| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Carbidopa (monohydrate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.126845 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.118707 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0926164 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0797425 |
| PTMA | prothymosin, alpha | 0.0721762 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0682276 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0608606 |
| VIM | vimentin | 0.0597199 |
| NDRG1 | N-myc downstream regulated 1 | 0.058953 |
| HMGA1 | high mobility group AT-hook 1 | 0.0566459 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0532855 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0531217 |
| FAM13A | family with sequence similarity 13, member A | 0.052972 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0510866 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0482198 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0481334 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0480263 |
| FAM3C | family with sequence similarity 3, member C | 0.0453549 |
| S100A4 | S100 calcium binding protein A4 | 0.0442063 |
| ITGA6 | integrin, alpha 6 | 0.0404721 |
| S100A10 | S100 calcium binding protein A10 | 0.0401528 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0396056 |
| PERP | PERP, TP53 apoptosis effector | 0.037567 |
| RPS6 | ribosomal protein S6 | 0.0372594 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0366686 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0366457 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0365289 |
| MUC17 | mucin 17, cell surface associated | 0.036034 |
| RPL35A | ribosomal protein L35a | 0.0355193 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0353483 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0351166 |
| VCAN | versican | 0.0349745 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0347091 |
| FAM107B | family with sequence similarity 107, member B | 0.0343595 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0330631 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.033033 |
| RPLP0 | ribosomal protein, large, P0 | 0.0317427 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0311456 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0311363 |
| PGK1 | phosphoglycerate kinase 1 | 0.030795 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.030013 |
| S100A6 | S100 calcium binding protein A6 | 0.0298571 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 0.0296483 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0291678 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0287862 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0284806 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0283752 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0275863 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0275522 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0274928 |
| FOSL1 | FOS-like antigen 1 | 0.0273709 |
| JMJD1C | jumonji domain containing 1C | 0.0273577 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0273206 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0268272 |
| RPL12 | ribosomal protein L12 | 0.0265129 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0264695 |
| SLK | STE20-like kinase | 0.0263933 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0257474 |
| S100A11 | S100 calcium binding protein A11 | 0.0257255 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0252376 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0250537 |
| CSTB | cystatin B (stefin B) | 0.0250074 |
| USP3 | ubiquitin specific peptidase 3 | 0.0248445 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0246635 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 0.02432 |
| INSIG2 | insulin induced gene 2 | 0.0241102 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.0238589 |
| XPO1 | exportin 1 | 0.0236975 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0236122 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0235602 |
| KLK10 | kallikrein-related peptidase 10 | 0.0234145 |
| CDCP1 | CUB domain containing protein 1 | 0.0233893 |
| ITGAV | integrin, alpha V | 0.0229571 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0228994 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0228663 |
| ARRDC3 | arrestin domain containing 3 | 0.0227222 |
| OGA | O-GlcNAcase | 0.0226027 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0223454 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0222737 |
| TMEM123 | transmembrane protein 123 | 0.0220605 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0217414 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.021662 |
| OPTN | optineurin | 0.0213616 |
| RPS20 | ribosomal protein S20 | 0.0212199 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0211313 |
| WASF2 | WAS protein family, member 2 | 0.0211032 |
| RNF145 | ring finger protein 145 | 0.0210622 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.020974 |
| FERMT1 | fermitin family member 1 | 0.0208581 |
| TMEM41B | transmembrane protein 41B | 0.0205441 |
| ANLN | anillin, actin binding protein | 0.0201996 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.020184 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0201578 |
| SLTM | SAFB-like, transcription modulator | 0.0199407 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0197975 |
| PLAG1 | pleiomorphic adenoma gene 1 | 0.0196849 |
| SERTAD2 | SERTA domain containing 2 | 0.0196632 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 0.0194493 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0192616 |
| CD9 | CD9 molecule | 0.0192449 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.23235 |
| LAMB3 | laminin, beta 3 | -0.166858 |
| FLNB | filamin B, beta | -0.146193 |
| AHNAK | AHNAK nucleoprotein | -0.125727 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.118492 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.096807 |
| PARD3 | par-3 family cell polarity regulator | -0.086228 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0857718 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0846466 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0768747 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0725972 |
| MCL1 | myeloid cell leukemia 1 | -0.0709715 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0694608 |
| PLEC | plectin | -0.0689097 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0688176 |
| RASAL2 | RAS protein activator like 2 | -0.0685101 |
| PMM2 | phosphomannomutase 2 | -0.0652891 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0630568 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.060549 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0591775 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0586665 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0582486 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.057499 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0549014 |
| TRRAP | transformation/transcription domain-associated protein | -0.0548912 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0543511 |
| VMP1 | vacuole membrane protein 1 | -0.0510775 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0510077 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | -0.0509691 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0507201 |
| ACTN4 | actinin, alpha 4 | -0.0505279 |
| CORO1C | coronin, actin binding protein, 1C | -0.0504843 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0504282 |
| ASPH | aspartate beta-hydroxylase | -0.0495817 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0478462 |
| EFNA5 | ephrin-A5 | -0.047444 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0473823 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0471605 |
| SMAD3 | SMAD family member 3 | -0.0467218 |
| EZR | ezrin | -0.0460244 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0456939 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0454785 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0443025 |
| TPM3 | tropomyosin 3 | -0.0442533 |
| HDAC9 | histone deacetylase 9 | -0.0441315 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0435441 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0430082 |
| USP34 | ubiquitin specific peptidase 34 | -0.0420022 |
| HDLBP | high density lipoprotein binding protein | -0.0411081 |
| RPS27A | ribosomal protein S27a | -0.0403218 |
| TXNRD1 | thioredoxin reductase 1 | -0.0403055 |
| CALU | calumenin | -0.0401639 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0399241 |
| TJP1 | tight junction protein 1 | -0.039918 |
| FMNL2 | formin-like 2 | -0.0399092 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0389554 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.038321 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | -0.0382398 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0379298 |
| PTK2 | protein tyrosine kinase 2 | -0.0369598 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0368209 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0367377 |
| NABP1 | nucleic acid binding protein 1 | -0.0367018 |
| LAMC2 | laminin, gamma 2 | -0.0363169 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | -0.0360845 |
| APP | amyloid beta (A4) precursor protein | -0.0355565 |
| RAB7A | RAB7A, member RAS oncogene family | -0.035163 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.034976 |
| INTS6 | integrator complex subunit 6 | -0.0345575 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0345092 |
| RBM39 | RNA binding motif protein 39 | -0.0343 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0342114 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0342104 |
| EGFR | epidermal growth factor receptor | -0.0332987 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0332348 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.033144 |
| OXSR1 | oxidative stress responsive 1 | -0.0331292 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0329968 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0328479 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0326507 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0325502 |
| CDK13 | cyclin-dependent kinase 13 | -0.0324201 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0316954 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0313198 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0311972 |
| SEPTIN10 | septin 10 | -0.0311853 |
| SGMS2 | sphingomyelin synthase 2 | -0.030968 |
| KRT8 | keratin 8, type II | -0.0306229 |
| SEPTIN9 | septin 9 | -0.0306056 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.030464 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0302402 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0302133 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0300192 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0297674 |
| TGM2 | transglutaminase 2 | -0.029752 |
| BCL2L1 | BCL2-like 1 | -0.0295961 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0295508 |
| MYO5B | myosin VB | -0.0294722 |
| FUS | FUS RNA binding protein | -0.0294158 |
| BMP6 | bone morphogenetic protein 6 | -0.0293819 |
