| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbamazepine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Carbamazepine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.282724 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.221093 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.220298 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.189315 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.154114 |
| CALR | calreticulin | 0.138436 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.116934 |
| PLEC | plectin | 0.103089 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.100398 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0895975 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0853124 |
| MSN | moesin | 0.0824226 |
| VEGFA | vascular endothelial growth factor A | 0.0813036 |
| PTMA | prothymosin, alpha | 0.0763797 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0673689 |
| TMF1 | TATA element modulatory factor 1 | 0.066275 |
| TPM3 | tropomyosin 3 | 0.0658542 |
| TMSB4X | thymosin beta 4, X-linked | 0.065454 |
| MYO6 | myosin VI | 0.0612105 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0606721 |
| PCBP2 | poly(rC) binding protein 2 | 0.0575917 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0574415 |
| DSPP | dentin sialophosphoprotein | 0.0564875 |
| G0S2 | G0/G1 switch 2 | 0.0544357 |
| ARRDC3 | arrestin domain containing 3 | 0.0538452 |
| YTHDC1 | YTH domain containing 1 | 0.0534612 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0509537 |
| FLNA | filamin A, alpha | 0.049793 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0487719 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0486432 |
| KRT18 | keratin 18, type I | 0.0474188 |
| MCL1 | myeloid cell leukemia 1 | 0.04492 |
| CANX | calnexin | 0.0447384 |
| ACTN4 | actinin, alpha 4 | 0.0444331 |
| RPL19 | ribosomal protein L19 | 0.0435399 |
| UBC | ubiquitin C | 0.043439 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0426722 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0424869 |
| LDHA | lactate dehydrogenase A | 0.042379 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0423068 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0418853 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0408432 |
| RPL7 | ribosomal protein L7 | 0.0401303 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0397531 |
| CTSB | cathepsin B | 0.0388007 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0386193 |
| RAI14 | retinoic acid induced 14 | 0.038391 |
| RNF145 | ring finger protein 145 | 0.0380574 |
| RCOR1 | REST corepressor 1 | 0.0380107 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.037568 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.037303 |
| SFTPA2 | surfactant protein A2 | 0.0372506 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0369829 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.036245 |
| VIM | vimentin | 0.0361453 |
| LAMB3 | laminin, beta 3 | 0.0357165 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0353043 |
| BRD2 | bromodomain containing 2 | 0.0352805 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0350469 |
| CD9 | CD9 molecule | 0.0350029 |
| COPA | coatomer protein complex, subunit alpha | 0.0349006 |
| HDGF | hepatoma-derived growth factor | 0.034821 |
| RNF213 | ring finger protein 213 | 0.0346878 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.034562 |
| CTTN | cortactin | 0.0341745 |
| FNBP4 | formin binding protein 4 | 0.0339814 |
| RPL3 | ribosomal protein L3 | 0.0336135 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0333405 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0330838 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0328916 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0325405 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0322889 |
| IRF6 | interferon regulatory factor 6 | 0.0321057 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0317743 |
| APP | amyloid beta (A4) precursor protein | 0.0317406 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0315696 |
| MKRN1 | makorin ring finger protein 1 | 0.0308752 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0306588 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0306029 |
| POTEF | POTE ankyrin domain family, member F | 0.0302197 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0300366 |
| SET | SET nuclear proto-oncogene | 0.0297179 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0296307 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0295114 |
| FLNB | filamin B, beta | 0.0293555 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0287801 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0287195 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0286667 |
| CNN3 | calponin 3, acidic | 0.0285885 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0284218 |
| TPI1 | triosephosphate isomerase 1 | 0.028277 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0282653 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0279905 |
| DUSP5 | dual specificity phosphatase 5 | 0.0277096 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0276804 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0276327 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0275804 |
| HLA-A | major histocompatibility complex, class I, A | 0.0275677 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0275534 |
