| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbamazepine perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Carbamazepine_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.10148 |
| FN1 | fibronectin 1 | 0.0965593 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0820282 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0770374 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0744722 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0529826 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0517439 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0504822 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0495016 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0491878 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0481151 |
| MSN | moesin | 0.0462175 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0457919 |
| IL6 | interleukin 6 | 0.0451377 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0437761 |
| RPL19 | ribosomal protein L19 | 0.0427673 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0422467 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0413409 |
| CALR | calreticulin | 0.039187 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0382303 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0359809 |
| RUNX1 | runt-related transcription factor 1 | 0.0346147 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.034499 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0339415 |
| SETD5 | SET domain containing 5 | 0.0334844 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0326632 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0322612 |
| YTHDC1 | YTH domain containing 1 | 0.031757 |
| ANXA5 | annexin A5 | 0.031131 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0306061 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0305692 |
| CCNL1 | cyclin L1 | 0.0299101 |
| BBX | bobby sox homolog (Drosophila) | 0.0297379 |
| NAV2 | neuron navigator 2 | 0.0295851 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0293801 |
| ARRDC3 | arrestin domain containing 3 | 0.0293248 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0291747 |
| GPR107 | G protein-coupled receptor 107 | 0.0289226 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0287886 |
| SEC24B | SEC24 family member B | 0.0281902 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0280433 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0280259 |
| ATP13A3 | ATPase type 13A3 | 0.0279746 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0279289 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0272379 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0271743 |
| FMNL2 | formin-like 2 | 0.0271446 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0270075 |
| FBN1 | fibrillin 1 | 0.0263765 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0263118 |
| PLEC | plectin | 0.0262479 |
| NUP54 | nucleoporin 54kDa | 0.0261971 |
| TLN1 | talin 1 | 0.0261754 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0258328 |
| SPPL3 | signal peptide peptidase like 3 | 0.0258284 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.025138 |
| PRRC2C | proline-rich coiled-coil 2C | 0.024606 |
| RNF145 | ring finger protein 145 | 0.0242407 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0241607 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0241219 |
| DST | dystonin | 0.0240569 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0240472 |
| MCL1 | myeloid cell leukemia 1 | 0.0238764 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.023857 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0236289 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0234965 |
| RNF114 | ring finger protein 114 | 0.0234731 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0233501 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0230867 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0230416 |
| FAM13A | family with sequence similarity 13, member A | 0.0229757 |
| RPL37 | ribosomal protein L37 | 0.0227586 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0224767 |
| WDR26 | WD repeat domain 26 | 0.0223853 |
| IGF2 | insulin-like growth factor 2 | 0.0223574 |
| NKTR | natural killer cell triggering receptor | 0.0223339 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 0.0222952 |
| MSI2 | musashi RNA-binding protein 2 | 0.0222769 |
| RYBP | RING1 and YY1 binding protein | 0.0222399 |
| FLNA | filamin A, alpha | 0.0221275 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0221143 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0221142 |
| YME1L1 | YME1-like 1 ATPase | 0.0221082 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0220296 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0219754 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0219041 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0218647 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0217165 |
| HYOU1 | hypoxia up-regulated 1 | 0.0216561 |
| RORA | RAR-related orphan receptor A | 0.0212935 |
| MMP12 | matrix metallopeptidase 12 | 0.0210435 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0209983 |
| USP36 | ubiquitin specific peptidase 36 | 0.0208165 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0204174 |
| TPM3 | tropomyosin 3 | 0.0203828 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0203531 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0203514 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0203459 |
