| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbamazepine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Carbamazepine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0977579 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0902172 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0789935 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0688125 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0668639 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0641139 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0568778 |
| CANX | calnexin | 0.0558855 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0552628 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0547699 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0542869 |
| NUP58 | nucleoporin 58 | 0.0537732 |
| TPX2 | TPX2, microtubule-associated | 0.0529665 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0513731 |
| TXNRD1 | thioredoxin reductase 1 | 0.048559 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0464476 |
| KIAA1958 | KIAA1958 | 0.046093 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0453734 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0444554 |
| ANLN | anillin, actin binding protein | 0.0441453 |
| CEP250 | centrosomal protein 250kDa | 0.043523 |
| ARRDC3 | arrestin domain containing 3 | 0.0434698 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0430111 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0428865 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0418629 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.039017 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0389034 |
| CENPF | centromere protein F, 350/400kDa | 0.0378898 |
| YAP1 | Yes-associated protein 1 | 0.0372136 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0366772 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0366573 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.036519 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0363132 |
| SETD5 | SET domain containing 5 | 0.0356786 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0356093 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0352896 |
| CALU | calumenin | 0.0351773 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0351606 |
| PCBP2 | poly(rC) binding protein 2 | 0.035046 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0349963 |
| YBX3 | Y box binding protein 3 | 0.0349519 |
| CAPRIN2 | caprin family member 2 | 0.0347544 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.033722 |
| SPAG9 | sperm associated antigen 9 | 0.0336643 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0334925 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0332922 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0326757 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0322875 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0322564 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0313877 |
| RPL4 | ribosomal protein L4 | 0.0311513 |
| FLNA | filamin A, alpha | 0.0307148 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0306272 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0304334 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0296352 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0293364 |
| CUL3 | cullin 3 | 0.0293292 |
| BRD2 | bromodomain containing 2 | 0.0293158 |
| GOLGA2 | golgin A2 | 0.0290836 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0288591 |
| MKI67 | marker of proliferation Ki-67 | 0.0285635 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0284615 |
| RBM39 | RNA binding motif protein 39 | 0.028371 |
| AURKA | aurora kinase A | 0.0282028 |
| KIF4A | kinesin family member 4A | 0.028054 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0278206 |
| UBQLN1 | ubiquilin 1 | 0.0277809 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0275171 |
| HDLBP | high density lipoprotein binding protein | 0.0273776 |
| DAND5 | DAN domain family member 5, BMP antagonist | 0.0273045 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0270333 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0269963 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0269896 |
| RRBP1 | ribosome binding protein 1 | 0.0268714 |
| SET | SET nuclear proto-oncogene | 0.0268569 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0266897 |
| CREBRF | CREB3 regulatory factor | 0.026484 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0262161 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0259931 |
| HJURP | Holliday junction recognition protein | 0.0259422 |
| YY1AP1 | YY1 associated protein 1 | 0.0258479 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0258126 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0256101 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0255832 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0255658 |
| WDR36 | WD repeat domain 36 | 0.0251251 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0251086 |
| TMEM123 | transmembrane protein 123 | 0.0250896 |
| CALR | calreticulin | 0.024656 |
| UIMC1 | ubiquitin interaction motif containing 1 | 0.0246247 |
| LASP1 | LIM and SH3 protein 1 | 0.0245409 |
| KIAA1328 | KIAA1328 | 0.0245142 |
| FANCI | Fanconi anemia, complementation group I | 0.0244747 |
| ANXA1 | annexin A1 | 0.0244303 |
| DIAPH3 | diaphanous-related formin 3 | 0.0243387 |
| ZNF292 | zinc finger protein 292 | 0.0242248 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0238508 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0236879 |
