| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Carbidopa (monohydrate)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.123742 |
| NDRG1 | N-myc downstream regulated 1 | 0.110074 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0910992 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0864486 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0788287 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0754912 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0670464 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0640952 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0631879 |
| CA12 | carbonic anhydrase XII | 0.062978 |
| SPAG9 | sperm associated antigen 9 | 0.0573212 |
| GPC6 | glypican 6 | 0.0547947 |
| FA2H | fatty acid 2-hydroxylase | 0.0536222 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0532235 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0490267 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0476074 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0473 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0470205 |
| HIP1 | huntingtin interacting protein 1 | 0.0469765 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0468747 |
| NGLY1 | N-glycanase 1 | 0.0461454 |
| SMAD3 | SMAD family member 3 | 0.0435773 |
| FAM13A | family with sequence similarity 13, member A | 0.0434682 |
| STC1 | stanniocalcin 1 | 0.0434063 |
| KCTD9 | potassium channel tetramerization domain containing 9 | 0.042336 |
| FLNB | filamin B, beta | 0.0420638 |
| PRELID2 | PRELI domain containing 2 | 0.0419566 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0413623 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0404195 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0397145 |
| DUSP5 | dual specificity phosphatase 5 | 0.0384314 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.03777 |
| SEC24A | SEC24 family member A | 0.0376393 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0369793 |
| YEATS2 | YEATS domain containing 2 | 0.0367015 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.036077 |
| OGA | O-GlcNAcase | 0.0354826 |
| FMNL2 | formin-like 2 | 0.0350909 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.033899 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0323842 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0322733 |
| TAOK1 | TAO kinase 1 | 0.0308144 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0307969 |
| RNF145 | ring finger protein 145 | 0.0306514 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0305224 |
| HELZ | helicase with zinc finger | 0.0303058 |
| AXL | AXL receptor tyrosine kinase | 0.030274 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0298503 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0295976 |
| PDE8A | phosphodiesterase 8A | 0.0293644 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.029176 |
| ZFP36 | ZFP36 ring finger protein | 0.0289974 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0285616 |
| SP3 | Sp3 transcription factor | 0.0278065 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0277264 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0276863 |
| SETD5 | SET domain containing 5 | 0.0275807 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0273542 |
| PFKP | phosphofructokinase, platelet | 0.0273334 |
| ZNF292 | zinc finger protein 292 | 0.0272753 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0268837 |
| RNF24 | ring finger protein 24 | 0.0266646 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.026514 |
| PKM | pyruvate kinase, muscle | 0.0265002 |
| ZNF638 | zinc finger protein 638 | 0.0263126 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0262854 |
| CD99 | CD99 molecule | 0.0260631 |
| SRP54 | signal recognition particle 54kDa | 0.0260302 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0258233 |
| USP3 | ubiquitin specific peptidase 3 | 0.0257201 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0255639 |
| CDCP1 | CUB domain containing protein 1 | 0.0246332 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0244783 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0243918 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like | 0.0242498 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0238654 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0234908 |
| PYGL | phosphorylase, glycogen, liver | 0.0233104 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0232017 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0229934 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0229787 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.022917 |
| PHF21A | PHD finger protein 21A | 0.022867 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.022526 |
| WASF2 | WAS protein family, member 2 | 0.0224272 |
| TMEM165 | transmembrane protein 165 | 0.0224247 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0219757 |
| ZBTB25 | zinc finger and BTB domain containing 25 | 0.0219564 |
| CFDP1 | craniofacial development protein 1 | 0.0219256 |
| MTSS1 | metastasis suppressor 1 | 0.02183 |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit | 0.0217062 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0216812 |
| NEMF | nuclear export mediator factor | 0.0215362 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0214747 |