| WDR1 | WD repeat domain 1 | 0.0201729 |
| RBM27 | RNA binding motif protein 27 | 0.0200532 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.299969 |
| MT2A | metallothionein 2A | -0.144813 |
| MAP1B | microtubule-associated protein 1B | -0.106423 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0947012 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0933239 |
| HLA-B | major histocompatibility complex, class I, B | -0.0878498 |
| COL1A1 | collagen, type I, alpha 1 | -0.0816346 |
| TMSB10 | thymosin beta 10 | -0.078037 |
| POTEF | POTE ankyrin domain family, member F | -0.0650036 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0633335 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.055307 |
| STC1 | stanniocalcin 1 | -0.0541131 |
| LOC112694756 | uncharaterized LOC112694756 | -0.051645 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0511794 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0506457 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0494913 |
| COL1A2 | collagen, type I, alpha 2 | -0.0466703 |
| MYOF | myoferlin | -0.0454316 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0451929 |
| CALU | calumenin | -0.0447901 |
| CANX | calnexin | -0.0447585 |
| S100A10 | S100 calcium binding protein A10 | -0.0415921 |
| RRBP1 | ribosome binding protein 1 | -0.040346 |
| HLA-C | major histocompatibility complex, class I, C | -0.0402036 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0397338 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0395588 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0394957 |
| GLIS3 | GLIS family zinc finger 3 | -0.0394484 |
| ENO1 | enolase 1, (alpha) | -0.0394386 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0394031 |
| ANXA2 | annexin A2 | -0.0387159 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0376297 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0376009 |
| CCNI | cyclin I | -0.0367572 |
| GNAS | GNAS complex locus | -0.0367555 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0359716 |
| CDK6 | cyclin-dependent kinase 6 | -0.0359489 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.035379 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0349933 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0340137 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0339681 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0339439 |
| FAM20C | family with sequence similarity 20, member C | -0.0332565 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0325531 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0325175 |
| RPL28 | ribosomal protein L28 | -0.0313343 |
| AHNAK | AHNAK nucleoprotein | -0.0313303 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0312883 |
| SEPTIN7 | septin 7 | -0.0312776 |
| SRP54 | signal recognition particle 54kDa | -0.0309924 |
| MT1X | metallothionein 1X | -0.0300037 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0296792 |
| HMGB1 | high mobility group box 1 | -0.0295288 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0294349 |
| CD44 | CD44 molecule (Indian blood group) | -0.0282785 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0281236 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0280113 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.027417 |
| SON | SON DNA binding protein | -0.0273428 |
| PRSS23 | protease, serine, 23 | -0.0272154 |
| RPS23 | ribosomal protein S23 | -0.0270978 |
| GLG1 | golgi glycoprotein 1 | -0.0270976 |
| SEC24D | SEC24 family member D | -0.0270876 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0266828 |
| RAD51B | RAD51 paralog B | -0.0265166 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0264767 |
| EXOC4 | exocyst complex component 4 | -0.026466 |
| TUBA1B | tubulin, alpha 1b | -0.0259734 |
| TUBB | tubulin, beta class I | -0.025882 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0256406 |
| RPS21 | ribosomal protein S21 | -0.0250219 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0250167 |
| S100A9 | S100 calcium binding protein A9 | -0.0247328 |
| DIAPH3 | diaphanous-related formin 3 | -0.0247273 |
| HM13 | histocompatibility (minor) 13 | -0.0245492 |
| ARF1 | ADP-ribosylation factor 1 | -0.0244715 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0242987 |
| LDHA | lactate dehydrogenase A | -0.0239582 |
| FTL | ferritin, light polypeptide | -0.0237436 |
| PKM | pyruvate kinase, muscle | -0.0236611 |
| S100A6 | S100 calcium binding protein A6 | -0.0236147 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0236046 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0234962 |
| MEF2A | myocyte enhancer factor 2A | -0.0232986 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0232258 |
| INTS6 | integrator complex subunit 6 | -0.0230585 |
| H3-3B | H3.3 histone B | -0.0229401 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0228869 |
| NAV1 | neuron navigator 1 | -0.0228829 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0226715 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0225634 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0225366 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0224955 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0224909 |
| PTMA | prothymosin, alpha | -0.0224717 |
| UBC | ubiquitin C | -0.022372 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0221938 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0219988 |
| SEPTIN2 | septin 2 | -0.0219039 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0218241 |
