| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbamazepine perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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136 genes differentially expressed following the Carbamazepine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EIF1 | eukaryotic translation initiation factor 1 | 0.124044 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.116547 |
| NDRG1 | N-myc downstream regulated 1 | 0.0971143 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.094391 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.094241 |
| ERBIN | erbb2 interacting protein | 0.084317 |
| ZNF292 | zinc finger protein 292 | 0.0839921 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.072912 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.071064 |
| PTMA | prothymosin, alpha | 0.0710227 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0666152 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.065946 |
| PTK2 | protein tyrosine kinase 2 | 0.0642726 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0612884 |
| RLF | rearranged L-myc fusion | 0.0597886 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0576476 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0574256 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.056205 |
| LMO7 | LIM domain 7 | 0.0561044 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0544541 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0540639 |
| SPAG9 | sperm associated antigen 9 | 0.0529646 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0509485 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0508827 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0482056 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0445331 |
| RPS3 | ribosomal protein S3 | 0.0431367 |
| FTL | ferritin, light polypeptide | 0.0428345 |
| GOLGA4 | golgin A4 | 0.0412778 |
| SETD5 | SET domain containing 5 | 0.040069 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0396057 |
| RPL19 | ribosomal protein L19 | 0.0395855 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0371087 |
| RPL23 | ribosomal protein L23 | 0.0360284 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0350734 |
| NUP58 | nucleoporin 58 | 0.034223 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0321177 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0319072 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0307062 |
| UBC | ubiquitin C | 0.030626 |
| USP34 | ubiquitin specific peptidase 34 | 0.0304797 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0297374 |
| ACTN4 | actinin, alpha 4 | 0.0269045 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0260529 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.025282 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0250616 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0238971 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0208667 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.01958 |
| PGK1 | phosphoglycerate kinase 1 | 0.0195232 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0191925 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0170303 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0170166 |
| HELZ | helicase with zinc finger | 0.0144474 |
| PARD3 | par-3 family cell polarity regulator | 0.013749 |
| MT2A | metallothionein 2A | 0.0124253 |
| TPI1 | triosephosphate isomerase 1 | 0.012031 |
| RPS27A | ribosomal protein S27a | 0.0114021 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00966429 |
| ANXA2 | annexin A2 | 0.00801188 |
| RPL31 | ribosomal protein L31 | 0.00732164 |
| PKM | pyruvate kinase, muscle | 0.00700808 |
| CCNI | cyclin I | 0.00671174 |
| RSF1 | remodeling and spacing factor 1 | 0.00647789 |
| LDHA | lactate dehydrogenase A | 0.0064142 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.00498893 |
| PFN1 | profilin 1 | 0.00390839 |
| SRPK2 | SRSF protein kinase 2 | 0.00340509 |
| RPS12 | ribosomal protein S12 | 0.00181485 |
| FNDC3B | fibronectin type III domain containing 3B | 5.50001E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.191331 |
| FN1 | fibronectin 1 | -0.180936 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.151183 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.113136 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.112778 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.102607 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.101854 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.100104 |
| TMSB10 | thymosin beta 10 | -0.0992867 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0862913 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0833003 |
| PDE10A | phosphodiesterase 10A | -0.081499 |
| INHBA | inhibin, beta A | -0.0734991 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0695807 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0583548 |
| GPHN | gephyrin | -0.0570967 |
| CDH13 | cadherin 13 | -0.0569761 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0525022 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0498825 |
| VIM | vimentin | -0.0498347 |
| GPC6 | glypican 6 | -0.049299 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0483845 |
| EGFR | epidermal growth factor receptor | -0.0479933 |
| ASPH | aspartate beta-hydroxylase | -0.0447922 |
| ENO1 | enolase 1, (alpha) | -0.0433853 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0422331 |
| MED13L | mediator complex subunit 13-like | -0.0368307 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0356779 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0329333 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0304113 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0294527 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0273165 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0266266 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0263068 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0260151 |
| CD44 | CD44 molecule (Indian blood group) | -0.0258633 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0253042 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0228721 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0220731 |
| SMYD3 | SET and MYND domain containing 3 | -0.0213281 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0189375 |
| CUX1 | cut-like homeobox 1 | -0.0187024 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0180179 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.016289 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0158892 |
| MYOF | myoferlin | -0.0152335 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0150636 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0144763 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0141263 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0137482 |
| EFNA5 | ephrin-A5 | -0.00978966 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.00965804 |
| DST | dystonin | -0.00951022 |
| ANKRD12 | ankyrin repeat domain 12 | -0.00891571 |
| DOCK5 | dedicator of cytokinesis 5 | -0.00887284 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.00814222 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.00787499 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.00632412 |
| RPS6 | ribosomal protein S6 | -0.0055421 |
| MCL1 | myeloid cell leukemia 1 | -0.00508558 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.00392934 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.00390568 |
| RTN4 | reticulon 4 | -0.00325171 |
| RPL11 | ribosomal protein L11 | -0.00180149 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.00152658 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.00131822 |