
| RPLP1 | ribosomal protein, large, P1 | -0.0219505 |
| SMYD3 | SET and MYND domain containing 3 | -0.0218192 |
| HM13 | histocompatibility (minor) 13 | -0.0216336 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0215666 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0213147 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0207933 |
| RPL37A | ribosomal protein L37a | -0.0207695 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0207198 |
| SEC24D | SEC24 family member D | -0.0206548 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0205638 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0202721 |
| GOLGA4 | golgin A4 | -0.0200296 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0199174 |
| MYOF | myoferlin | -0.0199162 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0197306 |
| EXOC6B | exocyst complex component 6B | -0.0197124 |
| RPS6 | ribosomal protein S6 | -0.0196529 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0191522 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0190369 |
| PHF21A | PHD finger protein 21A | -0.0189125 |
| PFN1 | profilin 1 | -0.0188517 |
| SON | SON DNA binding protein | -0.0186997 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0186204 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0185873 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0185674 |
| THOC2 | THO complex 2 | -0.0184907 |
| FRYL | FRY-like | -0.0184745 |
| PARD3 | par-3 family cell polarity regulator | -0.0184627 |
| S100A10 | S100 calcium binding protein A10 | -0.0184299 |
| PTEN | phosphatase and tensin homolog | -0.018281 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0182773 |
| BBX | bobby sox homolog (Drosophila) | -0.0182152 |
| PHKB | phosphorylase kinase, beta | -0.0177966 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.0177841 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0177694 |
| RPL31 | ribosomal protein L31 | -0.0177095 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0177011 |
| SCFD1 | sec1 family domain containing 1 | -0.0176856 |