| CDCA2 | cell division cycle associated 2 | 0.0214511 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0210825 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.020996 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0208382 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0208251 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0207043 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.188855 |
| FTL | ferritin, light polypeptide | -0.175817 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.168474 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.119711 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.117612 |
| ANXA2 | annexin A2 | -0.107735 |
| EXT1 | exostosin glycosyltransferase 1 | -0.102505 |
| KYNU | kynureninase | -0.0998744 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0990584 |
| POTEF | POTE ankyrin domain family, member F | -0.0959309 |
| VCL | vinculin | -0.0889566 |
| RPS19 | ribosomal protein S19 | -0.0826396 |
| LDHA | lactate dehydrogenase A | -0.0787929 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0710861 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0691261 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0662638 |
| RPLP1 | ribosomal protein, large, P1 | -0.063301 |
| EGFR | epidermal growth factor receptor | -0.0607706 |
| RPL23 | ribosomal protein L23 | -0.0602 |
| RPL12 | ribosomal protein L12 | -0.0593661 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.059154 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0588623 |
| KRT81 | keratin 81, type II | -0.0583743 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0574651 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0574171 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0573541 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0572841 |
| PDE10A | phosphodiesterase 10A | -0.055673 |
| RPLP0 | ribosomal protein, large, P0 | -0.0553973 |
| MAP1B | microtubule-associated protein 1B | -0.0553741 |
| ANXA1 | annexin A1 | -0.0547569 |
| VIM | vimentin | -0.054525 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0543392 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0531186 |
| RHCG | Rh family, C glycoprotein | -0.0524096 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0521106 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0510914 |
| MT2A | metallothionein 2A | -0.0491588 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | -0.0472834 |
| VMP1 | vacuole membrane protein 1 | -0.0468838 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.046183 |
| TPM1 | tropomyosin 1 (alpha) | -0.0459796 |
| RPS16 | ribosomal protein S16 | -0.0452637 |
| NTN4 | netrin 4 | -0.0452425 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0448858 |
| RPL13A | ribosomal protein L13a | -0.0447362 |
| GLIS3 | GLIS family zinc finger 3 | -0.0437507 |
| ENO1 | enolase 1, (alpha) | -0.043469 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0434007 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0432597 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0431435 |
| KRT7 | keratin 7, type II | -0.0428179 |
| EZR | ezrin | -0.0425184 |
| OSMR | oncostatin M receptor | -0.0424744 |
| TNS3 | tensin 3 | -0.0412846 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0408626 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0405278 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.040172 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0400911 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0399967 |
| LMO7 | LIM domain 7 | -0.0395778 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0393786 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0389986 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0385377 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0384287 |
| BICC1 | BicC family RNA binding protein 1 | -0.0384253 |
| RAI14 | retinoic acid induced 14 | -0.0381747 |
| KRT18 | keratin 18, type I | -0.0381134 |
| FBXO11 | F-box protein 11 | -0.0380517 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0380495 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0377936 |
| TKT | transketolase | -0.037594 |
| RACK1 | receptor for activated C kinase 1 | -0.037505 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0372738 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0367314 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0366871 |
| CCDC88A | coiled-coil domain containing 88A | -0.0361697 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0359952 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.035925 |
| EHBP1 | EH domain binding protein 1 | -0.0356337 |
| RPL19 | ribosomal protein L19 | -0.035427 |
| RPS5 | ribosomal protein S5 | -0.0349505 |
| S100A6 | S100 calcium binding protein A6 | -0.0347411 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0346265 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0345619 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0335765 |
| RPL11 | ribosomal protein L11 | -0.0329808 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.032972 |
| PTK2 | protein tyrosine kinase 2 | -0.0329307 |
| SP100 | SP100 nuclear antigen | -0.0329026 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0328007 |
| PCBP2 | poly(rC) binding protein 2 | -0.031772 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0315347 |
| WWC1 | WW and C2 domain containing 1 | -0.0311412 |
| PFN1 | profilin 1 | -0.0307771 |
| RSPO3 | R-spondin 3 | -0.0305495 |
| ACTN4 | actinin, alpha 4 | -0.030506 |
| IGF1R | insulin-like growth factor 1 receptor | -0.030401 |
| RPS6 | ribosomal protein S6 | -0.0303683 |
| RPL31 | ribosomal protein L31 | -0.0303481 |
