| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Carbidopa (monohydrate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Carbidopa (monohydrate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.211202 |
| GPC6 | glypican 6 | 0.135657 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.111418 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.105915 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.105381 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0929797 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0837647 |
| MT2A | metallothionein 2A | 0.0756726 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0725352 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0676883 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0656221 |
| TNNC1 | troponin C type 1 (slow) | 0.0633569 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0626067 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0624341 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0614575 |
| TMEM178B | transmembrane protein 178B | 0.0599625 |
| AHR | aryl hydrocarbon receptor | 0.0564425 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0563859 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0539463 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0517819 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0516681 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0514435 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0490002 |
| SETBP1 | SET binding protein 1 | 0.0475782 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0468683 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0468284 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0442886 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0431708 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0419464 |
| SRPK2 | SRSF protein kinase 2 | 0.0418002 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0415921 |
| PCDH7 | protocadherin 7 | 0.0415155 |
| OXR1 | oxidation resistance 1 | 0.03973 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.039405 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.039159 |
| EXOC4 | exocyst complex component 4 | 0.0387702 |
| OSMR | oncostatin M receptor | 0.0387239 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0375912 |
| NHSL1 | NHS-like 1 | 0.0374057 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0353044 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0347382 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.0346721 |
| SAMTOR | S-adenosylmethionine sensor upstream of mTORC1 | 0.0345767 |
| COG5 | component of oligomeric golgi complex 5 | 0.0344412 |
| IL6ST | interleukin 6 signal transducer | 0.0340911 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0340416 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0338903 |
| KLHDC10 | kelch domain containing 10 | 0.0337236 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0337228 |
| FAM3C | family with sequence similarity 3, member C | 0.0336895 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0333645 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0323537 |
| MED13L | mediator complex subunit 13-like | 0.0322242 |
| PI15 | peptidase inhibitor 15 | 0.0317601 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0314407 |
| MTPN | myotrophin | 0.0314398 |
| CDC73 | cell division cycle 73 | 0.0310468 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0308088 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0298272 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0297496 |
| PRELID2 | PRELI domain containing 2 | 0.0296494 |
| CDH19 | cadherin 19, type 2 | 0.0275422 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0275038 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0274869 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0269166 |
| RO60 | Ro60, Y RNA binding protein | 0.0269097 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0268082 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0262916 |
| ACER3 | alkaline ceramidase 3 | 0.0260368 |
| MT1X | metallothionein 1X | 0.0256742 |
| VMP1 | vacuole membrane protein 1 | 0.0255033 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0253555 |
| LRAT | lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) | 0.0252524 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0250538 |
| FOSL1 | FOS-like antigen 1 | 0.0249961 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0249498 |
| PRKD1 | protein kinase D1 | 0.0248833 |
| CDK8 | cyclin-dependent kinase 8 | 0.0248106 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0244702 |
| USP53 | ubiquitin specific peptidase 53 | 0.0241362 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0239703 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0239225 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0237099 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0235967 |
| SNX1 | sorting nexin 1 | 0.0233127 |
| RCAN1 | regulator of calcineurin 1 | 0.0231962 |
| ARRDC3 | arrestin domain containing 3 | 0.0229842 |
| DOCK7 | dedicator of cytokinesis 7 | 0.0229172 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0227382 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0226833 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 0.0224939 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.02247 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0221647 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | 0.0218 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0217758 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0215501 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0212656 |
| ANKRD28 | ankyrin repeat domain 28 | 0.021179 |
| DICER1 | dicer 1, ribonuclease type III | 0.0210973 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0210231 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.209699 |
| VGF | VGF nerve growth factor inducible | -0.172057 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.135119 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.109128 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.100025 |
| CALU | calumenin | -0.0892653 |
| NDRG1 | N-myc downstream regulated 1 | -0.0814676 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0682469 |
| ENO1 | enolase 1, (alpha) | -0.0649388 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0647593 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0640795 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0632024 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0597256 |
| NPR2 | natriuretic peptide receptor 2 | -0.056415 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0549056 |
| TRIM2 | tripartite motif containing 2 | -0.0547704 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0530443 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0520402 |
| PTK2 | protein tyrosine kinase 2 | -0.0517719 |
| CANX | calnexin | -0.0499008 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0484948 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0480717 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0448609 |
| ADM | adrenomedullin | -0.044412 |
| POTEF | POTE ankyrin domain family, member F | -0.0439919 |
| PTMA | prothymosin, alpha | -0.043603 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0426575 |
| FTL | ferritin, light polypeptide | -0.0425841 |
| CENPF | centromere protein F, 350/400kDa | -0.0417825 |
| JUN | jun proto-oncogene | -0.0410138 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0407036 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.040146 |
| NLGN1 | neuroligin 1 | -0.0394951 |
| HLA-B | major histocompatibility complex, class I, B | -0.0392457 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0387889 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0387675 |
| MYO1E | myosin IE | -0.0386261 |
| EGR1 | early growth response 1 | -0.0379221 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0378182 |
| ACTG1 | actin gamma 1 | -0.0374311 |
| S100A6 | S100 calcium binding protein A6 | -0.0372979 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0370372 |
| CTTNBP2 | cortactin binding protein 2 | -0.0365547 |
| IRS2 | insulin receptor substrate 2 | -0.0361509 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0359794 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0357243 |
| MYOF | myoferlin | -0.0356355 |
| CALR | calreticulin | -0.0351524 |
| LRRC23 | leucine rich repeat containing 23 | -0.0346992 |
| ZNF704 | zinc finger protein 704 | -0.0332451 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0331167 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0326351 |
| GDF15 | growth differentiation factor 15 | -0.032489 |
| CADM1 | cell adhesion molecule 1 | -0.0317719 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0317707 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0317028 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0315999 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0313948 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0306927 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.030667 |
| CUX1 | cut-like homeobox 1 | -0.0303663 |
| DST | dystonin | -0.0303324 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.03032 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0296855 |
| HSPB1 | heat shock 27kDa protein 1 | -0.029621 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.0292037 |
| FUS | FUS RNA binding protein | -0.0290201 |
| LMNA | lamin A/C | -0.0289941 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0289163 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0288403 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0286358 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0276837 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0272457 |
| MYO10 | myosin X | -0.0271562 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0270922 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0269935 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0269889 |
| RYBP | RING1 and YY1 binding protein | -0.0268326 |
| CALD1 | caldesmon 1 | -0.0261493 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0259785 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0257999 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.025797 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0257179 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0256173 |
| CD44 | CD44 molecule (Indian blood group) | -0.0255034 |
| SMAD3 | SMAD family member 3 | -0.0254364 |
| NAV3 | neuron navigator 3 | -0.0254134 |
| MORF4L2 | mortality factor 4 like 2 | -0.0251931 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.025103 |
| B2M | beta-2-microglobulin | -0.0248277 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.024749 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0242209 |
| HLA-A | major histocompatibility complex, class I, A | -0.023788 |
| TFRC | transferrin receptor | -0.023687 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0236487 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0235772 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0234306 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | -0.0233592 |
| AHNAK | AHNAK nucleoprotein | -0.0231009 |
| TMSB10 | thymosin beta 10 | -0.023067 |
