| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbamazepine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Carbamazepine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0865173 |
| TXNRD1 | thioredoxin reductase 1 | 0.0696594 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0666493 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0619968 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0603101 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0601927 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0549894 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0479758 |
| WDR43 | WD repeat domain 43 | 0.0455069 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0447619 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0442577 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0439449 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0428461 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0428313 |
| PM20D1 | peptidase M20 domain containing 1 | 0.042797 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0389843 |
| TPM3 | tropomyosin 3 | 0.0382733 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0370244 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0369015 |
| RTN4 | reticulon 4 | 0.0367845 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0366981 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0366458 |
| RPL7 | ribosomal protein L7 | 0.0344942 |
| GRAMD1B | GRAM domain containing 1B | 0.0343994 |
| FGB | fibrinogen beta chain | 0.0307179 |
| CANX | calnexin | 0.0300003 |
| CALR | calreticulin | 0.0298533 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0285684 |
| RPL19 | ribosomal protein L19 | 0.0280435 |
| RPL4 | ribosomal protein L4 | 0.0280322 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0278266 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0268676 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0267941 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0266092 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0263777 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0263117 |
| APP | amyloid beta (A4) precursor protein | 0.0259237 |
| KLF6 | Kruppel-like factor 6 | 0.0253162 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0253086 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0252262 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0242781 |
| ILF2 | interleukin enhancer binding factor 2 | 0.023956 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0238066 |
| ANLN | anillin, actin binding protein | 0.0236549 |
| TPX2 | TPX2, microtubule-associated | 0.0233528 |
| ECT2 | epithelial cell transforming 2 | 0.0232564 |
| DENND4A | DENN/MADD domain containing 4A | 0.0232105 |
| HYOU1 | hypoxia up-regulated 1 | 0.0231176 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0230144 |
| FAM168A | family with sequence similarity 168, member A | 0.0228296 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0226369 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0224419 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0221896 |
| WBP11 | WW domain binding protein 11 | 0.021926 |
| RHEB | Ras homolog enriched in brain | 0.0218474 |
| YBX3 | Y box binding protein 3 | 0.0215869 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.0213698 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0212378 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0210094 |
| YME1L1 | YME1-like 1 ATPase | 0.020712 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0204282 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0200677 |
| NOL10 | nucleolar protein 10 | 0.0199372 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0196271 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0195505 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0195193 |
| PFDN2 | prefoldin subunit 2 | 0.0194979 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.019492 |
| RRM2 | ribonucleotide reductase M2 | 0.0192308 |
| XPO1 | exportin 1 | 0.0190372 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0189275 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0185112 |
| SPAG5 | sperm associated antigen 5 | 0.0184297 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0181666 |
| CTNNBL1 | catenin, beta like 1 | 0.0181062 |
| RBM8A | RNA binding motif protein 8A | 0.0180964 |
| NUP58 | nucleoporin 58 | 0.0180887 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0179491 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0178578 |
| JAK1 | Janus kinase 1 | 0.0178164 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0178005 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0177288 |
| USP3 | ubiquitin specific peptidase 3 | 0.0176599 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0176106 |
| ACLY | ATP citrate lyase | 0.0175543 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.017543 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.0172712 |
| CASC3 | cancer susceptibility candidate 3 | 0.0172202 |
| SPAG9 | sperm associated antigen 9 | 0.0169563 |
| FLNA | filamin A, alpha | 0.0169186 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0168072 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0167005 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0166757 |
| FBL | fibrillarin | 0.0165985 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0165742 |
| RPS7 | ribosomal protein S7 | 0.0165345 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0164888 |
| RPL3 | ribosomal protein L3 | 0.0164668 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0163817 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0162589 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.330589 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.209182 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.149985 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0904032 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0891972 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0848511 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0839948 |
| TMSB10 | thymosin beta 10 | -0.0830841 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0749021 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0732385 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0660277 |
| FTL | ferritin, light polypeptide | -0.0646153 |
| ACTG1 | actin gamma 1 | -0.063333 |
| FMNL2 | formin-like 2 | -0.0572451 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0517326 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.051586 |
| PARD3 | par-3 family cell polarity regulator | -0.0502696 |
| RPS6 | ribosomal protein S6 | -0.0465815 |
| HLA-B | major histocompatibility complex, class I, B | -0.0462452 |
| RPL23 | ribosomal protein L23 | -0.043663 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0429649 |
| S100A6 | S100 calcium binding protein A6 | -0.0404164 |
| EGFR | epidermal growth factor receptor | -0.0402742 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.039918 |
| RBM25 | RNA binding motif protein 25 | -0.0397671 |
| RPLP1 | ribosomal protein, large, P1 | -0.0394171 |
| IGF2 | insulin-like growth factor 2 | -0.0393054 |
| NDRG1 | N-myc downstream regulated 1 | -0.0391862 |
| RPS8 | ribosomal protein S8 | -0.0384978 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0384594 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.038366 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0360295 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0359288 |
| FLNB | filamin B, beta | -0.0356891 |
| RPL35A | ribosomal protein L35a | -0.0356545 |
| IER3 | immediate early response 3 | -0.034499 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0343538 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0330285 |
| PYGL | phosphorylase, glycogen, liver | -0.032793 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0324167 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0319594 |
| LDHA | lactate dehydrogenase A | -0.0312618 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0310659 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0305288 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0303207 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0298391 |
| NEBL | nebulette | -0.0296222 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0291342 |
| PFN1 | profilin 1 | -0.0288004 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0286422 |
| POTEF | POTE ankyrin domain family, member F | -0.0284235 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.028175 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0277379 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0274959 |
| S100A10 | S100 calcium binding protein A10 | -0.0274065 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0273861 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0267866 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.026606 |
| IL6 | interleukin 6 | -0.0262861 |
| HLA-A | major histocompatibility complex, class I, A | -0.0258444 |
| RPS19 | ribosomal protein S19 | -0.0256151 |
| RPL31 | ribosomal protein L31 | -0.0255471 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0253795 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0253569 |
| GOLGA4 | golgin A4 | -0.025063 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0248677 |
| RPL37A | ribosomal protein L37a | -0.024825 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0242245 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0241302 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0237583 |
| SNX14 | sorting nexin 14 | -0.0229514 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0229432 |
| EXT1 | exostosin glycosyltransferase 1 | -0.02292 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0227468 |
| EGR1 | early growth response 1 | -0.0223407 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.022032 |
| NF1 | neurofibromin 1 | -0.0217246 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.021691 |
| MAP1B | microtubule-associated protein 1B | -0.0215067 |
| CMIP | c-Maf inducing protein | -0.0215058 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0214566 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0213181 |
| COPA | coatomer protein complex, subunit alpha | -0.0211853 |
| CD44 | CD44 molecule (Indian blood group) | -0.0210974 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0208257 |
| MT1X | metallothionein 1X | -0.0208181 |
| NRG1 | neuregulin 1 | -0.0207528 |
| RAB2A | RAB2A, member RAS oncogene family | -0.020673 |
| NBEAL1 | neurobeachin-like 1 | -0.020504 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0204609 |
| RPS21 | ribosomal protein S21 | -0.0203666 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0202923 |
| MORF4L2 | mortality factor 4 like 2 | -0.0201183 |
| NUMB | numb homolog (Drosophila) | -0.0199127 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0197079 |
| MYO1E | myosin IE | -0.0196677 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0196369 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.019558 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0195291 |
| DENND5B | DENN/MADD domain containing 5B | -0.0194555 |