| HSPA1B | heat shock 70kDa protein 1B | 0.0275046 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.282621 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.155432 |
| ACTG1 | actin gamma 1 | -0.104343 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0976874 |
| RPL35A | ribosomal protein L35a | -0.0964486 |
| RPL34 | ribosomal protein L34 | -0.0796482 |
| TMSB10 | thymosin beta 10 | -0.067596 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0523279 |
| NDRG1 | N-myc downstream regulated 1 | -0.0519391 |
| RPS6 | ribosomal protein S6 | -0.0506418 |
| RPL23 | ribosomal protein L23 | -0.0505683 |
| RPLP1 | ribosomal protein, large, P1 | -0.0499366 |
| RPL9 | ribosomal protein L9 | -0.0494076 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0484418 |
| RPS24 | ribosomal protein S24 | -0.047151 |
| RPLP0 | ribosomal protein, large, P0 | -0.0462543 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0459586 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0451583 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0432132 |
| TXNRD1 | thioredoxin reductase 1 | -0.0430594 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0423749 |
| RPL32 | ribosomal protein L32 | -0.0361155 |
| RPL12 | ribosomal protein L12 | -0.0347665 |
| RPL30 | ribosomal protein L30 | -0.0345104 |
| RPS21 | ribosomal protein S21 | -0.0341984 |
| RACK1 | receptor for activated C kinase 1 | -0.0340542 |
| RPS8 | ribosomal protein S8 | -0.0336909 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0331887 |
| CCNI | cyclin I | -0.0330759 |
| SDC4 | syndecan 4 | -0.0328262 |
| MT2A | metallothionein 2A | -0.032274 |
| RPL37 | ribosomal protein L37 | -0.0319552 |
| RPL38 | ribosomal protein L38 | -0.0318056 |
| RPL8 | ribosomal protein L8 | -0.0314154 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.031015 |
| S100A10 | S100 calcium binding protein A10 | -0.0307251 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0302241 |
| EFNA5 | ephrin-A5 | -0.0302022 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0301931 |
| RPS15 | ribosomal protein S15 | -0.029077 |
| RPS19 | ribosomal protein S19 | -0.0288202 |
| CD2AP | CD2-associated protein | -0.0286398 |
| RUNX1 | runt-related transcription factor 1 | -0.0285334 |
| RPL11 | ribosomal protein L11 | -0.0281717 |
| RPS13 | ribosomal protein S13 | -0.0272706 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0272503 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0270456 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0270414 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.026762 |
| KIAA1217 | KIAA1217 | -0.0265537 |
| RPS23 | ribosomal protein S23 | -0.0264148 |
| RPS27A | ribosomal protein S27a | -0.0263807 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0262119 |
| SYT1 | synaptotagmin I | -0.0260539 |
| TMEM263 | transmembrane protein 263 | -0.025394 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.025236 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.025227 |
| OSMR | oncostatin M receptor | -0.0250728 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0248838 |
| GNAS | GNAS complex locus | -0.0248454 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.024744 |
| AHNAK | AHNAK nucleoprotein | -0.024706 |
| RPS5 | ribosomal protein S5 | -0.024582 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0243586 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0240491 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0240119 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0235934 |
| FAM3C | family with sequence similarity 3, member C | -0.0235857 |
| S100A9 | S100 calcium binding protein A9 | -0.0235241 |
| RPL28 | ribosomal protein L28 | -0.0229784 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.0229392 |
| ZFR | zinc finger RNA binding protein | -0.022877 |
| FHIT | fragile histidine triad | -0.0228588 |
| CDK17 | cyclin-dependent kinase 17 | -0.0228464 |
| EGR1 | early growth response 1 | -0.0225691 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0223219 |
| ATXN1 | ataxin 1 | -0.0221704 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0221097 |
| HMGB1 | high mobility group box 1 | -0.0219303 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0216317 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0214978 |
| RPL31 | ribosomal protein L31 | -0.0214547 |
| PARD3 | par-3 family cell polarity regulator | -0.0213728 |
| IL6ST | interleukin 6 signal transducer | -0.0210814 |
| KRT7 | keratin 7, type II | -0.0206562 |
| RPS29 | ribosomal protein S29 | -0.0204532 |
| MATR3 | matrin 3 | -0.0204366 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.020391 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0202217 |
| RPL27 | ribosomal protein L27 | -0.0201773 |
| CHMP2B | charged multivesicular body protein 2B | -0.0201257 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0200949 |
| NPC2 | Niemann-Pick disease, type C2 | -0.0200592 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0195808 |
| RPL26 | ribosomal protein L26 | -0.019485 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0194608 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0194413 |
| ZNF292 | zinc finger protein 292 | -0.0193621 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0193079 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0193068 |
