| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Carbidopa (monohydrate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.167716 |
| ZNF292 | zinc finger protein 292 | 0.110931 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0557726 |
| PRELID2 | PRELI domain containing 2 | 0.0534181 |
| RNF145 | ring finger protein 145 | 0.051953 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0486931 |
| QKI | QKI, KH domain containing, RNA binding | 0.04803 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0476547 |
| VEGFA | vascular endothelial growth factor A | 0.046644 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0427221 |
| MED13L | mediator complex subunit 13-like | 0.0403319 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0391083 |
| CDK19 | cyclin-dependent kinase 19 | 0.0390173 |
| HOXA3 | homeobox A3 | 0.038919 |
| PHIP | pleckstrin homology domain interacting protein | 0.0386613 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.03773 |
| DIPK2A | divergent protein kinase domain 2A | 0.0375251 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0368904 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | 0.0360188 |
| RFX7 | regulatory factor X, 7 | 0.0352756 |
| XPO1 | exportin 1 | 0.0352226 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0348009 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0323195 |
| USP3 | ubiquitin specific peptidase 3 | 0.0314406 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0297904 |
| OGA | O-GlcNAcase | 0.0291656 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0287289 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0286934 |
| ETNK1 | ethanolamine kinase 1 | 0.0286656 |
| BCOR | BCL6 corepressor | 0.02859 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0285281 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0279221 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.027546 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0274137 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0264264 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0260412 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0259668 |
| CCNL1 | cyclin L1 | 0.0257934 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0257313 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0256963 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0256893 |
| ZNF148 | zinc finger protein 148 | 0.0254208 |
| SMAP1 | small ArfGAP 1 | 0.0252985 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0249766 |
| SGCE | sarcoglycan, epsilon | 0.0245989 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0240268 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0239357 |
| RAB6A | RAB6A, member RAS oncogene family | 0.023922 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.0238457 |
| LMO4 | LIM domain only 4 | 0.0237266 |
| INSIG2 | insulin induced gene 2 | 0.0236849 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0236253 |
| TPM3 | tropomyosin 3 | 0.0236253 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0234679 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0234342 |
| FAM133B | family with sequence similarity 133, member B | 0.0234158 |
| RLF | rearranged L-myc fusion | 0.0233892 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0233624 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0232572 |
| ZNF654 | zinc finger protein 654 | 0.0231904 |
| TFG | TRK-fused gene | 0.0229667 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0227308 |
| FNIP1 | folliculin interacting protein 1 | 0.0227292 |
| MEF2A | myocyte enhancer factor 2A | 0.0226962 |
| KIF1B | kinesin family member 1B | 0.0224512 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0223652 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0222691 |
| NEK7 | NIMA-related kinase 7 | 0.0222234 |
| ECT2 | epithelial cell transforming 2 | 0.0221052 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.022045 |
| FN1 | fibronectin 1 | 0.021912 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.021912 |
| RO60 | Ro60, Y RNA binding protein | 0.0217874 |
| PDGFC | platelet derived growth factor C | 0.0216886 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0216849 |
| KIF18B | kinesin family member 18B | 0.0213809 |
| WDR11 | WD repeat domain 11 | 0.0212614 |
| SBF2 | SET binding factor 2 | 0.0211614 |
| SLTM | SAFB-like, transcription modulator | 0.0210957 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 0.0210885 |
| CCPG1 | cell cycle progression 1 | 0.0210324 |
| RBM33 | RNA binding motif protein 33 | 0.0209948 |
| YEATS2 | YEATS domain containing 2 | 0.020857 |
| ITM2B | integral membrane protein 2B | 0.0207749 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0207436 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0206747 |
| RNF150 | ring finger protein 150 | 0.020662 |
| KMT5B | lysine methyltransferase 5B | 0.0206319 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0205464 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0204116 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0203649 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0202296 |
| PDS5A | PDS5 cohesin associated factor A | 0.0201543 |
| RYBP | RING1 and YY1 binding protein | 0.0200188 |
| SNX13 | sorting nexin 13 | 0.0199909 |
| TMF1 | TATA element modulatory factor 1 | 0.0199908 |
| KLF10 | Kruppel-like factor 10 | 0.0199472 |
