| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbamazepine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Carbamazepine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.321825 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.318862 |
| FN1 | fibronectin 1 | 0.230597 |
| VIM | vimentin | 0.159278 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.143552 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0986167 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0984755 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0983447 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.08651 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0806786 |
| OGA | O-GlcNAcase | 0.0798222 |
| ADM | adrenomedullin | 0.0785971 |
| NDRG1 | N-myc downstream regulated 1 | 0.0766263 |
| ARRDC3 | arrestin domain containing 3 | 0.0764734 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0763442 |
| NAV2 | neuron navigator 2 | 0.0722939 |
| MYOF | myoferlin | 0.0711184 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0686759 |
| FLNA | filamin A, alpha | 0.0675071 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0655351 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.062442 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0605995 |
| LOXL2 | lysyl oxidase-like 2 | 0.0604974 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0599197 |
| MSN | moesin | 0.0594096 |
| PDE10A | phosphodiesterase 10A | 0.0587066 |
| APP | amyloid beta (A4) precursor protein | 0.058196 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.057845 |
| CALR | calreticulin | 0.057674 |
| SFTPA2 | surfactant protein A2 | 0.057414 |
| HLA-E | major histocompatibility complex, class I, E | 0.0557446 |
| CADM1 | cell adhesion molecule 1 | 0.0522271 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0520097 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0517448 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0480466 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0467638 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0450071 |
| VEGFA | vascular endothelial growth factor A | 0.0420944 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0416752 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0415715 |
| FLNB | filamin B, beta | 0.041354 |
| CEP250 | centrosomal protein 250kDa | 0.0409745 |
| RNF213 | ring finger protein 213 | 0.040265 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0398052 |
| ANXA2 | annexin A2 | 0.039659 |
| ANLN | anillin, actin binding protein | 0.0394167 |
| PGK1 | phosphoglycerate kinase 1 | 0.0389708 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0385069 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0382558 |
| TMSB4X | thymosin beta 4, X-linked | 0.0381334 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.037929 |
| SMAD3 | SMAD family member 3 | 0.0376573 |
| OPTN | optineurin | 0.0364812 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.036398 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0357233 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.034915 |
| SPAG9 | sperm associated antigen 9 | 0.0348686 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0345168 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0334565 |
| FBXO32 | F-box protein 32 | 0.0332478 |
| CANX | calnexin | 0.0332397 |
| GOLGA4 | golgin A4 | 0.0328068 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.032774 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0325628 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0318699 |
| STC1 | stanniocalcin 1 | 0.0316191 |
| CTSB | cathepsin B | 0.03106 |
| RBM39 | RNA binding motif protein 39 | 0.0305343 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0304715 |
| FMNL2 | formin-like 2 | 0.030189 |
| LDHA | lactate dehydrogenase A | 0.0291492 |
| PFKP | phosphofructokinase, platelet | 0.0290199 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0288399 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0287334 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0286508 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0282433 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0279334 |
| PCBP2 | poly(rC) binding protein 2 | 0.0272026 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0269368 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0268947 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0267681 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0263237 |
| PHF21A | PHD finger protein 21A | 0.0263142 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0262481 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0262332 |
| ACTN4 | actinin, alpha 4 | 0.0261409 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0261189 |
| SERINC1 | serine incorporator 1 | 0.0260905 |
| SDC4 | syndecan 4 | 0.0255249 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0254863 |
| ARFGEF3 | ARFGEF family member 3 | 0.0254335 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0251699 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0249092 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0248289 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.024685 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0244174 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0241429 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0241074 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0240723 |