| CEP295 | centrosomal protein 295kDa | 0.023529 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0234898 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.189049 |
| FNDC3B | fibronectin type III domain containing 3B | -0.151344 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.121435 |
| TMSB10 | thymosin beta 10 | -0.104561 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0946163 |
| PRKCA | protein kinase C, alpha | -0.085267 |
| HMGA2 | high mobility group AT-hook 2 | -0.085237 |
| CD44 | CD44 molecule (Indian blood group) | -0.084406 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.078933 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.075725 |
| POTEF | POTE ankyrin domain family, member F | -0.0687545 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0668384 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.066709 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0568766 |
| NALCN | sodium leak channel, non selective | -0.0541836 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0523919 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0510616 |
| RIGI | RNA sensor RIG-I | -0.0508209 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0506587 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0503985 |
| ATM | ATM serine/threonine kinase | -0.0493145 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0483672 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0475008 |
| ANGPTL4 | angiopoietin-like 4 | -0.0467733 |
| SVIL | supervillin | -0.0457613 |
| DST | dystonin | -0.0455999 |
| PCED1B | PC-esterase domain containing 1B | -0.0451571 |
| PRSS23 | protease, serine, 23 | -0.0433875 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0430907 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0422604 |
| PRR16 | proline rich 16 | -0.0419367 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0414991 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.041356 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0409433 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0402255 |
| ZFHX3 | zinc finger homeobox 3 | -0.0397397 |
| FNDC3A | fibronectin type III domain containing 3A | -0.039621 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0385837 |
| ACTG1 | actin gamma 1 | -0.0380456 |
| FMN1 | formin 1 | -0.0379438 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0379157 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0373315 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0370361 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0369806 |
| RAI14 | retinoic acid induced 14 | -0.036332 |
| S100A6 | S100 calcium binding protein A6 | -0.03631 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0361867 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.035905 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.035687 |
| PODXL | podocalyxin-like | -0.0356245 |
| VCL | vinculin | -0.035312 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0351166 |
| S100A10 | S100 calcium binding protein A10 | -0.0346282 |
| PLEK2 | pleckstrin 2 | -0.0345765 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0342515 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0341521 |
| LDHA | lactate dehydrogenase A | -0.0339575 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0337559 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0334143 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0332983 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0331184 |
| NPAS2 | neuronal PAS domain protein 2 | -0.033064 |
| PKM | pyruvate kinase, muscle | -0.0323447 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0323165 |
| B2M | beta-2-microglobulin | -0.0322233 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0319083 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0315204 |
| EFNA5 | ephrin-A5 | -0.0312859 |
| RPS13 | ribosomal protein S13 | -0.0312369 |
| USP34 | ubiquitin specific peptidase 34 | -0.030991 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0309577 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0305348 |
| BPTF | bromodomain PHD finger transcription factor | -0.0301537 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0300776 |
| ACER3 | alkaline ceramidase 3 | -0.0300555 |
| CDCP1 | CUB domain containing protein 1 | -0.0298634 |
| WWOX | WW domain containing oxidoreductase | -0.0296128 |
| DTNA | dystrobrevin, alpha | -0.0294203 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0289754 |
| RAD51B | RAD51 paralog B | -0.0289403 |
| TBCA | tubulin folding cofactor A | -0.0286688 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0286087 |
| EGR1 | early growth response 1 | -0.0280669 |
| COL5A1 | collagen, type V, alpha 1 | -0.027977 |
| SDC4 | syndecan 4 | -0.0279679 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0279386 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0278662 |
| PARD3 | par-3 family cell polarity regulator | -0.0276848 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0274578 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0272552 |
| NAV3 | neuron navigator 3 | -0.0270596 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0268059 |
| CCNI | cyclin I | -0.0267574 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0267541 |
| PTK2 | protein tyrosine kinase 2 | -0.0267485 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0266736 |
| MAP1B | microtubule-associated protein 1B | -0.0266438 |
| S100A9 | S100 calcium binding protein A9 | -0.0266381 |
| AHNAK | AHNAK nucleoprotein | -0.0266292 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0265028 |