| PDE8A | phosphodiesterase 8A | 0.0199228 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.01989 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | 0.0198118 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | -0.163455 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.142925 |
| PTMA | prothymosin, alpha | -0.117672 |
| PEG10 | paternally expressed 10 | -0.113694 |
| VIM | vimentin | -0.112396 |
| HMGA2 | high mobility group AT-hook 2 | -0.101946 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0841702 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0810282 |
| RANBP17 | RAN binding protein 17 | -0.0806819 |
| CANX | calnexin | -0.0771305 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0745323 |
| KAZN | kazrin, periplakin interacting protein | -0.0722274 |
| RPS24 | ribosomal protein S24 | -0.0716476 |
| TMSB10 | thymosin beta 10 | -0.0690315 |
| ACTG1 | actin gamma 1 | -0.0681826 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0680113 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0674223 |
| RPL35A | ribosomal protein L35a | -0.0657248 |
| MGP | matrix Gla protein | -0.0655197 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0650098 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0636066 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0635613 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0611598 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.060492 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.060083 |
| RPS23 | ribosomal protein S23 | -0.0575067 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0571622 |
| RPS27A | ribosomal protein S27a | -0.0569171 |
| CDK6 | cyclin-dependent kinase 6 | -0.056312 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0557268 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0556909 |
| RPL37A | ribosomal protein L37a | -0.0552296 |
| FTL | ferritin, light polypeptide | -0.0543395 |
| TUBB | tubulin, beta class I | -0.0532894 |
| RPS8 | ribosomal protein S8 | -0.0532308 |
| ENO1 | enolase 1, (alpha) | -0.0531976 |
| RPL11 | ribosomal protein L11 | -0.0504807 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0496458 |
| VCL | vinculin | -0.0489613 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0472968 |
| RPL12 | ribosomal protein L12 | -0.0472721 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0472595 |
| CUX1 | cut-like homeobox 1 | -0.0467226 |
| RPL37 | ribosomal protein L37 | -0.0460572 |
| TMSB4X | thymosin beta 4, X-linked | -0.0459844 |
| RPL23 | ribosomal protein L23 | -0.0457599 |
| RPL19 | ribosomal protein L19 | -0.0457371 |
| MAP1B | microtubule-associated protein 1B | -0.0448686 |
| RPL31 | ribosomal protein L31 | -0.0444011 |
| RPS3 | ribosomal protein S3 | -0.0441292 |
| CTBP2 | C-terminal binding protein 2 | -0.0440082 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.043796 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0433463 |
| RPLP2 | ribosomal protein, large, P2 | -0.0423318 |
| RPLP0 | ribosomal protein, large, P0 | -0.0419679 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0419337 |
| RPL34 | ribosomal protein L34 | -0.0406531 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0398778 |
| MT2A | metallothionein 2A | -0.0396419 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0394227 |
| RPL36 | ribosomal protein L36 | -0.038018 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0377851 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0368055 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0362168 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0359716 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0354757 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.035076 |
| SEPTIN11 | septin 11 | -0.0348281 |
| EXOC4 | exocyst complex component 4 | -0.0346627 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.03454 |
| HLA-B | major histocompatibility complex, class I, B | -0.0340226 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0333003 |
| RPL26 | ribosomal protein L26 | -0.0331378 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | -0.0330888 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0329871 |
| APP | amyloid beta (A4) precursor protein | -0.0327958 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0326605 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0326369 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) | -0.0325962 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0320543 |
| PARD3 | par-3 family cell polarity regulator | -0.0320409 |
| RPS16 | ribosomal protein S16 | -0.0319387 |
| TULP4 | tubby like protein 4 | -0.0318806 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.03171 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0314408 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0312998 |
| ATXN2 | ataxin 2 | -0.0310578 |
| PBRM1 | polybromo 1 | -0.0309946 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0307524 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0304237 |
| RPS13 | ribosomal protein S13 | -0.0301745 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0298913 |
| SMYD3 | SET and MYND domain containing 3 | -0.0296915 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0296636 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0295425 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0293856 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | -0.0293723 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0284057 |
| RPLP1 | ribosomal protein, large, P1 | -0.0283046 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0279673 |