| MCL1 | myeloid cell leukemia 1 | 0.0240648 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.137415 |
| GLIS3 | GLIS family zinc finger 3 | -0.0852983 |
| FTL | ferritin, light polypeptide | -0.0680143 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0612048 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0567411 |
| HLA-B | major histocompatibility complex, class I, B | -0.0531616 |
| RPS6 | ribosomal protein S6 | -0.0528154 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0524145 |
| RPS24 | ribosomal protein S24 | -0.0497269 |
| RPL23 | ribosomal protein L23 | -0.0492648 |
| TMSB10 | thymosin beta 10 | -0.0475653 |
| HMGA2 | high mobility group AT-hook 2 | -0.045735 |
| BICC1 | BicC family RNA binding protein 1 | -0.0455855 |
| MT2A | metallothionein 2A | -0.0448108 |
| RPL35A | ribosomal protein L35a | -0.0430905 |
| RPL9 | ribosomal protein L9 | -0.0428992 |
| RPLP1 | ribosomal protein, large, P1 | -0.0397125 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0394506 |
| CDH13 | cadherin 13 | -0.0364313 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0363098 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0359877 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0358134 |
| RPL37A | ribosomal protein L37a | -0.0357238 |
| RPS8 | ribosomal protein S8 | -0.0327493 |
| VCL | vinculin | -0.0316902 |
| RPLP2 | ribosomal protein, large, P2 | -0.030824 |
| IER3 | immediate early response 3 | -0.0301077 |
| RPS19 | ribosomal protein S19 | -0.029885 |
| PALLD | palladin, cytoskeletal associated protein | -0.0297136 |
| RPS3 | ribosomal protein S3 | -0.0297042 |
| RPS12 | ribosomal protein S12 | -0.0290773 |
| CD44 | CD44 molecule (Indian blood group) | -0.0273162 |
| TMEM132D | transmembrane protein 132D | -0.0260727 |
| GPC6 | glypican 6 | -0.0256973 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0256309 |
| FRMD4A | FERM domain containing 4A | -0.0255544 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0247934 |
| NABP1 | nucleic acid binding protein 1 | -0.0246907 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0245334 |
| KYNU | kynureninase | -0.0243243 |
| RPL31 | ribosomal protein L31 | -0.0235038 |
| RPL26 | ribosomal protein L26 | -0.0233538 |
| COL1A1 | collagen, type I, alpha 1 | -0.0233453 |
| ACTG1 | actin gamma 1 | -0.0231777 |
| RPS16 | ribosomal protein S16 | -0.0231531 |
| EFNA5 | ephrin-A5 | -0.0221207 |
| RACK1 | receptor for activated C kinase 1 | -0.0220723 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0218037 |
| RPL35 | ribosomal protein L35 | -0.0217391 |
| OSMR | oncostatin M receptor | -0.0216976 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0216944 |
| ASTN2 | astrotactin 2 | -0.0216861 |
| RPL11 | ribosomal protein L11 | -0.0214364 |
| ASPH | aspartate beta-hydroxylase | -0.0212416 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0212152 |
| TAPBP | TAP binding protein (tapasin) | -0.0211707 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.021114 |
| S100A9 | S100 calcium binding protein A9 | -0.0210523 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0209775 |
| RPS13 | ribosomal protein S13 | -0.0208436 |
| RPL36 | ribosomal protein L36 | -0.0202692 |
| PLSCR1 | phospholipid scramblase 1 | -0.0197999 |
| RPL34 | ribosomal protein L34 | -0.0196883 |
| INTS6 | integrator complex subunit 6 | -0.0196353 |
| FLOT1 | flotillin 1 | -0.0195583 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0191709 |
| SMYD3 | SET and MYND domain containing 3 | -0.0190904 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0190671 |
| RPL28 | ribosomal protein L28 | -0.0188106 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0185345 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0181434 |
| RPS27 | ribosomal protein S27 | -0.018078 |
| LOX | lysyl oxidase | -0.0180361 |
| MORF4L2 | mortality factor 4 like 2 | -0.0180035 |
| RPL39 | ribosomal protein L39 | -0.0179473 |
| CTSD | cathepsin D | -0.0178601 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0178569 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0178314 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0177979 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0175058 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0174981 |
| EGR1 | early growth response 1 | -0.0174818 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0173535 |
| SLC38A2 | solute carrier family 38, member 2 | -0.017324 |
| NAV1 | neuron navigator 1 | -0.0173175 |
| RPS14 | ribosomal protein S14 | -0.0171093 |
| RPL27 | ribosomal protein L27 | -0.0169026 |
| RPLP0 | ribosomal protein, large, P0 | -0.0168265 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0165485 |
| RPS5 | ribosomal protein S5 | -0.0157427 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0155864 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0155718 |
| INHBA | inhibin, beta A | -0.0153451 |
| RPL12 | ribosomal protein L12 | -0.0152948 |
| RPS29 | ribosomal protein S29 | -0.0152731 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0151747 |
| PARD3 | par-3 family cell polarity regulator | -0.0151531 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | -0.0149708 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0149395 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0149194 |
